Results 1 to 10 of about 1,052 (92)

Experimentally induced puromycine aminonucleoside nephrosis (PAN) in rats: evaluation of angiogenic protein platelet-derived endothelial cell growth factor (PD-ECGF) expression in glomeruli [PDF]

Journal of Biomedical Science, 2012
Background In experimentally induced puromycine aminonucleoside nephrosis (PAN) animal models, nephrotic syndrome with minimal change disease and focal and segmental sclerosis-like nephritis similar to that in human is demonstrated; however, the real ...
Seckin Ismail, Uzunalan Mumin, Pekpak Meltem, Kokturk Sibel, Sonmez Huseyin, Öztürk Zeynep, Demirci Sibel, Yaprak Elif   +7 more
doaj   +2 more sources

Expression of Platelet-Derived Endothelial Cell Growth Factor (PD-ECGF) and Its mRNA in Uterine Cervical Cancers [PDF]

British Journal of Cancer, 1999
Reiko Hirose, T Tamaya, J Fujimoto
exaly   +2 more sources

Anti-Metastatic and Anti-Angiogenic Effects of Curcumin Analog DK1 on Human Osteosarcoma Cells In Vitro

Pharmaceuticals, 2021
Osteosarcoma (OS) is a life-threatening malignant bone tumor associated with poor prognosis among children. The survival rate of the patient is still arguably low even with intensive treatment provided, plus with the inherent side effects from the ...
Muhammad Nazirul Mubin Aziz, Nurul Fattin Che Rahim, Yazmin Hussin, Swee Keong Yeap, Mas Jaffri Masarudin, Nurul Elyani Mohamad, Muhammad Nadeem Akhtar, Mohd Azuraidi Osman, Yoke Kqueen Cheah, Noorjahan Banu Alitheen   +9 more
doaj   +1 more source

Distinct substrate specificity and physicochemical characterization of native human hepatic thymidine phosphorylase. [PDF]

PLoS ONE, 2018
Thymidine phosphorylase (TP; EC 2.4.2.4) is involved regulation of intra- or extracellular thymidine concentration, angiogenesis, cancer chemotherapy, radiotherapy, as well as tumor imaging.
Taesung Oh, Mahmoud H El Kouni
doaj   +1 more source

Angiogenic content of microparticles in patients with diabetes and coronary artery disease predicts networks of endothelial dysfunction

Cardiovascular Diabetology, 2022
Background Elevated endothelial microparticles (EMPs) levels are surrogate markers of vascular dysfunction. We analyzed EMPs with apoptotic characteristics and assessed the angiogenic contents of microparticles in the blood of patients with type 2 ...
Isra Marei, Omar Chidiac, Binitha Thomas, Jennifer Pasquier, Soha Dargham, Amal Robay, Muneera Vakayil, Mohammad Jameesh, Christopher Triggle, Arash Rafii, Amin Jayyousi, Jassim Al Suwaidi, Charbel Abi Khalil   +12 more
doaj   +1 more source

The cytosol activity of thymidine phosphorylase in endometrial cancer

Journal of Experimental & Clinical Cancer Research, 2008
Background Thymidine phosphorylase (TP) is identical with platelet-derived endothelial cell growth factor (PD-ECGF) which promotes angiogenesis. The aim of this study was to evaluate the cytosol activity of TP in tumor samples from patients with ...
Bieńkiewicz Andrzej, Kubiak Robert, Miszczak-Zaborska Elżbieta, Bartkowiak Jacek   +3 more
doaj   +1 more source

Angiogenic biomarkers in children with congenital heart disease: possible implications

Italian Journal of Pediatrics, 2010
Background Vascular endothelial growth factor (VEGF), platelet derived endothelial cell growth factor/thymidine phosphorylase (PD-ECGF/TP) and leptin are known as potent angiogenic factors The objective of the study was to evaluate these angiogenic ...
Mohamed Nagwa A, El-Melegy Nagla T
doaj   +1 more source

CLINICAL AND MORPHOLOGICAL CHARACTERISTICS AND PROGNOSTIC SIGNIFICANCE OF THE CONTENTS OF PD-ECGF, TGF-β, KI67 IN ENDOMETRIUM AT LARGE UTERINE LEIOMYOMA

Клиническая практика, 2016
The endometrium may be the most convenient object of forecasting the development of the large uterine fibroid, as the object is available in the diagnosis of diseases of the uterus, changes in its cytokine profile linked with the growth of uterine ...
S I Askolskaya, E A Kogan, Yu V Popov, M A Solomakhina, N M Fayzullina   +4 more
doaj   +1 more source

LARGE UTERINE LEIOMYOMAS: PATHOGENETIC MECHANISMS OF GROWTH

Клиническая практика, 2016
The pathogenesis of uterine fibroids remains controversial and raises many questions. The causes and mechanism of development of large leiomyoma are unknown.
E A Kogan, S I Askolskaya, Yu V Popov, M A Solomakhina, N M Fayzullina   +4 more
doaj   +1 more source

Natural compounds as angiogenic enzyme thymidine phosphorylase inhibitors: In vitro biochemical inhibition, mechanistic, and in silico modeling studies.

PLoS ONE, 2019
Natural flora is the richest source of novel therapeutic agents due to their immense chemical diversity and novel biological properties. In this regard, eighteen natural products belonging to different chemical classes were evaluated for their thymidine ...
Sumaira Javaid, Muniza Shaikh, Narjis Fatima, M Iqbal Choudhary   +3 more
doaj   +1 more source