Results 11 to 20 of about 999,964 (314)

PRONIOSOMES: A KEY TO IMPROVED DRUG DELIVERY

open access: yesJournal of Drug Delivery and Therapeutics, 2014
In the recent years nanotechnology has brought revolutionary changes in the field of life sciences which includes novel drug delivery systems, diagnostics, nutraceuticals and biomedicals for implants and prosthesis. Sustained and Controlled release drug products are often formulated to permit the establishment and maintenance of drug concentration at ...
Rekha Kumari   +4 more
openaire   +4 more sources

Engineering the drug carrier biointerface to overcome biological barriers to drug delivery [PDF]

open access: yes, 2020
Micro and nanoscale drug carriers must navigate through a plethora of dynamic biological systems prior to reaching their tissue or disease targets.
Finbloom, Joel A   +3 more
core   +1 more source

In vivo dissolution of poorly water-soluble drugs: Proof of concept based on fluorescence bioimaging

open access: yesActa Pharmaceutica Sinica B, 2021
In vitro‒in vivo correlation (IVIVC) of solid dosage forms should be established basically between in vitro and in vivo dissolution of active pharmaceutical ingredients. Nevertheless, in vivo dissolution profiles have never been accurately portrayed. The
Yinqian Yang   +9 more
doaj   +1 more source

Novel Pharmaceutical Strategies for Enhancing Skin Penetration of Biomacromolecules

open access: yesPharmaceuticals, 2022
Skin delivery of biomacromolecules holds great advantages in the systemic and local treatment of multiple diseases. However, the densely packed stratum corneum and the tight junctions between keratinocytes stand as formidable skin barriers against the ...
Luyu Zhang   +7 more
doaj   +1 more source

Scavenger receptor A-mediated nanoparticles target M1 macrophages for acute liver injury

open access: yesAsian Journal of Pharmaceutical Sciences, 2023
Acute liver injury (ALI) has an elevated fatality rate due to untimely and ineffective treatment. Although, schisandrin B (SchB) has been extensively used to treat diverse liver diseases, its therapeutic efficacy on ALI was limited due to its high ...
Rongping Zhang   +10 more
doaj   +1 more source

Polymeric Drug Delivery Systems by Additive Manufacturing

open access: yes, 2021
Additive manufacturing (AM) is gaining interests in drug delivery applications, offering innovative opportunities for the design and development of systems with complex geometry and programmed controlled release profile.
Borandeh, Sedigheh   +3 more
core   +1 more source

Design and Evaluation of Dissolving Microneedles for Enhanced Dermal Delivery of Propranolol Hydrochloride

open access: yesPharmaceutics, 2021
Oral propranolol hydrochloride has been the first-line treatment for infantile hemangioma (IH), whereas systemic exposure to propranolol has the potential of causing serious adverse reactions.
Jingjing He   +6 more
doaj   +1 more source

Defect Analysis and Innovation Design of Synchronizer for Clutchless Automatic Mechanical Transmission

open access: yesChinese Journal of Mechanical Engineering, 2022
The synchronizer is a key component of automatic mechanical transmission (AMT) equipped in electric vehicles, but the inertial lock-ring synchronizer (ILRS) commonly used there is not suitable especially for pure electric vehicles without a clutch ...
Lipeng Zhang   +3 more
doaj   +1 more source

Ionic co-aggregates (ICAs) based oral drug delivery: Solubilization and permeability improvement

open access: yesActa Pharmaceutica Sinica B, 2022
Due to the overwhelming percentage of poorly water-soluble drugs, pharmaceutical industry is in urgent need of efficient approaches for solubilization and permeability improvement.
Xianzi Zheng   +7 more
doaj   +1 more source

Strategic design of extracellular vesicle drug delivery systems [PDF]

open access: yes, 2018
Extracellular vesicles (EVs), sub-micron vectors used in intercellular communication, have demonstrated great promise as natural drug delivery systems. Recent reports have detailed impressive in vivo results from the administration of EVs pre-loaded with
Armstrong, JP, Stevens, MM
core   +1 more source

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