Results 61 to 70 of about 6,515,199 (373)
Química Nova, 2005 In general, molecular modeling techniques applied in medicinal chemistry have been static and drug based. However the active site geometry and the intrinsic flexibility of both receptor and ligand are fundamental properties for molecular recognition and ...
Hugo Verli, Eliezer J. Barreiro
doaj +1 more source
Photoactive Barbiturate Receptors: An Ultimate Lock-and-Key System in Which the Key Unlocks the Lock [PDF]
Organic Letters, 2007 Conditional photofragmentation is achieved with binary systems incorporating the isophthaloyl bis-aminopyridine barbiturate recognition motif and dithiane- or trithiane-based photolabile modules, which cleave only in the presence of an external sensitizer.
Oleg D. Mitkin +3 more
openaire +3 more sources
, 2002 Quantitative predictions are presented of a depletion-induced torque and force acting on a single colloidal hard rod immersed in a solvent of hard spheres close to a planar hard wall. This torque and force, which are entirely of entropic origin, may play
A. Vrij +16 more
core +2 more sources
Quantum-classical correspondence in circularly polarized high harmonic generation [PDF]
, 2013 Using numerical simulations, we show that atomic high order harmonic generation, HHG, with a circularly polarized laser field offers an ideal framework for quantum-classical correspondence in strong field physics.
Bandrauk, A. D. +4 more
core +4 more sources
FEBS Letters, EarlyView.Cells must clear mislocalized or faulty proteins from membranes to survive. The AAA+ ATPase Msp1 performs this task, but dissecting how its six subunits work together is challenging. We engineered linked dimers with varied numbers of functional subunits to reveal how Msp1 subunits cooperate and use energy to extract proteins from the lipid bilayer ...
Deepika Gaur +5 more
wiley +1 more source
Remote SensingAs crucial water conservancy projects, ship locks play a key role in flood control, shipping, water resource allocation, and promoting regional economic development, making them an indispensable part of the modern water transportation system.
Bingsun Chen +9 more
doaj +1 more source
Portable appliance security apparatus [PDF]
, 1981 An apparatus for securing a small computer, or other portable appliance, against theft is described. It is comprised of a case having an open back through which the computer is installed or removed. Guide members in the form of slots are formed in a rear
Kerley, J. J.
core +1 more source
Lock cohorting: A general technique for designing NUMA locks [PDF]
, 2012 Multicore machines are quickly shifting to NUMA and CC-NUMA architectures, making scalable NUMA-aware locking algorithms, ones that take into account the machines' non-uniform memory and caching hierarchy, ever more important.
Dice, David +2 more
core +2 more sources
Experimental realization of the "lock-and-key" mechanism in liquid crystals. [PDF]
Soft Matter, 2016 The ability to control the movement and assembly of particles in liquid crystals is not only an important route to design functional materials, but also sheds light on the mechanisms of colloidal interactions.
Yimin Luo, F. Serra, K. Stebe
semanticscholar +1 more source
EMT‐associated bias in the Parsortix® system observed with pancreatic cancer cell lines
Molecular Oncology, EarlyView.The Parsortix® system was tested for CTC enrichment using pancreatic cancer cell lines with different EMT phenotypes. Spike‐in experiments showed lower recovery of mesenchymal‐like cells. This was confirmed with an EMT‐inducible breast cancer cell line.
Nele Vandenbussche +8 more
wiley +1 more source