PurposeTo assess and compare the effectiveness of magnetic resonance imaging (MRI) morphological features and MRI histogram analysis in noninvasively predicting Ki-67 expression levels in patients with IDH-wildtype glioblastoma.MethodsForty-six cases of ...
Qiang Liang +15 more
doaj +1 more source
Predictive Value of Tumor Ki-67 Expression in Two Randomized Trials of Adjuvant Chemoendocrine Therapy for Node-Negative Breast Cancer [PDF]
Several small studies have reported that having a high percentage of breast tumor cells that express the proliferation antigen Ki-67 (ie, a high Ki-67 labeling index) predicts better response to neoadjuvant chemotherapy.
Brown, R. W. +17 more
core
Active Learning‐Accelerated Discovery of Fibrous Hydrogels with Tissue‐Mimetic Viscoelasticity
Active learning accelerates the design of fibrous hydrogels that mimic the viscoelasticity of native tissues. By integrating multi‐objective optimization and closed‐loop experimentation, this approach efficiently identifies optimal formulations from thousands of possibilities and decouples elasticity and viscosity. The resulting hydrogels offer tunable
Zhengkun Chen +11 more
wiley +1 more source
Profil Pemeriksaan Indeks Proliferatif Ki-67 pada Penderita Kanker Payudara di RSUD Arifin Achmad Tahun 2010-201 [PDF]
Breast cancer is a Malignancy in breast tissue when cells grow abnormallyuncontrolled and invade to other parts of the body. Some biomarkers that already recognizedin breast cancer are Estrogen Receptor (ER), Progesterone Receptor (PR), HumanEpidermal ...
Fidiawati, W. A. (Wiwit) +2 more
core
Comparative histological and immunohistochemical study of ameloblastomas and ameloblastic carcinomas [PDF]
This study aimed to compare the histological and immunohistochemical characteristics of ameloblastomas (AM) and ameloblastic carcinomas (AC). Fifteen cases of AM and 9 AC were submitted to hematoxilin and eosin and immunohistochemical analysis with the ...
Aldape Barrios, B. +7 more
core +1 more source
We describe a microfluidic tumor‐stroma co‐culture model, engineered to resist collagen‐hydrogel contraction driven by fibroblast activity. Surface silanization with APTES covalently anchors the matrix to the chip, while Genipin crosslinking progressively increases stiffness and elasticity without harming cells. This supports >10 days of co‐culture and
Doriane Le Manach +4 more
wiley +1 more source
Markers expression of cell proliferation and apoptosis in basal cell carcinoma [PDF]
FUNDAMENTOS: O carcinoma basocelular é o câncer mais comum em humanos. Estudos que utilizam recursos da biologia molecular e genética, associados à histomorfologia, permitem a identificação de fatores de risco no desenvolvimento de lesões mais ...
CORRÊA, Marília de Pádua Dornelas +4 more
core +4 more sources
Multidimensional Cellular Micro‐Compartments to Model Invasive Lobular Carcinoma Dormancy
Invasive lobular carcinoma (ILC) is an understudied subtype of breast cancer that is susceptible to late recurrences. In this study, micro‐compartmentalization techniques spanning multiple dimensions, including 2D, pseudo‐3D, and 3D, are integrated to uncover the mechanisms underlying ILC dormancy, revealing the central role of p27Kip1.
Xilal Y. Rima +15 more
wiley +1 more source
The effects of androgen therapy on the endometrium of transgender men [PDF]
Individuals who identify themselves as transgender have gender identities that do not match their anatomical sex. Females who identify as male, also known as female-to-male transgender (FTM), may opt to undergo hormonal and surgical treatment in order to
Shah, Anita
core
Effects of different tamoxifen doses on mammary epithelium proliferation [PDF]
PURPOSE: to quantitatively analyze the immunoreaction of monoclonal antibody Ki-67 in the mammary epithelium adjacent to fibroadenoma of premenopausal women treated with tamoxifen, for 50 days, at doses of 5, 10 and 20 mg/day.
Baracat, Edmund Chada +3 more
core +3 more sources

