Results 61 to 70 of about 911,306 (169)

Modulating nuclear stiffness and envelope barrier facilitates AAV nuclear entry and reduces immunogenicity

Nature Communications
Recombinant adeno-associated viruses (rAAVs) have shown promise for orthopedic diseases. However, conventional AAV vectors face major challenges, where immune responses reduce transgene efficacy and inadequate vector potency requires higher doses ...
Yangsen Ou, Fuhua Wu, Chunting He, Shuang Luo, Zhaofei Guo, Yongshun Zhang, Rui Hu, Yanhua Xu, Xue Tang, Yuanhao Zhao, Lin Ye, Xiaoyan Chen, Shuting Bai, Guangsheng Du, Xun Sun   +14 more
doaj   +1 more source

Naringenin: A potential therapeutic agent for modulating angiogenesis and immune response in hepatocellular carcinoma

Journal of Pharmaceutical Analysis
Naringenin (4,5,7-trihydroxyflavonoid) is a naturally occurring bioflavonoid found in citrus fruits, which plays an important role in metabolic syndrome, neurological disorders, and cardiovascular diseases.
Wenmei Wu, Xiangyu Qiu, Xiaofan Ye, Zhiliang Zhang, Siguo Xu, Xiuqi Yao, Yinyi Du, Geyan Wu, Rongxin Zhang, Jinrong Zhu   +9 more
doaj   +1 more source

Modulating active targeting nanoparticle design according to tumor progressions

Acta Pharmaceutica Sinica B
Targeting drug delivery systems mediated by nanoparticles has shown great potential in the diagnosis and treatment of cancer. However, influences of different tumor progressions on the accumulation of nanoparticles, especially the ligand-modified active ...
Huifang Nie, Rong Huang, Guangwei Jiang, Wenshuai Li, Lan Yang, Meng Zhang, Min Qian, Wei Guo, Tao Ye, Rongqin Huang   +9 more
doaj   +1 more source

Deciphering the mechanisms of long non-coding RNAs in ferroptosis: insights into its clinical significance in cancer progression and immunology

Cell Death Discovery
A new type of nonapoptotic, iron-dependent cell death induced by lipid peroxidation is known as ferroptosis. Numerous pathological processes, including inflammation and cancer, have been demonstrated to be influenced by changes in the ferroptosis ...
Shengming Ou, Xiaoya Nie, Xiangyu Qiu, Xin Jin, Geyan Wu, Rongxin Zhang, Jinrong Zhu   +6 more
doaj   +1 more source

ZETA POTENTIAL: A KEY FACTOR IN DRUG DELIVERY

This review article deals with measurement and applications of zeta potential, zeta potential in pharmaceutical formulation, Role of zeta potential in stability, material design and preparation. Zeta potential (ζ) is a measure of the magnitude of the repulsion or attraction between particles.
Kalpana Devi*, Gokul Kanna V., Gokula Krishnan S., Gokula Kannan P., Dr. K. G. Parthiban   +4 more
openaire   +1 more source

Bacterial mRNA Vaccines: Programming Immunity Against Antimicrobial Resistance. [PDF]

Drug Dev Res
Liao R, Luo M, Yang F, Xu L, Zhang J, Zhang W, Guan S, Zhang Y, Luo P, Cheng P, Yang J, Li Y, Wang Q.   +12 more
europepmc   +1 more source

A Thematic Analysis of Key Informant Interviews on the Implementation Experience of the HEARTS Hypertension Program in Nigeria. [PDF]

Glob Heart
Husain MJ, Toma MM, Eze SV, Osi K, Ogbureke N, Erojikwe O, Kostova D, Moran AE, Banigbe BF, Sambo EN.   +9 more
europepmc   +1 more source

Pulmonary surfactant camouflage lipid nanoparticles for efficient mRNA lung delivery. [PDF]

Signal Transduct Target Ther
Sun W, Zhou TQ, Huang Y, Liang XJ, Li F.
europepmc   +1 more source

Drug Delivery for tuberculosis: is Inhaled Therapy the Key to success? [PDF]

Therapeutic Delivery, 2017
Daniela, Traini, Paul M, Young
openaire   +2 more sources

Highly cited original research in microneedle science from 2015 to 2025 a bibliometric and altmetric analysis. [PDF]

Discov Nano
Chen X, Zhang Q, Zhao C, Wang G, Ren H, Yang M, Liu S, Liu T, Guo B.   +8 more
europepmc   +1 more source