Results 61 to 70 of about 239,474 (338)

Biological subtyping of early breast cancer : a study comparing RT-qPCR with immunohistochemistry [PDF]

, 2016
The biological subtype of breast cancer influences the selection of systemic therapy. Distinction between luminal A and B cancers depends on consistent assessment of Ki-67, but substantial intra-observer and inter-observer variability exists when ...
Auvinen, Paivi, Eidt, Sebastian, Heikkila, Paivi, Isola, Jorma, Joensuu, Heikki, Jyrkkio, Sirkku, Kellokumpu-Lehtinen, Pirkko-Liisa, Laible, Mark, Lakis, Sotiris, Sahin, Ugur, Schlombs, Kornelia, Sihto, Harri, Turpeenniemi-Hujanen, Taina, Weber, Stefan, Wirtz, Ralph M.   +14 more
core   +2 more sources

Understanding bio‐based polymers: A study of origins, properties, biodegradation and their impact on health and the environment

FEBS Open Bio, EarlyView.
This review provides an overview of bio‐based polymer sources, their unique functional properties and their environmental impact, and addresses their role as sustainable alternatives. It discusses end‐of‐life options, including composting and anaerobic digestion for renewable energy.
Sabina Kolbl Repinc, Blaž Stres, Mirica Karlovits, Igor Karlovits, Petra Jerič, Ondrej Panák, Anja Verbič, Blaž Likozar, Uroš Novak   +8 more
wiley   +1 more source

Ki-67 as a prognostic marker according to breast cancer molecular subtype

Cancer Biology & Medicine, 2016
Objective: Ki-67 plays an important function in cell division, but its exact role is still unknown. Moreover, few works regarding its overall function were published.
Nahed A. Soliman, Shaimaa M. Yussif
doaj   +1 more source

Plasma Proteomic Signatures for Alzheimer's Disease: Comparable Accuracy to ATN Biomarkers and Cross‐Platform Validation

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background There is growing recognition of the potential of plasma proteomics for Alzheimer's Disease (AD) risk assessment and disease characterization. However, differences between proteomics platforms introduce uncertainties regarding cross‐platform applicability.
Manyue Hu, Oliver Robinson, Christina M. Lill, Anna Matton, Raquel Puerta, Pilar Sanz, Merce Boada, Agustín Ruiz, Lefkos Middleton, for the Alzheimer's Disease Neuroimaging Initiative   +9 more
wiley   +1 more source

Real‐World Performance of CSF Kappa Free Light Chains in the 2024 McDonald Criteria

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Kappa free light chains (KFLCs) in the cerebrospinal fluid (CSF) have a similar performance to CSF‐restricted oligoclonal bands (OCB) for multiple sclerosis (MS) diagnosis. To help with implementation, we set out to resolve several remaining uncertainties: (1) performance in a real‐world cohort and the 2024 McDonald criteria; (2 ...
Maya M. Leibowitz, Ryan Cooper, Stefania Kaninia, Kathryn I. Challis, Will Greenway, Maria Bonello, Mahmoud Elbahnasawi, Deborah T. Shode, Dominika Gajdasik, Victor Iliev, Alison M. E. Whitelegg, Ian Galea   +11 more
wiley   +1 more source

Elevated Ki-67 (MIB-1) expression as an independent predictor for unfavorable pathologic outcomes and biochemical recurrence after radical prostatectomy in patients with localized prostate cancer: A propensity score matched study.

PLoS ONE, 2019
BACKGROUND:Ki-67 is known to be useful in estimating the fraction of proliferation tumor cells in various malignancies. We tried to investigate clinical association of Ki-67 (MIB-1) expression with the oncological outcomes in patients with localized ...
Seok-Soo Byun, Minseung Lee, Sung Kyu Hong, Hakmin Lee   +3 more
doaj   +1 more source

Ki-67 and CD100 immunohistochemical expression is associated with local recurrence and poor prognosis in soft tissue sarcomas, respectively [PDF]

, 2013
Soft tissue sarcomas (STSs) are a heterogeneous group of mesenchymal tumors of >50 subtypes. However, STSs represent
ADHEMAR LONGATTO-FILHO, ALLINI MAFRA DA COSTA, Behar, Brown, Choong, Ch’ng, Ch’ng, CLEYTON ZANARDO DE OLIVEIRA, Conrotto, Conrotto, EMÍLIO CARLOS CURCELLI, Endl, Fletcher, FLÁVIA COLTRI EGUCHI, Gerdes, Goodman, GUILHERME GOMES RIBEIRO, Hall, Heslin, Hoos, Huutanen, Jensen, Jones, Kato, Kitsukawa, Kolodkin, Kumanogoh, Luo, MARCELO CAMPOS, MARCOS CEITA NUNES, Mizui, Ottaiano, Popiolek, Roche, Rody, SANDRA REGINA MORINI DA SILVA, Sekido, SILVANA GISELE PEGORIN DE CAMPOS, Taylor, Tessier-Lavigne, Ueda, VALTER PENNA   +41 more
core   +1 more source

A 73‐Year‐Old Man With Several Years of Difficulty Climbing Stairs and Frequent Tripping

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT A 73‐year‐old man presented with progressive weakness and atrophy predominantly affecting the distal finger flexors and quadriceps muscles. Electrophysiological studies demonstrated mixed myogenic and neurogenic features. Muscle MRI showed inflammatory changes, and muscle biopsy revealed granulomatous myositis with histologic features ...
Mehmet Can Sari, Arens Taga, Sonya Ulrike Steele, Ahmet Hoke   +3 more
wiley   +1 more source

Expression of proliferative marker Ki-67 in epithelial dysplasia and squamous cell carcinoma of oral cavity [PDF]

Journal of Krishna Institute of Medical Sciences University, 2023
Background: The proliferative index helps to evaluate the growth rate and aggressiveness of the malignant tumor. Ki-67 is one of the proliferating markers that help to predict the patient's survival in Oral Epithelial Dysplasia (OED) and Oral Squamous ...
Payal Doctor, Surekha U Arakeri , Venkatesh Patil   +2 more
doaj  

Lymph node metastases displaying lower Ki-67 immunostaining activity than the primary breast cancer [PDF]

, 2006
The aim of the study was to verify by Ki-67 immunostaining if any difference exists in the cell proliferating fraction between primary breast tumors (PTs) and matching positive axillary lymph nodes (ALNs).
ARAGONA F., CABIBI, Daniela, CALASCIBETTA, Anna, CAMPIONE M, MARTORANA, Anna, MUSTACCHIO V, SANGUEDOLCE, Rosario, TRIPODO, Claudio   +7 more
core