Results 11 to 20 of about 177,505 (309)

RET mutated C-cells proliferate more rapidly than non-mutated neoplastic cells

Endocrine Connections, 2021
A statistically significant higher prevalence of the RET p.Met918Thr somatic mutation, identified by direct sequencing, was previously reported in MTC > 2 cm than in smaller tumors. Aim of this study was to correlate the full RET and RAS mutation profile,
Cristina Romei, Teresa Ramone, Chiara Mulè, Alessandro Prete, Virginia Cappagli, Loredana Lorusso, Liborio Torregrossa, Fulvio Basolo, Raffaele Ciampi, Rossella Elisei   +9 more
doaj   +1 more source

p62 Is a Potential Biomarker for Risk of Malignant Transformation of Oral Potentially Malignant Disorders (OPMDs)

Current Issues in Molecular Biology, 2023
To determine the intracellular behavior of p62, a marker of selective autophagy, in oral potentially malignant disorders (OPMDs). This retrospective study includes 70 patients who underwent biopsy or surgical resection and were definitively diagnosed ...
Ryo Takasaki, Fumihiko Uchida, Shohei Takaoka, Ryota Ishii, Satoshi Fukuzawa, Eiji Warabi, Naomi Ishibashi-Kanno, Kenji Yamagata, Hiroki Bukawa, Toru Yanagawa   +9 more
doaj   +1 more source

Assessment of Ki67 in Breast Cancer: Updated Recommendations From the International Ki67 in Breast Cancer Working Group [PDF]

JNCI: Journal of the National Cancer Institute, 2020
AbstractKi67 immunohistochemistry (IHC), commonly used as a proliferation marker in breast cancer, has limited value for treatment decisions due to questionable analytical validity. The International Ki67 in Breast Cancer Working Group (IKWG) consensus meeting, held in October 2019, assessed the current evidence for Ki67 IHC analytical validity and ...
Torsten O Nielsen, Samuel C. Y Leung, David L Rimm, Andrew Dodson, Balazs Acs, Sunil Badve, Carsten Denkert, Matthew J Ellis, Susan Fineberg, Margaret Flowers, Hans H Kreipe, Anne-Vibeke Laenkholm, Hongchao Pan, Frédérique M Penault-Llorca, Mei-Yin Polley, Roberto Salgado, Ian E Smith, Tomoharu Sugie, John M. S Bartlett, Lisa M McShane, Mitch Dowsett, Daniel F Hayes   +21 more
openaire   +5 more sources

Analysis of the prognostic survival of Ki67, CEA, CA199 and relevant clinical pathological features in metastatic colorectal cancer

结直肠肛门外科, 2023
[Objectives] To analyze the relationship between Ki67, CEA, CA199, and relevant clinical pathological features and the prognostic survival of metastatic colorectal cancer (mCRC).
Huang Jian, Fan Yufang, Chen Yuemiao, Huang Lifeng, Cai Xiaoping   +4 more
doaj   +1 more source

Synaptophysin-Ki67 double stain: a novel technique that improves interobserver agreement in the grading of well-differentiated gastrointestinal neuroendocrine tumors. [PDF]

, 2017
A common problem in the assessment of Ki67 proliferative index in well-differentiated gastrointestinal neuroendocrine tumors is distinguishing tumor from non-tumor.
Beckett, Laurel, Gandour-Edwards, Regina, Gui, Dorina, Li, Yueju, Matsukuma, Karen, Olson, Kristin A   +5 more
core   +1 more source

HPV infection and immunochemical detection of cell-cycle markers in verrucous carcinoma of the penis [PDF]

