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Outcome of breast cancer patients regarding obesity and complications: Analysis of risk factors [PDF]

open access: yesRomanian Medical Journal, 2021
Introduction. Breast cancer is the leading cause of cancer death in Romania. In the context in which the treatments available for this pathology have increased curability, the identification of negative prognostic factors involved in the evolution of ...
Iuliana Pantelimon   +5 more
doaj   +1 more source

Differential challenges in salivary gland neoplasms [PDF]

open access: yesArchives of Biological Sciences, 2021
Salivary gland tumors are neoplasms characterized by a high level of pleomorphism and histological overlap. One tumor may contain several cell types; therefore, it is necessary to include immunohistochemical staining, as well as morphometric analysis of ...
Živković Nikola   +8 more
doaj   +1 more source

CT Radiomics for the Preoperative Prediction of Ki67 Index in Gastrointestinal Stromal Tumors: A Multi-Center Study

open access: yesFrontiers in Oncology, 2021
PurposeThis study established and verified a radiomics model for the preoperative prediction of the Ki67 index of gastrointestinal stromal tumors (GISTs).Materials and MethodsA total of 344 patients with GISTs from three hospitals were divided into a ...
Yilei Zhao   +5 more
doaj   +1 more source

Role of topoisomerase II α and Ki -67 biomarkers in pituitary tumors

open access: yesJournal of Pathology of Nepal, 2023
Background: Pituitary Adenoma, a neoplastic proliferation of anterior pituitary hormone producing cells, is mainly considered benign but some are clinically aggressive and recurrent and very rarely malignant.
Chhanda Das   +3 more
doaj   +1 more source

An International Ki67 Reproducibility Study [PDF]

open access: yesJNCI: Journal of the National Cancer Institute, 2013
In breast cancer, immunohistochemical assessment of proliferation using the marker Ki67 has potential use in both research and clinical management. However, lack of consistency across laboratories has limited Ki67's value. A working group was assembled to devise a strategy to harmonize Ki67 analysis and increase scoring concordance.
M. C. Polley   +17 more
openaire   +4 more sources

High Ki67 proliferation index but not cell-of-origin subtypes is associated with shorter overall survival in diffuse large B-cell lymphoma

open access: yesAvicenna Journal of Medicine, 2020
Background: CD10, BCL6, and MUM1 are commonly used immunohistochemical stains for classifying diffuse large B-cell lymphoma (DLBCL), which is useful in predicting outcome.
Feras Zaiem   +6 more
doaj   +1 more source

Neuronal deletion of phosphatase and tensin homolog in mice results in spatial dysregulation of adult hippocampal neurogenesis

open access: yesFrontiers in Molecular Neuroscience, 2023
Adult neurogenesis is a persistent phenomenon in mammals that occurs in select brain structures in both healthy and diseased brains. The tumor suppressor gene, phosphatase and tensin homolog deleted on chromosome 10 (Pten) has previously been found to ...
Sarah E. Latchney   +4 more
doaj   +1 more source

Immunophenotype of Atypical Polypoid Adenomyoma of the Uterus: Diagnostic Value and Insight on Pathogenesis [PDF]

open access: yes, 2020
Atypical polypoid adenomyoma (APA) is a rare uterine lesion constituted by atypical endometrioid glands, squamous morules, and myofibromatous stroma. We aimed to assess the immunophenotype of the 3 components of APA, with regard to its pathogenesis and ...
Aggarwal   +46 more
core   +1 more source

STAT3 Expression and Correlation Between Ki-67 and PHH3 in Meningiomas: Is it Possible to Predict Recurrence?

open access: yesDüzce Tıp Fakültesi Dergisi, 2022
Aim: The aim of this study was to investigate the correlation between PHH3 and ki-67 labeling index, and the association of STAT3 expression with mitotic index, grade by World Health Organization 2016 classification, and clinicopathological features of ...
Sinem Kantarcıoğlu Coşkun   +1 more
doaj   +1 more source

Correlation Analysis of Ki67 Expression and EGFR Mutation on the Risk of Recurrence and Metastasis in Postoperative Patients with Stage I Lung Adenocarcinoma

open access: yesChinese Journal of Lung Cancer, 2022
Background and objective The prognosis of stage I non-small cell lung cancer (NSCLC) is generally good. However, some of the stage I NSCLC patients still may have early recurrence and metastasis, and there is no standard method to screen this part of the
Lili XU, Renhua GUO
doaj   +1 more source

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