Results 181 to 190 of about 239,474 (338)

Ki-67-proliferaatioindeksin määritys aivokasvaimissa

, 2013
Aivokasvainten pahanlaatuisuuden luokittelussa arvioidaan kasvainten histologiaa ja molekyylipatologisia, ennen kaikkea immunohistokemiallisia määrityksiä, mm. solusyklin eri vaiheiden analyysiä (esimerkiksi MIB-1/Ki-67-indeksi). Ki-67-vasta-aine reagoi jakautuvien solujen tumien kanssa.
openaire   +1 more source

Decoding Human Placental Cellular and Molecular Responses to Obesity and Fetal Growth

Advanced Science, EarlyView.
Women with obesity often deliver large‐for‐gestational‐age (LGA) infants. Single‐nucleus RNA sequencing of term placenta reveals that hypoxia and TNF‐α signaling in syncytiotrophoblasts are featured in maternal obesity, but inflammatory signatures in Hofbauer cells and response to lipid or carbohydrate metabolism in fibroblasts are specific to LGA.
Hong Jiang, Emilie Derisoud, Denise Parreira, Nayere Taebnia, Paulo R. Jannig, Reza Zandi Shafagh, Allan Zhao, Congru Li, Macarena Ortiz, Manuel Alejandro Maliqueo, Elisabet Stener‐Victorin, Volker M. Lauschke, Qiaolin Deng   +12 more
wiley   +1 more source

Estimation of the Ki-67 Proliferation Marker Expression Level with Computer Vision Technology

, 2020
С. А. Котов, С. А. Мозеров, С. О. Старков   +2 more
openalex   +2 more sources

Balanced Expression of the Diiron Oxygenase BioE Is Essential for Biotin Homeostasis in Elizabethkingia meningoseptica

Advanced Science, EarlyView.
BioE is a new diiron oxygenase that catalyzes the conversion of long‐chain acyl groups into pimeloyl thioester, initiating biotin synthesis. The overexpression of EmBioE disrupts lipid metabolic homeostasis, requiring repressor BioL to maintain a balance between long‐chain fatty acids and biotin synthesis.
Meng Zhang, Ying‐ying Fu, Xiaoqiang Yang, Qiuying Qin, Xinyu Su, Jiaming Fang, Yanhua Kang, Qingwen He, Zhi Ruan, Yongchang Xu   +9 more
wiley   +1 more source

Purely Epidural Thoracic Meningioma With Elevated Ki-67 in a Postmenopausal Female With Prior Gynecologic Malignancies: A Case Report [PDF]

Ryan Lebens, Bayan Razzaq, John Servider, Robert S Kleyner, Maqsood Ahmed, Harry Mushlin   +5 more
openalex   +1 more source

Evaluation of Myocyte Proliferation in Alcoholic Cardiomyopathy: Telomerase Enzyme Activity (TERT) Compared with Ki-67 Expression [PDF]

, 2011
Meritxell Lluís, Joaquim Fernández‐Solà, Sergi Castellvı́-Bel, Emilio Sacanella, Ramón Estruch, Á Urbano-Márquez   +5 more
openalex   +1 more source

Rapid Microfluidic Drug Sensitivity Testing Within 5 Days Using Minimal Clinical Tumor Samples

Advanced Science, EarlyView.
This study develops the air‐punched fabrication approach for nanoliter‐scale microcavity arrays with ultra‐smooth microcavity surfaces, with which rapid formation and 3D culture of tumor cell spheroids from small numbers of cell samples, as well as high‐throughput drug sensitivity testing can be achieved within 5 days.
Yi‐Xue Chen, Yi Zhang, Yu‐Jie Yan, Meng‐Ting Zhang, Jian‐Bo Chen, Yi‐Rong Jiang, Jie Wu, Hui‐Feng Wang, Jian‐Zhang Pan, Zhi‐Gang Chen, Jian Huang, Qun Fang   +11 more
wiley   +1 more source

CT Radiomics Model for Predicting the Ki-67 Index of Lung Cancer： An Exploratory Study [PDF]

, 2021
Qing Fu, Shun li Liu, Da peng Hao, Ya Hu, Xue jun Liu, Zaixian Zhang, Wen hong Wang, Xiao Tang, Chuan yu Zhang, Shi He Liu, Shi he Liu, Shi he Liu   +11 more
openalex   +1 more source

CDK4/6 Inhibition Induces CD8+ T Cell Antitumor Immunity via MIF‐Induced Functional Orchestration of Tumor‐Associated Macrophages

Advanced Science, EarlyView.
CDK4/6 inhibition promotes CD8+ T cell expansion through tumor‐macrophage crosstalk by activating HIF‐1α and enhancing MIF‐CD44/CD74 signaling. This reprograms TAMs to boost MHC‐I antigen presentation, and CDK4/6 inhibitor‐trained M1 TAM supernatant therapy synergizes with low‐dose PD‐1 blockade to restore antitumor immunity.
Lin He, Yuzhong Peng, Lat‐lun Leong, Jingbo Zhou, Dongyang Tang, Weilu Wang, Xiaoran Wu, Josh haipeng Lei, Yongqin Ye, Yangyang Feng, Yunfeng Qiao, Xiangpeng Chu, Di Mu, Qi Zhao, Tzuming Liu, Yan Chen, Paul Kwonghang Tam, Chu‐Xia Deng   +17 more
wiley   +1 more source

Somatostatin analogs in neuroendocrine tumors with Ki-67 index of ≥10. [PDF]

J Neuroendocrinol
Braegelmann J, Mathew A, Schmidt B, Kalisch H, Fendler WP, Führer-Sakel D, Lahner H.   +6 more
europepmc   +1 more source