Results 51 to 60 of about 2,783,643 (311)

The design, implementation and evaluation of mass conferencing [PDF]

, 1998
There have been attempts to classify and analyse the approaches and techniques of using videoconferencing for teaching and learning. Most classifications include the use of videoconferencing techniques to support lecture‐style delivery to large audiences,
Brady, Sean, Clarkson, Jean, Donert, Karl   +2 more
core   +3 more sources

Financial Burden Associated With Hospitalisation Among Families of Childhood Brain Tumours in Australia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Families of children with cancer experience significant financial strain, even with universal healthcare. Indirect costs, such as productivity losses and non‐medical expenses, are rarely included in economic evaluations, and little is known about how effectively financial aid programmes alleviate this burden. Childhood brain tumours
Megumi Lim, Natalie Bradford, David Brain, Sameera Senanayake, Sanjeewa Kularatna, Kate Young, Christine Cashion, Tim Hassall, Susanna Cramb   +8 more
wiley   +1 more source

Sequential delivery of PD-1/PD-L1 blockade peptide and IDO inhibitor for immunosuppressive microenvironment remodeling via an MMP-2 responsive dual-targeting liposome

Acta Pharmaceutica Sinica B, 2023
Intelligent responsive drug delivery system opens up new avenues for realizing safer and more effective combination immunotherapy. Herein, a kind of tumor cascade-targeted responsive liposome (NLG919@Lip-pep1) is developed by conjugating polypeptide ...
Chuan Hu, Yujun Song, Yiwei Zhang, Siqin He, Xueying Liu, Xiaotong Yang, Tao Gong, Yuan Huang, Huile Gao   +8 more
doaj   +1 more source

Role of size, surface charge, and PEGylated lipids of lipid nanoparticles (LNPs) on intramuscular delivery of mRNA

Journal of Nanobiotechnology
Lipid nanoparticles (LNPs) are currently the most commonly used non-viral gene delivery system. Their physiochemical attributes, encompassing size, charge and surface modifications, significantly affect their behaviors both in vivo and in vitro ...
Weiwen Kong, Yuning Wei, Zirong Dong, Wenjuan Liu, Jiaxin Zhao, Yan Huang, Jinlong Yang, Wei Wu, Haisheng He, Jianping Qi   +9 more
doaj   +1 more source

Factors affecting home delivery in rural Tanzania [PDF]

, 2007
BACKGROUND\ud \ud Studies of factors affecting place of delivery have rarely considered the influence of gender roles and relations within the household.
Mrisho, M, Mshinda, H, Mushi, A, Obrist, B, Schellenberg, D, Schellenberg, JA, Tanner, M   +6 more
core   +2 more sources

Macrophage based drug delivery: Key challenges and strategies

Bioactive Materials
As a natural immune cell and antigen presenting cell, macrophages have been studied and engineered to treat human diseases. Macrophages are well-suited for use as drug carriers because of their biological characteristics, such as excellent biocompatibility, long circulation, intrinsic inflammatory homing and phagocytosis.
Qian Guo, Zhong-Ming Qian
openaire   +3 more sources

‘They Need to Hear You Say It’: Healthcare Professionals’ Perspectives on Barriers and Enablers to End‐of‐Life Discussions With Adolescents and Young Adults With Cancer

Pediatric Blood &Cancer, EarlyView.
ABSTRACT End‐of‐life conversations with adolescents and young adults (AYAs) with cancer rarely occur without the guidance of healthcare professionals. As a part of the ‘Difficult Discussions’ study, focused on palliative care and advance care planning discussions with AYAs with cancer, we investigated the factors that healthcare professionals identify ...
Justine Lee, Holly Evans, Claire E. Wakefield, Antoinette Anazodo, Richard J. Cohn, Brittany C. McGill, Elizabeth A. Lobb, Lori Wiener, Madeleine L. Juhrmann, Ursula M. Sansom‐Daly   +9 more
wiley   +1 more source

MMP-2-triggered, mitochondria-targeted PROTAC-PDT therapy of breast cancer and brain metastases inhibition

Nature Communications
Proteolytic targeting chimera (PROTAC) technology is a protein-blocking technique and induces antitumor effects, with potential advantages. However, its effect is limited by insufficient distribution and accumulation in tumors.
Fan Tong, Yufan Wang, Yanyan Xu, Yang Zhou, Siqin He, Yufan Du, Wenqin Yang, Ting Lei, Yujun Song, Tao Gong, Huile Gao   +10 more
doaj   +1 more source

Human Vault Nanoparticle Targeted Delivery of Antiretroviral Drugs to Inhibit Human Immunodeficiency Virus Type 1 Infection. [PDF]

, 2019
"Vaults" are ubiquitously expressed endogenous ribonucleoprotein nanoparticles with potential utility for targeted drug delivery. Here, we show that recombinant human vault nanoparticles are readily engulfed by certain key human peripheral blood ...
Anton, Peter A, Deming, Timothy, Elliott, Julie, Fulcher, Jennifer A, Ibarrondo, F Javier, Kickhoefer, Valerie A, Maynard, Heather D, Mrazek, Jan, Rome, Leonard H, Tamshen, Kyle, Wollenberg, Alexander L, Yang, Otto O   +11 more
core  

Empowerment or Engagement? Digital Health Technologies for Mental Healthcare [PDF]

, 2020
We argue that while digital health technologies (e.g. artificial intelligence, smartphones, and virtual reality) present significant opportunities for improving the delivery of healthcare, key concepts that are used to evaluate and understand their ...
A Nelson, A Sen, A Wardrope, ADI Kramer, AFT Winfield, B Friedman, BC Stahl, Christopher Burr, D Bakker, D Hausman, D Lupton, E Chiauzzi, EA Holm, EC Nelson, F Dzogang, F Greaves, F Starkey, G Spencer, J Garcia, J Owens, J Stilgoe, JA Hall, JJ Breedvelt, K Crawford, K Lehavot, KJ Roberts, L Edwards, L Floridi, L Floridi, L Floridi, L Floridi, L Floridi, L Floridi, M Ananny, M Durante, M D’Agostino, M Janssen, M Jirotka, M Sheehan, M Turilli, M-L Schermuly-Haupt, P Borah, P Nagy, R Andorno, R Binns, R Guidotti, R Kenny, R Kukla, RA Calvo, RD McMullan, SE Polykalas, SR Kamens, SR Paige, T Grisso, T Miller, Thomas Lansdall-Welfare, TL Beauchamp, W-W Zhao, WA Anthony, X Chen   +59 more
core   +1 more source