Results 11 to 20 of about 2,783,643 (311)
Bioactive Materials, 2022 Compromised autophagy and defective lysosomal clearance significantly contribute to impaired neuronal proteostasis, which represents a hallmark of Alzheimer's disease (AD) and other age-related neurodegenerative disorders. Growing evidence has implicated
Shuting Xu +11 more
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In vivo dissolution of poorly water-soluble drugs: Proof of concept based on fluorescence bioimaging
Acta Pharmaceutica Sinica B, 2021 In vitro‒in vivo correlation (IVIVC) of solid dosage forms should be established basically between in vitro and in vivo dissolution of active pharmaceutical ingredients. Nevertheless, in vivo dissolution profiles have never been accurately portrayed. The
Yinqian Yang +9 more
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Influence of verapamil on the pharmacokinetics of rotundic acid in rats and its potential mechanism
Pharmaceutical Biology, 2021 Context Rotundic acid (RA), a plant-derived pentacyclic triterpene acid, has been reported to possess extensive pharmacological activities. The poor bioavailability limits its further development and potential clinic application. Objective To clarify the
Haihua Shang +7 more
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Therapies for epidermolysis bullosa: delivery is key [PDF]
British Journal of Dermatology, 2019 Linked Article: https://doi.org/10.1111/bjd.17075.
J. Bremer, P.C. Akker
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Novel Pharmaceutical Strategies for Enhancing Skin Penetration of Biomacromolecules
Pharmaceuticals, 2022 Skin delivery of biomacromolecules holds great advantages in the systemic and local treatment of multiple diseases. However, the densely packed stratum corneum and the tight junctions between keratinocytes stand as formidable skin barriers against the ...
Luyu Zhang +7 more
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Key skills by design: Adapting a central Web resource to departmental contexts [PDF]
, 2002 Web‐based delivery of support materials for students has proved to be a popular way of helping small teams to implement key skills policies within universities. The development of ‘key’ or ‘transferable’ skills is now encouraged throughout education, but
McAvinia, Claire
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Scavenger receptor A-mediated nanoparticles target M1 macrophages for acute liver injury
Asian Journal of Pharmaceutical Sciences, 2023 Acute liver injury (ALI) has an elevated fatality rate due to untimely and ineffective treatment. Although, schisandrin B (SchB) has been extensively used to treat diverse liver diseases, its therapeutic efficacy on ALI was limited due to its high ...
Rongping Zhang +10 more
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Implementing a resource list management system in an academic library [PDF]
, 2015 Purpose – The purpose of this paper is to review the key components of the introduction of a new resource list management system (RLMS) at Nottingham Trent University (NTU) using the Aspire application from Talis Education.
Cross, R
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Chinese Journal of Mechanical Engineering, 2022 The synchronizer is a key component of automatic mechanical transmission (AMT) equipped in electric vehicles, but the inertial lock-ring synchronizer (ILRS) commonly used there is not suitable especially for pure electric vehicles without a clutch ...
Lipeng Zhang +3 more
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Pharmaceutics, 2021 Oral propranolol hydrochloride has been the first-line treatment for infantile hemangioma (IH), whereas systemic exposure to propranolol has the potential of causing serious adverse reactions.
Jingjing He +6 more
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