Results 81 to 90 of about 361,970 (307)

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

FEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

A Practical Man-In-The-Middle Attack on Signal-Based Key Generation Protocols.

, 2012
Generating secret keys using physical properties of the wireless channel has recently become a popular research area. The main security assumption of these protocols is that a sufficiently distant adversary is unable to guess a generated secret due to ...
Martinovic, Ivan, Strohmeier, Martin, Matthias Wilhelm, Eberz, Simon, Eberz, S, Martin Strohmeier, Wilhelm, Matthias, Simon Eberz, Ivan Martinovic, Strohmeier, M, Wilhelm, M   +10 more
core   +2 more sources

On the Generalizations of Megrelishvili Protocol for Group Key Distribution

Indonesian Journal on Computing (Indo-JC), 2017
This article presents an extension of our previous research in <cite>AW17</cite> where we propose two variants of Megrelishvili key distribution schemes and investigate some of their elementary theoretical security analysis.
openaire   +2 more sources

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

FEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

Ciphertext Obfuscation-based Oblivious Transfer Protocol [PDF]

Jisuanji gongcheng
The Oblivious Transfer (OT) protocol is a privacy-preserving two-way communication protocol important for building secure multiparty computations. To exchange symmetric keys, this protocol is typically based on the Rivest—Shamir—Adleman (RSA) or Diffie ...
LI Xiaodong, ZHU Xiaopeng, ZHANG Jianyi, WU Yong, DOU Yimeng
doaj   +1 more source

Efficient non-malleable commitment schemes [PDF]

, 2000
We present efficient non-malleable commitment schemes based on standard assumptions such as RSA and Discrete-Log, and under the condition that the network provides publicly available RSA or Discrete-Log parameters generated by a trusted party.
Marc Fischlin, Fischlin, Roger, Roger Fischlin, Fischlin, Marc   +3 more
core   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

FEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas, Brigitta Maruzs, Zsófia E. Kálmán, Tomas Klumpler, Gyula Batta, Bálint Péterfia, Zoltán Gáspári   +6 more
wiley   +1 more source

Towards quantum-resistant cryptosystems from supersingular elliptic curve isogenies

Journal of Mathematical Cryptology, 2014
We present new candidates for quantum-resistant public-key cryptosystems based on the conjectured difficulty of finding isogenies between supersingular elliptic curves. The main technical idea in our scheme is that we transmit the images of torsion bases
De Feo Luca, Jao David, Plût Jérôme
doaj   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

FEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace, Alyssa Borges, Charles Arnaud, Tove Karlsson, Nina K. Bröker, Stefanie Barbirz, Marta Bally   +6 more
wiley   +1 more source