Results 21 to 30 of about 7,763,303 (316)

Near‐infrared fluorophores with absolute aggregation‐caused quenching and negligible fluorescence re‐illumination for in vivo bioimaging of nanocarriers

Aggregate, 2023
Environment‐responsive fluorophores with aggregation‐caused quenching (ACQ) properties have been applied to track nanocarriers with reduced artefacts caused by unbound or free fluorophores but suffer from incomplete fluorescence quenching and significant
Yifan Cai, Xin Ji, Yunsen Zhang, Chang Liu, Zichen Zhang, Yongjiu Lv, Xiaochun Dong, Haisheng He, Jianping Qi, Yi Lu, Defang Ouyang, Weili Zhao, Wei Wu   +12 more
doaj   +1 more source

Ionic co-aggregates (ICAs) based oral drug delivery: Solubilization and permeability improvement

Acta Pharmaceutica Sinica B, 2022
Due to the overwhelming percentage of poorly water-soluble drugs, pharmaceutical industry is in urgent need of efficient approaches for solubilization and permeability improvement.
Xianzi Zheng, Zhezheng Fang, Weizi Huang, Jianping Qi, Xiaochun Dong, Weili Zhao, Wei Wu, Yi Lu   +7 more
doaj   +1 more source

European Standard Clinical Practice Guideline and EXPeRT Recommendations for the Diagnosis and Management of Gastroenteropancreatic Neuroendocrine Neoplasms in Children and Adolescents

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric gastroenteropancreatic neuroendocrine neoplasms (GEP‐NENs) are extremely rare and clinically heterogeneous. Management has largely been extrapolated from adult practice. This European Standard Clinical Practice Guideline (ESCP), developed by the EXPeRT network in collaboration with adult NEN experts, provides (adult) evidence ...
Michaela Kuhlen, Calogero Virgone, Antje Redlich, Michael Abele, Ricardo Lopez‐Almaraz, Tal Ben‐Ami, Ewa Bien, Gianni Bisogno, Maja Mazic Cesen, Andrea Ferrari, Malgorzata A. Krawczyk, Yves Reguerre, Dominik T. Schneider, Ines B. Brecht, Charlotte Rigaud, Bilgehan Yalcin, Rainer Claus, Christian Vokuhl, Constantin Lapa, Jörg Fuchs, Segolene Hescot, Thomas Walter, Julien Hadoux, Daniel Orbach   +23 more
wiley   +1 more source

Improving service delivery in the public sector through strategic cost management: the case of a public private partnership in South Africa [PDF]

, 2012
Includes abstract.Includes bibliographical references.The key objective involved the research to discover how strategic cost management may improve service delivery.
Arendse, Kevin Brian
core   +1 more source

Hollow copper sulfide nanoparticles carrying ISRIB for the sensitized photothermal therapy of breast cancer and brain metastases through inhibiting stress granule formation and reprogramming tumor‐associated macrophages

Acta Pharmaceutica Sinica B, 2023
As known, the benefits of photothermal therapy (PTT) are greatly limited by the heat tolerance of cancer cells resulting from overexpressed heat shock proteins (HSPs). Then HSPs further trigger the formation of stress granules (SGs) that regulate protein
Fan Tong, Haili Hu, Yanyan Xu, Yang Zhou, Rou Xie, Ting Lei, Yufan Du, Wenqin Yang, Siqin He, Yuan Huang, Tao Gong, Huile Gao   +11 more
doaj   +1 more source

Commonwealth place-based service delivery initiatives: key learnings project [PDF]

, 2015
Overview: Place-based initiatives are programs designed and delivered with the intention of targeting a specific geographical location and particular population group in order to respond to complex social problems.
Julie Lahausse, Ben Edwards, Sez Wilks
core  

Evidence‐Informed Multidisciplinary Consensus Guidance for the Psychosocial Care of Adolescents With High‐Risk Cancer: Recommendations From the Italian Association of Pediatric Hematology and Oncology

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Adolescents with high‐risk cancer face complex developmental, psychosocial, and ethical challenges that extend beyond disease‐directed treatment. Although international recommendations exist for communication, psychosocial care, pediatric palliative care, survivorship, and shared decision‐making, these have largely evolved within ...
Johanna M. C. Blom, Dorella Scarponi, Giulia Zucchetti, Teresa Perillo, Maria Montanaro, Elisa Marconi, Chiara Rutigliano, Paolo Colavero, Paola Quarello, Marina Bertolotti, Monica Cellini, Carlo Clerici, Maurizio Mascarin, Francesca Bomben, Andrea Ferrari, the expert workgroup   +15 more
wiley   +1 more source

PRONIOSOMES: A KEY TO IMPROVED DRUG DELIVERY

Journal of Drug Delivery and Therapeutics, 2014
In the recent years nanotechnology has brought revolutionary changes in the field of life sciences which includes novel drug delivery systems, diagnostics, nutraceuticals and biomedicals for implants and prosthesis. Sustained and Controlled release drug products are often formulated to permit the establishment and maintenance of drug concentration at ...
Rekha Kumari, Kuldeep Verma, Aatish Verma, Girish Kumar Yadav, Sheo Datta Maurya   +4 more
openaire   +2 more sources

Guiding a Diclofenac Sodium Dual-Release Sustained Formulation Development Through In Vitro–In Vivo Relationship Based on Physiologically Based Pharmacokinetics

Pharmaceutics
Background: Dual-release sustained formulations enable rapid drug release for prompt therapeutic onset while retaining the characteristics of sustained-release dosage forms. However, due to the complexity of this dosage form, conventional trial-and-error
Qizheng Wang, Pengcheng Guo, Tianci Hu, Longjie Li, Tingxi Zhu, Yue Pan, Xiaoqiang Xiang, Jianxin Wang   +7 more
doaj   +1 more source

Mucoadhesive hydrogel microparticles based on poly (methacrylic acid-vinyl pyrrolidone)-chitosan for oral drug delivery

, 2011
The study was aimed at the evaluation of N-vinyl pyrrolidone (NVP) incorporated polymethacrylic acid-chitosan microparticles for oral drug delivery applications. Poly (methacrylic acid)-chitosan (PMC) and poly(methacrylic acid-vinyl pyrrolidone)-chitosan

core   +1 more source