Results 71 to 80 of about 2,747,705 (306)

Reformulating lipid nanoparticles for organ-targeted mRNA accumulation and translation

open access: yesNature Communications
Fully targeted mRNA therapeutics necessitate simultaneous organ-specific accumulation and effective translation. Despite some progress, delivery systems are still unable to fully achieve this.
Kexin Su   +16 more
doaj   +1 more source

The synergistic antitumor activity of 3-(2-nitrophenyl) propionic acid-paclitaxel nanoparticles (NPPA-PTX NPs) and anti-PD-L1 antibody inducing immunogenic cell death

open access: yesDrug Delivery, 2021
Cancer immunotherapy is a strategy that is moving to the frontier of cancer treatment in the current decade. In this study, we show evidence that 3-(2-nitrophenyl) propionic acid-paclitaxel nanoparticles (NPPA-PTX NPs), act as immunogenic cell death (ICD)
Xiao-Chuan Duan   +12 more
doaj   +1 more source

Generalized decoding, effective channels, and simplified security proofs in quantum key distribution

open access: yes, 2005
Prepare and measure quantum key distribution protocols can be decomposed into two basic steps: delivery of the signals over a quantum channel and distillation of a secret key from the signal and measurement records by classical processing and public ...
Grassl, Markus, Renes, Joseph M.
core   +1 more source

Revealing the structure of land plant photosystem II: the journey from negative‐stain EM to cryo‐EM

open access: yesFEBS Letters, EarlyView.
Advances in cryo‐EM have revealed the detailed structure of Photosystem II, a key protein complex driving photosynthesis. This review traces the journey from early low‐resolution images to high‐resolution models, highlighting how these discoveries deepen our understanding of light harvesting and energy conversion in plants.
Roman Kouřil
wiley   +1 more source

One Stone Four Birds: A Novel Liposomal Delivery System Multi-functionalized with Ginsenoside Rh2 for Tumor Targeting Therapy

open access: yesNano-Micro Letters, 2020
Liposomes hold great potential in anti-cancer drug delivery and the targeting treatment of tumors. However, the clinical therapeutic efficacy of liposomes is still limited by the complexity of tumor microenvironment (TME) and the insufficient ...
Chao Hong   +12 more
doaj   +1 more source

Reducing Inequalities in Water Supply, Sanitation, and Hygiene in the Era of the Sustainable Development Goals [PDF]

open access: yes, 2017
The Sustainable Development Goals (SDGs) and the World Bank's corporate goals of ending extreme poverty and boosting shared prosperity call for specific attention to the poor and vulnerable.
Craig Kullman   +3 more
core   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Key New Hampshire and Federal Statutes Regulating Health Care Delivery and Payment [PDF]

open access: yes, 2017
A summary of New Hampshire and federal regulations by subject matter, chart of New Hampshire state agency responsibilities, federal laws and regulation: An ...
Hodder, Lucy C.
core   +4 more sources

Panax notoginseng: derived exosome-like nanoparticles attenuate ischemia reperfusion injury via altering microglia polarization

open access: yesJournal of Nanobiotechnology, 2023
Cerebral ischemia/reperfusion (CI/R) injury is a clinical conundrum during the treatment of ischemic stroke. Cell-derived exosomes (CDE) were proved to be therapeutically effective for CI/R injury. However, production of CDE is time and effort consuming.
Shiyi Li   +10 more
doaj   +1 more source

Key skills by design: Adapting a central Web resource to departmental contexts [PDF]

open access: yes, 2002
Web‐based delivery of support materials for students has proved to be a popular way of helping small teams to implement key skills policies within universities. The development of ‘key’ or ‘transferable’ skills is now encouraged throughout education, but
McAvinia, Claire
core   +3 more sources

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