Results 11 to 20 of about 146,439 (308)

Low correlation between Ki67 assessed by qRT-PCR in Oncotype Dx score and Ki67 assessed by Immunohistochemistry [PDF]

Scientific Reports, 2022
International audienceAbstract Breast cancers expressing high levels of Ki67 are associated with poor outcomes. Oncotype DX test was designed for ER+/HER2− early-stage breast cancers to help adjuvant chemotherapy decision by providing a Recurrent Score ...
Dobi, Erion, Mansi, Laura, Prétet, Jean-Luc, Selmani, Zohair, Viot, Julien, Feugeas, Jean-Paul, Curtit, Elsa, Meynard, Guillaume, Meneveau, Nathalie, Chaigneau, Loic, Molimard, Chloé, Bazan, Fernando, Borg, Christophe, Pivot, Xavier, Paillard, Marie-Justine, Algros, Marie-Paule, Overs, Alexis, Alexis Overs, Christophe Borg, Laura Mansi, Elsa Curtit, Erion Dobi, Zohair Selmani, Xavier Pivot, Nathalie Meneveau, Jean-Luc Prétet, Marie-Justine Paillard, Loic Chaigneau, Marie-Paule Algros, Julien Viot, Fernando Bazan, Jean-Paul Feugeas, Guillaume Meynard, Chloé Molimard   +33 more
core   +6 more sources

Meningiomas: Correlation of Ki67 with histological grade

Neurology India, 2011
Background : Meningiomas are slow-growing tumors. Grading of meningiomas based on histological features has certain limitations in predicting the exact biological behavior, necessitating ancillary techniques. Objective : To study the Ki67 labeling index
Purohit, A.K., Panigrahi, Manas Kumar, Uppin, Shantveer G., Saradhi, Vijay, Babu, Sashidhar, Challa, Sundaram, Uppin, Megha S., Sahu, B.P., Bhattacharjee, Suchanda   +8 more
core   +3 more sources

An International Ki67 Reproducibility Study [PDF]

JNCI: Journal of the National Cancer Institute, 2013
In breast cancer, immunohistochemical assessment of proliferation using the marker Ki67 has potential use in both research and clinical management. However, lack of consistency across laboratories has limited Ki67's value. A working group was assembled to devise a strategy to harmonize Ki67 analysis and increase scoring concordance.
Polley M. -Y. C., Leung S. C. Y., McShane L. M., Gao D., Hugh J. C., Mastropasqua M. G., Viale G., Zabaglo L. A., Penault-Llorca F., Bartlett J. M. S., Gown A. M., Symmans W. F., Piper T., Mehl E., Enos R. A., Hayes D. F., Dowsett M., Nielsen T. O.   +17 more
openaire   +4 more sources

p62 Is a Potential Biomarker for Risk of Malignant Transformation of Oral Potentially Malignant Disorders (OPMDs)

Current Issues in Molecular Biology, 2023
To determine the intracellular behavior of p62, a marker of selective autophagy, in oral potentially malignant disorders (OPMDs). This retrospective study includes 70 patients who underwent biopsy or surgical resection and were definitively diagnosed ...
Ryo Takasaki, Fumihiko Uchida, Shohei Takaoka, Ryota Ishii, Satoshi Fukuzawa, Eiji Warabi, Naomi Ishibashi-Kanno, Kenji Yamagata, Hiroki Bukawa, Toru Yanagawa   +9 more
doaj   +1 more source

Assessment of Ki67 in Breast Cancer: Updated Recommendations From the International Ki67 in Breast Cancer Working Group [PDF]

