Results 31 to 40 of about 911,306 (169)

Effect of XlogP and hansen solubility parameters on the prediction of small molecule modified docetaxel, doxorubicin and irinotecan conjugates forming stable nanoparticles

Drug Delivery, 2021
Small molecule-chemotherapeutic drug conjugate nanoparticles (SMCDC NPs) has a great advantage in improving drug loading. However, the factors which influence these conjugates forming stable nanoparticles (NPs) are currently unclear.
Mei-Qi Xu, Ting Zhong, Xin Yao, Zhuo-Yue Li, Hui Li, Jing-Ru Wang, Zhen-Han Feng, Xuan Zhang   +7 more
doaj   +1 more source

Head‐to‐head comparison between ACQ and FRET in probing polymeric micelles

View
Environmentally responsive fluorophores, such as those with aggregation‐caused quenching (ACQ) and Förster resonance energy transfer (FRET) properties, are widely used to track nanocarriers while minimizing artifacts.
Runtong Zhang, Chang Liu, Ruonan Lu, Yuanmei Yang, Zichen Zhang, Yifan Cai, Haisheng He, Yi Lu, Aun Raza, Wei Wu   +9 more
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Kablosuz Ağlarda Yeni Bir Anahtar Dağıtım Yöntemi

Düzce Üniversitesi Bilim ve Teknoloji Dergisi, 2017
Ağ teknolojilerinin gelişimi ve dijital cihazların artışı multimedya iletimini hızlı ve kolay kılmıştır. Bununla birlikte açık haberleşme kanalları üzerinden yapılan dijital veri iletimi, telif hakkı ihlalleri, dolandırıcılık vb.
Çağatay Ay
doaj  

Advances in Medical Devices for Augmented Acupuncture Therapy

Advanced Science
Acupuncture, as a traditional medicine applied worldwide, is considered an effective treatment for numerous chronic diseases. Many researches have explored the biological mechanisms of acupuncture, including the skin‐neuro‐immune axis and inflammation ...
Ruisi Cai, Chenyi Yu, Xinyi Luo, Ningyu Xu, Jicheng Yu, Xiao Ye, Yuqi Zhang, Zhen Gu   +7 more
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PRONIOSOMES: A KEY TO IMPROVED DRUG DELIVERY

Journal of Drug Delivery and Therapeutics, 2014
In the recent years nanotechnology has brought revolutionary changes in the field of life sciences which includes novel drug delivery systems, diagnostics, nutraceuticals and biomedicals for implants and prosthesis. Sustained and Controlled release drug products are often formulated to permit the establishment and maintenance of drug concentration at ...
Rekha Kumari, Kuldeep Verma, Aatish Verma, Girish Kumar Yadav, Sheo Datta Maurya   +4 more
openaire   +2 more sources

Efficacy and safety of anti-prediabetic drugs in patients with prediabetes: a Bayesian network meta-analysis

BMC Medicine
Background Prediabetes refers to the transitional stage from normal glucose metabolism to diabetes. The International Diabetes Federation guidelines reported that, as of 2024, approximately 1.12 billion people globally were in the prediabetes stage ...
Yike Wu, Zihan Wang, Adili Tuersun, Qiuxia Yu, Yu Zhong, Shah Syed Alfakhar Ali, Haiyang Liu, Xinyi Hu, Yanfei Zhang, Liyuan Pang, Longzhou Li, Long Gao, Qiwen Wu, Shan Wang, Meng Cui, Linglu Sun, Yulin Wu, Antong Yin, Lei Zhang, Guo Ma   +19 more
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Biomimetic liposomes synergize with high-intensity focused ultrasound to induce ferroptosis in tumors

Acta Pharmaceutica Sinica B
The efficient targeted delivery and on-demand release of nanomedicines still present significant challenges in tumor therapy. In the present study, we developed a novel strategy of tumor ferroptosis therapy through the synergistic effect of nanomedicines
Ruizhe Xu, Xuejing Li, Xiaomin Su, Xifeng Qin, Ying He, Siyu Wang, Yue Liu, Jiayi Wu, Ting Wang, Mingyang Liu, Boshu Ouyang, Jia Li, Wuli Yang, Bo Zhang, Zhiqing Pang   +14 more
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Cerebralcare Granule® enhances memantine hydrochloride efficacy in APP/PS1 mice by ameliorating amyloid pathology and cognitive functions

Chinese Medicine, 2021
Background Alzheimer’s disease (AD) is a progressive neurodegenerative disease characterized by memory deficits and cognitive decline. Current drugs can only relieve symptoms, but cannot really cure AD. Cerebralcare Granule® (CG) is a Traditional Chinese
Ou Qiao, Xinyu Zhang, Yi Zhang, Haixia Ji, Zhi Li, Xiaoying Han, Wenzhe Wang, Xia Li, Juan Wang, Changxiao Liu, Wenyuan Gao   +10 more
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Role of size, surface charge, and PEGylated lipids of lipid nanoparticles (LNPs) on intramuscular delivery of mRNA

Journal of Nanobiotechnology
Lipid nanoparticles (LNPs) are currently the most commonly used non-viral gene delivery system. Their physiochemical attributes, encompassing size, charge and surface modifications, significantly affect their behaviors both in vivo and in vitro ...
Weiwen Kong, Yuning Wei, Zirong Dong, Wenjuan Liu, Jiaxin Zhao, Yan Huang, Jinlong Yang, Wei Wu, Haisheng He, Jianping Qi   +9 more
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MMP-2-triggered, mitochondria-targeted PROTAC-PDT therapy of breast cancer and brain metastases inhibition

Nature Communications
Proteolytic targeting chimera (PROTAC) technology is a protein-blocking technique and induces antitumor effects, with potential advantages. However, its effect is limited by insufficient distribution and accumulation in tumors.
Fan Tong, Yufan Wang, Yanyan Xu, Yang Zhou, Siqin He, Yufan Du, Wenqin Yang, Ting Lei, Yujun Song, Tao Gong, Huile Gao   +10 more
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