Results 41 to 50 of about 550,568 (326)

Development and application of smart key security control system for wind farms

open access: yesDianzi Jishu Yingyong, 2023
The informatization and intelligence of wind farm lock and key management is the key to further improve the level of wind farm operation and maintenance management.
Liu Hailong   +3 more
doaj   +1 more source

Photoactive Barbiturate Receptors:  An Ultimate Lock-and-Key System in Which the Key Unlocks the Lock [PDF]

open access: yesOrganic Letters, 2007
Conditional photofragmentation is achieved with binary systems incorporating the isophthaloyl bis-aminopyridine barbiturate recognition motif and dithiane- or trithiane-based photolabile modules, which cleave only in the presence of an external sensitizer.
Oleg D. Mitkin   +3 more
openaire   +3 more sources

Integrative analysis of circulating tumor cells (CTCs) and exosomes from small‐cell lung cancer (SCLC) patients: a comprehensive approach

open access: yesMolecular Oncology, EarlyView.
This study simultaneously investigated circulating tumor cells (CTCs) and exosomes from small‐cell lung cancer (SCLC) patients. The elevated expression of JUNB and CXCR4 in CTCs was a poor prognostic factor for SCLC patients, whereas exosomal overexpression of these biomarkers revealed a high discrimination ability of patients from healthy individuals,
Dimitrios Papakonstantinou   +13 more
wiley   +1 more source

Ship Lock Extraction from High-Resolution Remote Sensing Images Based on Fuzzy Theory and Prior Knowledge

open access: yesRemote Sensing
As crucial water conservancy projects, ship locks play a key role in flood control, shipping, water resource allocation, and promoting regional economic development, making them an indispensable part of the modern water transportation system.
Bingsun Chen   +9 more
doaj   +1 more source

Simple key locks turbine rotor blades [PDF]

open access: yes, 1966
Symmetrical, cruciform key has end tabs which bend up to lock tubine rotor blades against axial displacement.

core   +1 more source

Colloids with key-lock interactions: non-exponential relaxation, aging and anomalous diffusion

open access: yes, 2007
The dynamics of particles interacting by key-lock binding of attached biomolecules are studied theoretically. Experimental realizations of such systems include colloids grafted with complementary single-stranded DNA (ssDNA), and particles grafted with ...
Alexei V. Tkachenko   +3 more
core   +1 more source

The atypical KRASQ22K mutation directs TGF‐β response towards partial epithelial‐to‐mesenchymal transition in patient‐derived colorectal cancer tumoroids

open access: yesMolecular Oncology, EarlyView.
TGF‐β has a complex role in cancer, exhibiting both tumor‐suppressive and tumor‐promoting properties. Using a series of differentiated tumoroids, derived from different stages and mutational background of colorectal cancer patients, we replicate this duality of TGF‐β in vitro. Notably, the atypical but highly aggressive KRASQ22K mutation rendered early‐
Theresia Mair   +17 more
wiley   +1 more source

Heterogeneous and rate-dependent streptavidin-biotin unbinding revealed by high-speed force spectroscopy and atomistic simulations [PDF]

open access: yes, 2019
Receptor-ligand interactions are essential for biological function and their binding strength is commonly explained in terms of static lock-and-key models based on molecular complementarity.
Gonzalez, Laura   +4 more
core   +3 more sources

Simultaneous inhibition of TRIM24 and TRIM28 sensitises prostate cancer cells to antiandrogen therapy, decreasing VEGF signalling and angiogenesis

open access: yesMolecular Oncology, EarlyView.
TRIM24 and TRIM28 are androgen receptor (AR) coregulators which exhibit increased expression with cancer progression. Both TRIM24 and TRIM28 combine to influence the response of castrate‐resistant prostate cancer (CRPC) cells to AR inhibitors by mediating AR signalling, regulation of MYC and upregulating VEGF to promote angiogenesis. Castrate‐resistant
Damien A. Leach   +8 more
wiley   +1 more source

Silences in the boom: coal seam gas, neoliberalizing discourse, and the future of regional Australia

open access: yesJournal of Political Ecology, 2014
In high-stakes resource use struggles currently playing out across the world, different beliefs about economics and "growth-first" regional development underpin decisions and dynamics that have far-reaching consequences.
Alexandra Mercer   +2 more
doaj   +1 more source

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