Results 11 to 20 of about 119,779 (263)

Novel Monoclonal Antibodies Specific for Human Ki67 and P53 Tumor Markers in Breast Cancer Tissue Samples [PDF]

Iranian Journal of Immunology, 2023
Background: Ki67 and P53 are important diagnostic and prognostic biomarkers expressed in several cancers. The current standard method for evaluating Ki67 and P53 in cancer tissues is immunohistochemistry (IHC), and having highly sensitive monoclonal ...
Masoud Hassanzadeh Makoui, Maryam Mobini, Jalal Khoshnoodi, Tannaz Bahadori, Forough Golsaz-Shirazi, Hedieh Moradi Tabriz, Zahra Madjd, Mahmood Jeddi-Tehrani, Amir-Hassan Zarnani, Mohammad Mehdi Amiri, Fazel Shokri   +10 more
doaj   +1 more source

p62 Is a Potential Biomarker for Risk of Malignant Transformation of Oral Potentially Malignant Disorders (OPMDs)

Current Issues in Molecular Biology, 2023
To determine the intracellular behavior of p62, a marker of selective autophagy, in oral potentially malignant disorders (OPMDs). This retrospective study includes 70 patients who underwent biopsy or surgical resection and were definitively diagnosed ...
Ryo Takasaki, Fumihiko Uchida, Shohei Takaoka, Ryota Ishii, Satoshi Fukuzawa, Eiji Warabi, Naomi Ishibashi-Kanno, Kenji Yamagata, Hiroki Bukawa, Toru Yanagawa   +9 more
doaj   +1 more source

Assessment of Ki67 in Breast Cancer: Updated Recommendations From the International Ki67 in Breast Cancer Working Group [PDF]

JNCI: Journal of the National Cancer Institute, 2020
AbstractKi67 immunohistochemistry (IHC), commonly used as a proliferation marker in breast cancer, has limited value for treatment decisions due to questionable analytical validity. The International Ki67 in Breast Cancer Working Group (IKWG) consensus meeting, held in October 2019, assessed the current evidence for Ki67 IHC analytical validity and ...
Torsten O Nielsen, Samuel C. Y Leung, David L Rimm, Andrew Dodson, Balazs Acs, Sunil Badve, Carsten Denkert, Matthew J Ellis, Susan Fineberg, Margaret Flowers, Hans H Kreipe, Anne-Vibeke Laenkholm, Hongchao Pan, Frédérique M Penault-Llorca, Mei-Yin Polley, Roberto Salgado, Ian E Smith, Tomoharu Sugie, John M. S Bartlett, Lisa M McShane, Mitch Dowsett, Daniel F Hayes   +21 more
openaire   +5 more sources

An Ethanolic Extract of Cucurbita pepo L. Seeds Modifies Neuroendocrine Disruption in Chronic Stressed Rats and Adrenal Expression of Inflammatory Markers and HSP70

Frontiers in Pharmacology, 2021
Background: Pumpkins (Cucurbita pepo L.) were described to have antioxidant, anti-inflammatory, anti-fatigue, and antidepressant-like effect. The adrenal gland is an important stress-responsive organ that maintains homeostasis during stress.Objectives ...
Hailah M. Almohaimeed, Shereen Hamed, Hanan S. Seleem, Hanan S. Seleem, Ashwaq H. Batawi, Zuhair M. Mohammedsaleh, Maha Jameal Balgoon, Soad S. Ali, Soad S. Ali, Soad Al Jaouni, Soad Al Jaouni, Nasra Ayuob   +11 more
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Plasmablastic lymphoma in immunocompetent and in immunocompromised patients: Experience at a regional cancer centre in India

South Asian Journal of Cancer, 2017
Introduction: Plasmablastic lymphoma (PBL) is a rare lymphoma associated with immunosuppression. It is strongly associated with immunosuppression (human immunodeficiency virus [HIV]) and often occurs within the oral cavity.
A H Rudresha, K C Lakshmaiah, Ankit Agarwal, K Govind Babu, D Loknatha, Linu Abraham Jacob, Suresh Babu, K N Lokesh, L K Rajeev   +8 more
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Sequential proliferative lesions in the cirrhotic liver of rats: a histopathological and immunohistochemical study [PDF]

Kafrelsheikh Veterinary Medical Journal, 2021
Background/aim: Liver cirrhosis is a common health problem that is mostly at the late stage associated with hepatic carcinogenesis. This study aimed to clarify the sequentialproliferative lesions in the cirrhotic liver induced chemically by thioacetamide
Marwa Darweish, Mahmoud GabAllh, AbdEl-baset El-Mashad, Shawky Moustafa, Aziza Amin   +4 more
doaj   +1 more source

Assessment of Ki67 in Breast Cancer: Recommendations from the International Ki67 in Breast Cancer Working Group [PDF]

JNCI Journal of the National Cancer Institute, 2011
Uncontrolled proliferation is a hallmark of cancer. In breast cancer, immunohistochemical assessment of the proportion of cells staining for the nuclear antigen Ki67 has become the most widely used method for comparing proliferation between tumor samples.
M. Dowsett, T. O. Nielsen, R. A'hern, J. Bartlett, R. C. Coombes, J. Cuzick, M. Ellis, N. L. Henry, J. C. Hugh, T. Lively, L. McShane, S. Paik, F. Penault Llorca, L. Prudkin, M. Regan, J. Salter, C. Sotiriou, I. E. Smith, G. Viale, J. A. Zujewski, D. F. Hayes   +20 more
openaire   +4 more sources

Systemic and Intra-Nodal Activation of NK Cells After Rituximab Monotherapy for Follicular Lymphoma

Frontiers in Immunology, 2019
Monotherapy with the anti-CD20 monoclonal antibody rituximab can induce complete responses (CR) in patients with follicular lymphoma (FL). Resting FcRγIII+ (CD16+) natural killer (NK) cells respond strongly to rituximab-coated target cells in vitro. Yet,
Monika Enqvist, Benedikt Jacobs, Benedikt Jacobs, Benedikt Jacobs, Henna R. Junlén, Henna R. Junlén, Marie Schaffer, Christopher M. Melén, Christopher M. Melén, Danielle Friberg, Björn Engelbrekt Wahlin, Björn Engelbrekt Wahlin, Karl-Johan Malmberg, Karl-Johan Malmberg, Karl-Johan Malmberg, Karl-Johan Malmberg, Karl-Johan Malmberg   +16 more
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The Role of Endoscopic Ultrasound-Guided Ki67 in the Management of Non-Functioning Pancreatic Neuroendocrine Tumors [PDF]

Clinical Endoscopy, 2020
Background/Aims The management of small, incidentally discovered nonfunctioning pancreatic neuroendocrine tumors (NF-PNETs) has been a matter of debate.
YongYan Cui, Lauren G. Khanna, Anjali Saqi, John P. Crapanzano, James M. Mitchell, Amrita Sethi, Tamas A. Gonda, Michael D. Kluger, Beth A. Schrope, John Allendorf, John A. Chabot, John M. Poneros   +11 more
doaj   +1 more source

Assessment of Inflammatory Domain on the Proliferative Activity of Odontogenic Keratocyst in Comparison with Dentigerous Cyst and Perapical Cyst

Journal of Orofacial Sciences, 2021
Introduction: Ki67 is a proven marker in assessing the aggressiveness of various neoplasms expressed in proliferating cells. The recognized role of p53 in a stress-induced cell represents gene mutation or disturbance of growth regulation.
Reshma Amin, Ramya Shenoy
doaj   +1 more source