JNCI: Journal of the National Cancer Institute, 2020
AbstractKi67 immunohistochemistry (IHC), commonly used as a proliferation marker in breast cancer, has limited value for treatment decisions due to questionable analytical validity. The International Ki67 in Breast Cancer Working Group (IKWG) consensus meeting, held in October 2019, assessed the current evidence for Ki67 IHC analytical validity and ...
Torsten O Nielsen, Samuel C. Y Leung, David L Rimm, Andrew Dodson, Balazs Acs, Sunil Badve, Carsten Denkert, Matthew J Ellis, Susan Fineberg, Margaret Flowers, Hans H Kreipe, Anne-Vibeke Laenkholm, Hongchao Pan, Frédérique M Penault-Llorca, Mei-Yin Polley, Roberto Salgado, Ian E Smith, Tomoharu Sugie, John M. S Bartlett, Lisa M McShane, Mitch Dowsett, Daniel F Hayes   +21 more
openaire   +5 more sources

Stromal tissue segmentation in Ki67 histology images based on cytokeratin-19 stain translation [PDF]

, 2023
Purpose: The diagnosis and prognosis of breast cancer relies on histopathology image analysis. In this context, proliferation markers, especially Ki67, are increasingly important.
Philippe Salembier, Marqués Acosta, Fernando, David Anglada-Rotger, Salembier Clairon, Philippe Jean, Ferran Marqués, Pardàs Feliu, Montse, Anglada Rotger, David, Maria Espina, Montse Pardàs, Espina Boronat, Maria   +9 more
core   +1 more source

An Ethanolic Extract of Cucurbita pepo L. Seeds Modifies Neuroendocrine Disruption in Chronic Stressed Rats and Adrenal Expression of Inflammatory Markers and HSP70

Frontiers in Pharmacology, 2021
Background: Pumpkins (Cucurbita pepo L.) were described to have antioxidant, anti-inflammatory, anti-fatigue, and antidepressant-like effect. The adrenal gland is an important stress-responsive organ that maintains homeostasis during stress.Objectives ...
Hailah M. Almohaimeed, Shereen Hamed, Hanan S. Seleem, Hanan S. Seleem, Ashwaq H. Batawi, Zuhair M. Mohammedsaleh, Maha Jameal Balgoon, Soad S. Ali, Soad S. Ali, Soad Al Jaouni, Soad Al Jaouni, Nasra Ayuob   +11 more
doaj   +1 more source

Sequential proliferative lesions in the cirrhotic liver of rats: a histopathological and immunohistochemical study [PDF]

Kafrelsheikh Veterinary Medical Journal, 2021
Background/aim: Liver cirrhosis is a common health problem that is mostly at the late stage associated with hepatic carcinogenesis. This study aimed to clarify the sequentialproliferative lesions in the cirrhotic liver induced chemically by thioacetamide
Marwa Darweish, Mahmoud GabAllh, AbdEl-baset El-Mashad, Shawky Moustafa, Aziza Amin   +4 more
doaj   +1 more source

Systemic and Intra-Nodal Activation of NK Cells After Rituximab Monotherapy for Follicular Lymphoma

Frontiers in Immunology, 2019
Monotherapy with the anti-CD20 monoclonal antibody rituximab can induce complete responses (CR) in patients with follicular lymphoma (FL). Resting FcRγIII+ (CD16+) natural killer (NK) cells respond strongly to rituximab-coated target cells in vitro. Yet,
Monika Enqvist, Benedikt Jacobs, Benedikt Jacobs, Benedikt Jacobs, Henna R. Junlén, Henna R. Junlén, Marie Schaffer, Christopher M. Melén, Christopher M. Melén, Danielle Friberg, Björn Engelbrekt Wahlin, Björn Engelbrekt Wahlin, Karl-Johan Malmberg, Karl-Johan Malmberg, Karl-Johan Malmberg, Karl-Johan Malmberg, Karl-Johan Malmberg   +16 more
doaj   +1 more source

Assessment of Inflammatory Domain on the Proliferative Activity of Odontogenic Keratocyst in Comparison with Dentigerous Cyst and Perapical Cyst

Journal of Orofacial Sciences, 2021
Introduction: Ki67 is a proven marker in assessing the aggressiveness of various neoplasms expressed in proliferating cells. The recognized role of p53 in a stress-induced cell represents gene mutation or disturbance of growth regulation.
Reshma Amin, Ramya Shenoy
doaj   +1 more source