Results 21 to 30 of about 119,779 (263)

Cell kinetic markers in cutaneous squamous and basal cell carcinoma of the head and neck

Brazilian Journal of Otorhinolaryngology, 2022
Introduction: Proliferation markers play a significant role in the biologic behavior of tumors. Geminin is a known inhibitor of the cell cycle and DNA replication and has not been previously reported in cutaneous basal and squamous cell carcinomas of the
Mojgan Alaeddini, Shahroo Etemad-Moghadam   +1 more
doaj   +1 more source

Addition of carboplatin-gemcitabine as second-line neoadjuvant chemotherapy in non-responsive locally advanced breast cancer patients to standard neoadjuvant chemotherapy and evaluation of factors affecting response: a randomized controlled trial

BMC Cancer, 2021
Background Neoadjuvant chemotherapy (NACT) is the prime approach to the management of locally advanced breast cancer (LABC). Influenced by different factors such as pathologic tumor characteristics, hormone receptor status, HER2 and proliferation marker ...
Dena Firouzabadi, Amirreza Dehghanian, Alireza Rezvani, Laleh Mahmoudi, Abdolrasoul Talei   +4 more
doaj   +1 more source

Low correlation between Ki67 assessed by qRT-PCR in Oncotype Dx score and Ki67 assessed by Immunohistochemistry [PDF]

Scientific Reports, 2022
AbstractBreast cancers expressing high levels of Ki67 are associated with poor outcomes. Oncotype DX test was designed for ER+/HER2− early-stage breast cancers to help adjuvant chemotherapy decision by providing a Recurrent Score (RS). RS measures the expression of 21 specific genes from tumor tissue, including Ki67.
Selmani, Zohair, Molimard, Chloé, Overs, Alexis, Bazan, Fernando, Chaigneau, Loic, Dobi, Erion, Meneveau, Nathalie, Mansi, Laura, Paillard, Marie-Justine, Meynard, Guillaume, Viot, Julien, Algros, Marie-Paule, Borg, Christophe, Feugeas, Jean-Paul, Pivot, Xavier, Prétet, Jean-Luc, Curtit, Elsa   +16 more
openaire   +5 more sources

A study on molecular subtype of breast carcinoma using ER, HER2, PR, and its relation with Ki67 [PDF]

Journal of Clinical and Basic Research, 2023
Background: Using molecular biomarkers of breast cancer (BC) receives optimal treatment. Established biomarkers like estrogen receptor (ER), progesterone receptor (PR), HER2, and Ki67 may play significant roles in the sub-categorization of BC to predict ...
Haricharan BV, Shilpa Karamchedu, Rasheed Fatima, Shaik Nazeer, Fatima ., Sagarika D, Suresh K, Florence Nightingale   +7 more
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Analysis of Factors Related to Lymph Node Metastasis in Early-Stage Type 1 Endometrial Cancer: Verifying the Clinical Value of Positive Threshold of the Immunohistochemical Parameter Ki67

Cancer Management and Research, 2021
Peng Jiang, Rui Yuan Department of Gynecology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, People’s Republic of ChinaCorrespondence: Rui YuanDepartment of Gynecology, The First Affiliated Hospital of Chongqing Medical ...
Jiang P, Yuan R
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ki67 nuclei detection and ki67-index estimation: a novel automatic approach based on human vision modeling [PDF]

BMC Bioinformatics, 2019
Abstract Background The protein ki67 (pki67) is a marker of tumor aggressiveness, and its expression has been proven to be useful in the prognostic and predictive evaluation of several types of tumors. To numerically quantify the pki67 presence in cancerous tissue areas, pathologists generally analyze histochemical ...
Barricelli B. R., Casiraghi E., Gliozzo J., Huber V., Leone B. E., Rizzi A., Vergani B.   +6 more
openaire   +4 more sources

Correlations Between Oncotype DX Recurrence Score and Classic Risk Factors in Early Breast Cancer: Results of A Prospective Multicenter Study in Turkey

European Journal of Breast Health, 2016
Objective: Breast cancer is the most common malignancy among Turkish women and the rate of early stage disease is increasing. The Oncotype DX 21-gene assay is predictive of distant recurrence in ER-positive, HER2-negative early breast cancer. We aimed to
Vahit Özmen, Ajlan Atasoy, Erhan Gökmen, Mustafa Özdoğan, Nilufer Güler, Cihan Uras, Engin Ok, Orhan Demircan, Abdurrahman Işıkkdoğan, Neslihan Cabioğlu, Fatma Şen, Pınar Saip   +11 more
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Clinical and anamnestic risk factors for the development of uterine leiomyoma in women of reproductive age: A case control study

Гинекология, 2023
Aim. To identify risk factors for uterine leiomyoma (ULM) in women of reproductive age based on the study of clinical and medical history features in various tumor types. Materials and methods.
Darya A. Malyshkina, Nataliya Yu. Sotnikova, Dmitriy N. Voronin, Arina E. Kalinina, Elizaveta M. Godunova, Maria V. Golubeva, Elizaveta V. Rumyanceva   +6 more
doaj   +1 more source

The Effect of 5-Fluorouracil on the Tongue Mucosa of Adult Male Albino Rat and the Possible Protective Role of Melatonin: A Light and Scanning Electron Microscopic Study [PDF]

The Egyptian Journal of Histology, 2021
Background: 5-Fluorouracil (5-FU) is a common anti-tumor drug that is used in the management of different forms of malignancies. Mucosal inflammation of the oral cavity is the most common adverse effect of its administration.
Amany Shalaby, Shaimaa Kashef
doaj   +1 more source

Role of expression of p53 and Ki67 in the progression of Wilms tumor: Correlation with patients’ survival [PDF]

Egyptian Journal of Cancer and Biomedical Research, 2021
Background: Wilms tumor (WT) is the most frequent renal tumor of childhood and is a highly responsive tumor to chemotherapy. P53 and ki67 are two of the most important markers that have been evaluated in many cancers.
Ahmad Darwish, Doaa Alemam, Heba Sheta
doaj   +1 more source