Results 1 to 10 of about 119,680 (164)

Outcome of breast cancer patients regarding obesity and complications: Analysis of risk factors [PDF]

Romanian Medical Journal, 2021
Introduction. Breast cancer is the leading cause of cancer death in Romania. In the context in which the treatments available for this pathology have increased curability, the identification of negative prognostic factors involved in the evolution of ...
Iuliana Pantelimon, Laurentia Nicoleta Gales, Maria Daniela Tanasescu, Irina Nita, Loredana Sabina Cornelia Manolescu, Rodica Maricela Anghel   +5 more
doaj   +1 more source

Differential challenges in salivary gland neoplasms [PDF]

Archives of Biological Sciences, 2021
Salivary gland tumors are neoplasms characterized by a high level of pleomorphism and histological overlap. One tumor may contain several cell types; therefore, it is necessary to include immunohistochemical staining, as well as morphometric analysis of ...
Živković Nikola, Kostić Miloš, Cvetanović Ana, Jovičić-Milentijević Maja, Spasić Milan, Petrović Milica, Trajković Miloš, Denčić Tijana, Krtinić Dane   +8 more
doaj   +1 more source

CT Radiomics for the Preoperative Prediction of Ki67 Index in Gastrointestinal Stromal Tumors: A Multi-Center Study

Frontiers in Oncology, 2021
PurposeThis study established and verified a radiomics model for the preoperative prediction of the Ki67 index of gastrointestinal stromal tumors (GISTs).Materials and MethodsA total of 344 patients with GISTs from three hospitals were divided into a ...
Yilei Zhao, Meibao Feng, Minhong Wang, Liang Zhang, Meirong Li, Chencui Huang   +5 more
doaj   +1 more source

Role of topoisomerase II α and Ki -67 biomarkers in pituitary tumors

Journal of Pathology of Nepal, 2023
Background: Pituitary Adenoma, a neoplastic proliferation of anterior pituitary hormone producing cells, is mainly considered benign but some are clinically aggressive and recurrent and very rarely malignant.
Chhanda Das, Madhumita Mukhopadhyay, Satinath Mukhopadhyay, Avijit Hazra   +3 more
doaj   +1 more source

An International Ki67 Reproducibility Study [PDF]

JNCI: Journal of the National Cancer Institute, 2013
In breast cancer, immunohistochemical assessment of proliferation using the marker Ki67 has potential use in both research and clinical management. However, lack of consistency across laboratories has limited Ki67's value. A working group was assembled to devise a strategy to harmonize Ki67 analysis and increase scoring concordance.
Polley M. -Y. C., Leung S. C. Y., McShane L. M., Gao D., Hugh J. C., Mastropasqua M. G., Viale G., Zabaglo L. A., Penault-Llorca F., Bartlett J. M. S., Gown A. M., Symmans W. F., Piper T., Mehl E., Enos R. A., Hayes D. F., Dowsett M., Nielsen T. O.   +17 more
openaire   +4 more sources

High Ki67 proliferation index but not cell-of-origin subtypes is associated with shorter overall survival in diffuse large B-cell lymphoma

Avicenna Journal of Medicine, 2020
Background: CD10, BCL6, and MUM1 are commonly used immunohistochemical stains for classifying diffuse large B-cell lymphoma (DLBCL), which is useful in predicting outcome.
Feras Zaiem, Rada Jerbi, Omar Albanyan, Jordyn Puccio, Zyad Kafri, Jay Yang, Ali M Gabali   +6 more
doaj   +1 more source

Neuronal deletion of phosphatase and tensin homolog in mice results in spatial dysregulation of adult hippocampal neurogenesis

Frontiers in Molecular Neuroscience, 2023
Adult neurogenesis is a persistent phenomenon in mammals that occurs in select brain structures in both healthy and diseased brains. The tumor suppressor gene, phosphatase and tensin homolog deleted on chromosome 10 (Pten) has previously been found to ...
Sarah E. Latchney, Brayan R. Ruiz Lopez, Paige D. Womble, Katherine J. Blandin, Joaquin N. Lugo   +4 more
doaj   +1 more source

STAT3 Expression and Correlation Between Ki-67 and PHH3 in Meningiomas: Is it Possible to Predict Recurrence?

Düzce Tıp Fakültesi Dergisi, 2022
Aim: The aim of this study was to investigate the correlation between PHH3 and ki-67 labeling index, and the association of STAT3 expression with mitotic index, grade by World Health Organization 2016 classification, and clinicopathological features of ...
Sinem Kantarcıoğlu Coşkun, Güven Kılıç   +1 more
doaj   +1 more source

Correlation Analysis of Ki67 Expression and EGFR Mutation on the Risk of Recurrence and Metastasis in Postoperative Patients with Stage I Lung Adenocarcinoma

Chinese Journal of Lung Cancer, 2022
Background and objective The prognosis of stage I non-small cell lung cancer (NSCLC) is generally good. However, some of the stage I NSCLC patients still may have early recurrence and metastasis, and there is no standard method to screen this part of the
Lili XU, Renhua GUO
doaj   +1 more source

RET mutated C-cells proliferate more rapidly than non-mutated neoplastic cells

Endocrine Connections, 2021
A statistically significant higher prevalence of the RET p.Met918Thr somatic mutation, identified by direct sequencing, was previously reported in MTC > 2 cm than in smaller tumors. Aim of this study was to correlate the full RET and RAS mutation profile,
Cristina Romei, Teresa Ramone, Chiara Mulè, Alessandro Prete, Virginia Cappagli, Loredana Lorusso, Liborio Torregrossa, Fulvio Basolo, Raffaele Ciampi, Rossella Elisei   +9 more
doaj   +1 more source