, 2009
Penile verrucous carcinoma is a rare disease and little is known of its aetiology or pathogenesis. In this study we examined cell-cycle proteins expression and correlation with human papillomavirus infection in a series of 15 pure penile verrucous ...
A Ouban, AL Cubilla, AL Cubilla, AL Cubilla, AL Cubilla, AL Cubilla, AL Seixas, AS Masih, AS Narayana, B Kleter, C Dianzani, C Missero, Catherine Corbishley, CB Bunker, CL Haycox, Daniel M Berney, David M Prowse, DE Johnson, DM Prowse, E Ferreux, EF Velazquez, Elena Ktori, Elzbieta Stankiewicz, FT Kraus, GD Higgins, IB Roninson, Jack Cuzick, JC Noel, JR Nevins, KH Cuesta, KW Chan, KY Lam, KY Lam, L Gregoire, Laurence Ambroisine, LC Cubilla, LH Sobin, LL Villa, LV Ackerman, M Gualco, M Senba, M Serrano, M Wong, MA Rubin, MR Cupp, MT Kiyabu, Nicholas Watkin, PA Adegboyega, PA Hall, PH McKee, S Pilotti, Sakunthala C Kudahetti, SL Harris, T Sano, TH Cheung, VA Tron, VA Varma, Xiaoxi Zhang, Y Koyamatsu   +58 more
core   +1 more source

Plasmablastic lymphoma in immunocompetent and in immunocompromised patients: Experience at a regional cancer centre in India

South Asian Journal of Cancer, 2017
Introduction: Plasmablastic lymphoma (PBL) is a rare lymphoma associated with immunosuppression. It is strongly associated with immunosuppression (human immunodeficiency virus [HIV]) and often occurs within the oral cavity.
A H Rudresha, K C Lakshmaiah, Ankit Agarwal, K Govind Babu, D Loknatha, Linu Abraham Jacob, Suresh Babu, K N Lokesh, L K Rajeev   +8 more
doaj   +1 more source

Assessment of Ki67 in Breast Cancer: Recommendations from the International Ki67 in Breast Cancer Working Group [PDF]

JNCI Journal of the National Cancer Institute, 2011
Uncontrolled proliferation is a hallmark of cancer. In breast cancer, immunohistochemical assessment of the proportion of cells staining for the nuclear antigen Ki67 has become the most widely used method for comparing proliferation between tumor samples.
M. Dowsett, T. O. Nielsen, R. A'hern, J. Bartlett, R. C. Coombes, J. Cuzick, M. Ellis, N. L. Henry, J. C. Hugh, T. Lively, L. McShane, S. Paik, F. Penault Llorca, L. Prudkin, M. Regan, J. Salter, C. Sotiriou, I. E. Smith, G. Viale, J. A. Zujewski, D. F. Hayes   +20 more
openaire   +4 more sources

Systemic and Intra-Nodal Activation of NK Cells After Rituximab Monotherapy for Follicular Lymphoma

Frontiers in Immunology, 2019
Monotherapy with the anti-CD20 monoclonal antibody rituximab can induce complete responses (CR) in patients with follicular lymphoma (FL). Resting FcRγIII+ (CD16+) natural killer (NK) cells respond strongly to rituximab-coated target cells in vitro. Yet,
Monika Enqvist, Benedikt Jacobs, Benedikt Jacobs, Benedikt Jacobs, Henna R. Junlén, Henna R. Junlén, Marie Schaffer, Christopher M. Melén, Christopher M. Melén, Danielle Friberg, Björn Engelbrekt Wahlin, Björn Engelbrekt Wahlin, Karl-Johan Malmberg, Karl-Johan Malmberg, Karl-Johan Malmberg, Karl-Johan Malmberg, Karl-Johan Malmberg   +16 more
doaj   +1 more source

Effects of propolis on histopathological and immunohistochemical alterations in testes of thyroidectomized rat. [PDF]

Journal of Bioscience and Applied Research, 2016
The thyroid hormones, triiodothyronine (T3) and its prohormone, thyroxine, are secreted by the thyroid gland which are responsible for the regulation of metabolism in all body tissues.
Ezar Hafez
doaj   +1 more source