Results 121 to 130 of about 679,480 (310)

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

On forward secrecy in one-round key exchange

, 2011
Most one-round key exchange protocols provide only weak forward secrecy at best. \ud Furthermore, one-round protocols with strong forward secrecy often break badly when faced with an adversary who can obtain ephemeral keys.
Gonzalez Nieto, Juan M., Boyd, Colin, Colin Boyd, Juan González Nieto   +3 more
core   +1 more source

PDAKE: A Provably Secure PUF-Based Device Authenticated Key Exchange in Cloud Setting

IEEE Access, 2019
In this paper, we study on how to construct an authenticated key exchange protocol in a device based authentication setting where an user who has a PUF-based device and its multi-factor authenticators desires to mutually authenticate a server. Generally,
Jin Wook Byun
doaj   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

Implementing a secure key exchange protocol for openSSL

, 2018
Security models have been developed over time to examine the security of two-party authenticated key exchange protocols. In 2007, a reasonably strong security model for key exchange protocols has been proposed, namely extended Canetti-Krawczyk model (eCK
Alawatugoda, Janaka, Peiris, Nishen, Vivekaanathan, S, Wickramasinghe, Chamitha, Chuah, Chai Wen, Vivekaanathan, Seralathan, Wickramasinghe, C, Peiris, N, Wen, CC, Alawatugoda, J   +9 more
core   +1 more source

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

FEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn, Barbara Seroka, Ryszard Lazny, Zenon Lotowski, Thore Rohwerder   +4 more
wiley   +1 more source

A Method for Authentication and Key Exchange for Seamless Inter-domain Handovers

, 2004
- With the rapid growth of the Internet and mobile wireless technologies, an ever-increasing requirement on securing services between mobile users and access networks has become especially important.
Rene Soltwisch, Dieter Hogrefe, Xiaoming Fu, Seamless H, Internet Key Exchange   +4 more
core  

Leakage-Resilient Non-interactive Key Exchange in the Continuous-Memory Leakage Setting

, 2017
Recently, Chakraborty et al. (Cryptoeprint:2017:441) showed a novel approach of constructing several leakage-resilient cryptographic primitives by introducing a new primitive called leakage-resilient non-interactive key exchange (LR-NIKE).
Rangan, C Pandu, Alawatugoda, Janaka, Suvradip Chakraborty, Chakraborty, Suvradip, C. Pandu Rangan, Janaka Alawatugoda   +5 more
core   +1 more source

A secure and efficient authenticated key exchange scheme for smart grid. [PDF]

Heliyon, 2023
Xia Z, Liu T, Wang J, Chen S.
europepmc   +1 more source

Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains

FEBS Open Bio, EarlyView.
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth, Moritz Koch, Le‐Han Rössner, Johanna Eichhorn, Denys Pogoryelov, Matthias P. Mayer, Jude M. Przyborski   +6 more
wiley   +1 more source