Results 121 to 130 of about 233,700 (287)

A Superhydrophobic 3D Cell Culture System Reveals the Mechanobiological Role of Cancer‐Associated Fibroblasts in Prostate Cancer Metastasis

Advanced Healthcare Materials, EarlyView.
A superhydrophobic 3D cell culture platform enables rapid and consistent formation of heterotypic tumor–stroma clusters, and reveals how physiological shear conditions influence metastatic signaling. Mechanical stimulation of cancer‐associated fibroblasts promotes sustained cytokine secretion and survival‐promoting pathways, showing how multicellular ...
Alexandria T. Carter, Abigail R. Fabiano, Ehsan Aalaei, Jason Deng, Dakota E. Rostant, Michael R. King   +5 more
wiley   +1 more source

Factores influyentes en el tiempo hasta la progresión bioquímica después de prostatectomía radical [PDF]

, 2011
INTRODUCTION: We assessed the time-influencing clinical-pathological factors for biochemical progression of an equal series of patients from a single institution.
Barba, J. (Joaquín), Berian-Polo, J.M. (José María), Brugarolas, X. (X.), Pascual-Piedrola, J.I. (Juan Ignacio), Rincon-Mayans, A. (Anibal), Robles-Garcia, J.E. (José Enrique), Romero-Vargas, L. (Luis), Rosell, D. (David), Tolosa-Eizaguirre, E. (Egoitz), Zudaire, J.J. (Juan Javier)   +9 more
core   +1 more source

3D Soft Hydrogels Induce Human Mesenchymal Stem Cells “Deep” Quiescence

Advanced Healthcare Materials, EarlyView.
Three‐dimensional soft hydrogels mimicking the bone marrow niche induce deep quiescence in human mesenchymal stem cells. Unlike 2D culture, 3D matrices halt proliferation, regulate cell‐cycle and quiescence markers, and downregulate mTORC1 signaling, preserving stem cell phenotype and therapeutic potential ex vivo.
David Boaventura Gomes, Timo Rademakers, Ana Filipa Henriques Lourenço, Andrea Calore, Clarissa Tomasina, Denis van Beurden, Jinjie Venema, Bryan Chömpff, Hong Liu, Nicole Bouvy, Sandra Camarero‐Espinosa, Lorenzo Moroni   +11 more
wiley   +1 more source

The characteristics of expression proliferation markers in endometrial hyperplasia

Гинекология, 2013
Objective. Determination of the mRNA expression genes of cell proliferation and tumor suppressor gene PTEN tumor growth in different types of endometrial hyperplasia and estimate the possibility of their use in clinical practice. Materials and methods. A
M R Dumanovskaya, G E Chernukha, O V Burmenskaya, O S Nepsha, S V Pavlovich, E A Kogan, D Yu Trofimov   +6 more
doaj  

3D‐Printed Piezoionic/Bioelectronic Hydrogel for Electro‐Metabolic Regulation of Osteogenic Differentiation

Advanced Healthcare Materials, EarlyView.
A 3D‐printed piezoionic GPMx hydrogel enables stable electromechanical signal generation under mechanical loading, exhibiting long‐term durability and low fatigue. As a bioactive patch, it restores endogenous bioelectricity to stimulate osteogenesis via Ca2+ influx and mitochondrial activation, while simultaneously enabling label‐free alkaline ...
Sayan Deb Dutta, Myoung Joon Jeon, Youjin Seol, Ki‐Taek Lim   +3 more
wiley   +1 more source

The association between Ki-67 expression and survival in breast cancer subtypes: a cross-sectional study of Ki-67 cut-point in northern Thailand

BMC Cancer
Background Breast cancer is a major health concern worldwide, and Ki-67 level index is a prognostic factor that indicates tumor proliferation and predicts survival outcomes. However, the standard Ki 67 cut-off level varies between local laboratories, and
Phanchaporn Wongmaneerung, Imjai Chitapanarux, Patrinee Traisathit, Sukon Prasitwattanaseree, Wisanu Rottuntikarn, Areewan Somwangprasert, Chagkrit Ditsatham, Kirati Watcharachan, Pitchayaponne Klunklin, Wimrak Onchan   +9 more
doaj   +1 more source

Phase Engineering of Atomically Precise Nanoclusters (APNCs) of Gold and Beyond

Advanced Materials, EarlyView.
Engineering the structural phase of materials is of paramount importance for both fundamental research and practical applications. In this Review, we summarize the recent progress in controlling the phases of atomically precise nanoclusters (APNCs) of gold, silver and copper, as well as bimetallic systems. The phase‐enabled material properties of APNCs
Yitong Wang, Avirup Sardar, Weijie Ji, Zhongyu Liu, Rongchao Jin   +4 more
wiley   +1 more source

Chemically Doped Conductive Polymers for Wearable Health Monitoring

Advanced Materials Technologies, EarlyView.
Among conductive polymers, poly(3,4‐ethylenedioxythiophene):poly(styrenesulfonate) (PEDOT:PSS), polyaniline (PANI), and polypyrrole (PPy) are the most studied and applied. Chemical doping significantly boosts intrinsic conductivity and mechanical robustness.
Mengdi Zuo, Jian Song, Hong Hu, Le Zheng, Lei Zhang, Charles H. Lawrie   +5 more
wiley   +1 more source

Topography‐Regulated Screening Platform for Myoblast Contact Guidance

Advanced Materials Technologies, EarlyView.
This study develops a topography‐regulated screening platform (12 gradients in 96‐topography‐well plate) enabling analysis of skeletal muscle morphogenesis. The topography‐induced cell morphology changed, cell polarization, and myotube differentiation, establishing an evaluative framework for generating pathologically relevant myotube phenotypes to ...
Tianqi Feng, Torben A.B. van der Boon, Savannah Amy Haupt, Adam Jones, Yanjing Ji, Theo G. Van Kooten, Patrick van Rijn   +6 more
wiley   +1 more source

Cambios en la expresión de KI-67 en tumores odontogénicos queratoquísticos sometidos a tratamiento de descompresión determinado mediante inmunohistoquímica [PDF]

, 2012
84 p.INTRODUCCIÓN: el tumor odontogénico queratoquístico (TOQ) deriva de la lámina dental, tiene una delgada capa epitelial, sus células basales se distribuyen en empalizada con un núcleo polarizado, una delgada capa de paraqueratina, con presencia de ...
Reyes Olave, Pablo Salvador (Prof. Guía), Robles Fuentes, Patricio Andrés   +1 more
core