Results 51 to 60 of about 239,474 (338)

Do YOU know the Ki-67 index of your breast cancer patients? Knowledge of your institution’s Ki-67 index distribution and its robustness is essential for decision-making in early breast cancer

Breast, 2020
Objectives: The proliferative activity of the Ki-67 index is important in decision-making of adjuvant treatments in early breast cancer. Its reliability can be reduced by inter-observer variability.
Angela Fischer Maranta, Simon Broder, Constanze Fritzsche, Michael Knauer, Beat Thürlimann, Wolfram Jochum, Thomas Ruhstaller   +6 more
doaj   +1 more source

The role of the two splice variants and extranuclear pathway on Ki-67 regulation in non-cancer and cancer cells [PDF]

, 2017
Ki-67 is a nuclear protein that has been used in cancer diagnostic because of its specific cell-cycle dependent expression profile. After quantifying and characterising the expression level of Ki-67, as a function of the cell cycle, we found out that the
Battaglia, G, Chierico, L, Guan, L, Joseph, AS, Lewis, A, Rizzello, L   +5 more
core   +1 more source

MKI67 (marker of proliferation Ki-67) [PDF]

Atlas of Genetics and Cytogenetics in Oncology and Haematology, 2015
Review on MKI67 (marker of proliferation Ki-67), with data on DNA, on the protein encoded, and where the gene is implicated.
Ntzeros, K, Stanier, P, Mazis, D, Kritikos, N, Rozis, M, Anesidis, E, Antoniou, C, Stamatakos, M   +7 more
openaire   +2 more sources

A subset of MMR‐proficient colon cancers responds to neoadjuvant immunotherapy

Molecular Oncology, EarlyView.
Tan et al. reveal that a distinct subset of early‐stage pMMR colon cancers can respond to neoadjuvant immunotherapy. In the NICHE‐2 trial, responders (26%) were characterized by chromosomal instability, TP53 mutations, and proliferative cell‐cycle programs, whereas nonresponders showed metabolic and stromal reprogramming with TGF‐β‐driven ...
Eleonora Piumatti, Giovanni Germano, Pietro Paolo Vitiello, Alberto Bardelli   +3 more
wiley   +1 more source

Prognostic Value of Ki-67 Index in Patients With Endometrial Stromal Sarcoma

Frontiers in Medicine, 2022
ObjectiveThe Ki-67 index is used to evaluate cell proliferation activity, which is related to tumor progression, metastasis, and prognosis. We aimed to explore the prognostic value of Ki-67 index in endometrial stromal sarcoma and to explore the optimal ...
Yu Meng, Quan Quan, Fenfen Zhang, Yao Liu, Siling Ren, Xiaoling Mu   +5 more
doaj   +1 more source

Evaluation of the Ki-67 and MCM3 Expression in Cytologic Smear of Oral Squamous Cell Carcinoma [PDF]

, 2017
Statement of the Problem: Squamous cell carcinoma (SCC) is the most frequent oral cancer whose 5-year survival rate is 80% for early-detected lesions and nearly 30-50% for advanced lesions.
Andisheh-Tadbir, Azadeh., Ashraf, Mohammad Javad., Ebrahimi, Rahele., Khademi, Bijan., Rezazadeh, Fahimeh.   +4 more
core   +1 more source

Frequency of Chlamydia trachomatis infection in cervical intraepithelial lesions and the status of cytological p16/Ki-67 dual-staining [PDF]

, 2017
Background: Chlamydia trachomatis (Ct) is not a disease subject to mandatory reporting in Brazil, and the prevalence rate of this genital infection varies according to the region in which studies are conducted, as well as by the detection technique ...
A Longatto Filho, A. Longatto-Filho, AB Moscicki, AL Abreu de, C Bergeron, C Santos, C. M. Roteli-Martins, D Motta, D. Stauffert, E. C. Baracat, G. G. Ribeiro, I. M. Linhares, J Ordi, J Silva, JS Smith, K Nanda, K Owusu-Edusei Jr, KE Jensen, LB Fernandes, M Pantoja, M Safaeian, M. A. Zonta, M. F. Silveira, M. Tacla, MI Rosa, ML Shew, N Low, N Wentzensen, PA Magalhaes, R. Robial, RC Piazzetta, SM Redmond, T Luostarinen   +32 more
core   +3 more sources

Overview of molecular signatures of senescence and associated resources: pros and cons

FEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas, Sylvia Vagena, Pavlos Pantelis, Giorgos Theocharous, Russel Petty, Konstantinos Evangelou, Vassilis G. Gorgoulis   +6 more
wiley   +1 more source

Prognostic Importance of Ki-67 in Breast Cancer and Its Relationship with Other Prognostic Factors

European Journal of Breast Health, 2019
Objective:The clinical feature of breast cancer is very heterogeneous because of the variable prognostic factors impact its behaviour. The aim of study is to find the prognostic importance of Ki-67 and to analyse the correlation between Ki-67 index and ...
Gül Kanyılmaz, Berrin Benli Yavuz, Meryem Aktan, Mustafa Karaağaç, Mehmet Uyar, Sıddıka Fındık   +5 more
doaj   +1 more source

Prediction of the Ki-67 marker index in hepatocellular carcinoma based on Dynamic Contrast-Enhanced Ultrasonography with Sonazoid

Insights into Imaging, 2022
Background Ki-67 is widely used as a proliferative and prognostic factor in HCC. This study aimed to analyze the relationship between dynamic contrast-enhanced ultrasonography (DCE-US) parameters and Ki-67 expression.
Zhe Huang, PingPing Zhou, ShanShan Li, Kaiyan Li   +3 more
doaj   +1 more source