Results 31 to 40 of about 119,779 (263)

Preserving dense features for Ki67 nuclei detection

Medical Imaging 2022: Digital and Computational Pathology, 2022
Published in SPIE Medical Imaging 04/2022: Digital and Computational Pathology; 120390Y.
Seyed Hossein Mirjahanmardi, Melanie Dawe, Anthony Fyles, Wei Shi, Fei-Fei Liu, Susan Done, April Khademi   +6 more
openaire   +2 more sources

A prognostic prediction model for advanced gastric cancer based on Ki67

Zhongguo linchuang yanjiu
Objective To establish and validate a nomogram model for predicting the prognosis of advanced gastric cancer based on Ki67 expression，and to explore effect of different levels of Ki67 on progression free survival（PFS）in the same patient with different ...
NIU Linjun*，LI Xinzhong，LYU Yongjian
doaj   +1 more source

Loss of expression of claudin-1 in psoriasis is associated with proliferative state of keratinocytes

Indian Journal of Dermatopathology and Diagnostic Dermatology, 2020
Background: Psoriasis is a chronic remitting and relapsing inflammatory disease, with a prevalence of 0.44%–2.5% and is characterized by T-cell-mediated rapid turnover of epithelial cells.
Manoj Gopal Madakshira, Bishan Dass Radotra, Uma Nahar Saikia   +2 more
doaj   +1 more source

The Proper Ki-67 Cut-Off in Hormone Responsive Breast Cancer: A Monoinstitutional Analysis with Long-Term Follow-Up

Breast Cancer: Targets and Therapy, 2021
Augusto Lombardi, Rachele Lazzeroni, Laura Bersigotti, Valeria Vitale, Claudio Amanti Department of Breast Surgery, Università di Roma La Sapienza – OspedaleSant’Andrea, Rome, ItalyCorrespondence: Laura BersigottiOspedaleSant&rsquo ...
Lombardi A, Lazzeroni R, Bersigotti L, Vitale V, Amanti C   +4 more
doaj  

Clinical efficacy and mechanism for focused ultrasound (FUS) in the management of cervical intraepithelial neoplasia 1 (CIN1)

International Journal of Hyperthermia, 2020
Objective This study was aimed at investigating the clinical efficacy and studying the possible mechanism of FUS applications to treat cervical intraepithelial neoplasia 1 (CIN1).
Zhenhua Fu, Yijin Fan, Can Wu, Ping Yan, Yibi Ye, Huan Yang, Chengzhi Li   +6 more
doaj   +1 more source

Analysis of the prognostic survival of Ki67, CEA, CA199 and relevant clinical pathological features in metastatic colorectal cancer

结直肠肛门外科, 2023
[Objectives] To analyze the relationship between Ki67, CEA, CA199, and relevant clinical pathological features and the prognostic survival of metastatic colorectal cancer (mCRC).
Huang Jian, Fan Yufang, Chen Yuemiao, Huang Lifeng, Cai Xiaoping   +4 more
doaj   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

The proliferation marker Ki67, but not neuroendocrine expression, is an independent factor in the prediction of prognosis of primary prostate cancer patients

Radiology and Oncology, 2016
Neuroendocrine markers, which could indicate for aggressive variants of prostate cancer and Ki67 (a well-known marker in oncology for defining tumor proliferation), have already been associated with clinical outcome in prostate cancer.
Pascale Mariarosa, Aversa Cinzia, Barbazza Renzo, Marongiu Barbara, Siracusano Salvatore, Stoffel Flavio, Sulfaro Sando, Roggero Enrico, Bonin Serena, Stanta Giorgio   +9 more
doaj   +1 more source

MITF maintains genome stability in nonmelanocyte lineages

Molecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir, Adrián López García de Lomana, Thejus B. Venkatesh, Kritika Kirty, Snaevar Sigurdsson, Linda Vidarsdottir, Ramile Dilshat, Erla Sveinbjornsdottir, Snaedis Ragnarsdottir, Daniel H Magnusson, Maria R. Bustos, Eirikur Steingrimsson, Thorkell Gudjonsson, Stefan Sigurdsson   +13 more
wiley   +1 more source