The cell proliferation antigen Ki-67 organises heterochromatin
eLife, 2016 Antigen Ki-67 is a nuclear protein expressed in proliferating mammalian cells. It is widely used in cancer histopathology but its functions remain unclear. Here, we show that Ki-67 controls heterochromatin organisation.
Michal Sobecki +20 more
doaj +7 more sources
Ki-67 Antigen Overexpression Is Associated with the Metaplasia-Adenocarcinoma Sequence in Barrett's Esophagus [PDF]
Gastroenterology Research and Practice, 2012 Introduction. The objective of this study was to evaluate Ki-67 antigen expression in patients with Barrett’s esophagus and esophageal adenocarcinoma and to assess its correlation with the metaplasia-esophageal adenocarcinoma progression. Methods.
Bernardo Silveira Volkweis +5 more
doaj +2 more sources
Ki-67 Antigen; A Valuable Prognostic Biomarker for Chronic Lymphocytic Leukemia [PDF]
مجله دانشکده پزشکی اصفهان, 2022 Background: Chronic lymphocytic leukemia (CLL) is one of the most common blood malignancies. The chief cells involved in this malignancy are in the G0 phase of cell division and have no proliferative activity; however, what determines the severity and ...
Valiollah Mehrzad, Samaneh Madadi
doaj +2 more sources
Vascular Endothelial Growth Factor and Ki-67 Antigen Expression in Relation to Age and Gender in Oral Squamous Cell Carcinoma [PDF]
Journal of Dental Research, Dental Clinics, Dental Prospects, 2012 Background and aims. Vascular endothelial growth factor (VEGF) and Ki-67 antigen are contributing factors in this process cell proliferation and new blood vessels formation in tumor progression.
Noushin Jalayer Naderi +4 more
doaj +2 more sources
Obtaining Specific Hybridomas for Ki-67 Protein Immunodetection
Indonesian Biomedical Journal, 2021 BACKGROUND: Active proliferation is specific property of a tumor cells. However, the cost of the analysis is high due to commercial anti-Ki-67 mAbs used as the main immunoreagent for reliable identification of proliferating cells.
Aigerim Turgimbayeva +4 more
doaj +1 more source
Value of the proliferative and hormonal markers in estimation of biological behaviour of meningioma [PDF]
Archive of Oncology, 2002 (Conclusion) Although the proliferative markers and hormonal (progesterone) receptor status of meningiomas seem to provide useful, convenient, and predictive criterions for the subsequent evolution of the tumor, they should be used only in combination ...
Skender-Gazibara Milica +3 more
doaj +1 more source
Acta Cirúrgica Brasileira, 2023 Purpose: The effects of hesperidin application on the wound caused by esophageal burns were investigated in this study. Methods: Wistar albino rats were divided into three groups: Control group: only 1 mL of 0.09% NaCl was administered i.p. for 28 days;
Cemalettin Durgun +2 more
doaj +1 more source
Combination of Binary System with Ki67 Immunohistochemical Staining: a Reliable Grading Method for Oral Epithelial Dysplasia [PDF]
Journal of Dentistry, 2022 Statement of the Problem: Oral epithelial dysplasia (OED) is a common potentially malignant lesion of oral cavity that should be managed to prevent likely malignant transformation.
Negar Akafzadeh +5 more
doaj +1 more source
Developmental expression of Ki‐67 antigen and proliferating cell nuclear antigen in macaque placentas [PDF]
Developmental Dynamics, 1994 AbstractPlacental growth is largely determined by the proliferation of cytotrophoblast cells. However, the distribution of cytotrophoblast cells engaged in the cell cycle during placental development is poorly understood. Recently, antibodies have been developed that identify two proteins directly involved with DNA synthesis: Ki‐67 protein and ...
T N, Blankenship, B F, King
openaire +2 more sources
Is Ki-67, keratin 16, involucrin, and filaggrin immunostaining sufficient to diagnose inflammatory linear verrucous epidermal nevus? A report of eight cases and a comparison with psoriasis vulgaris [PDF]
Anais Brasileiros de Dermatologia, 2017 : Inflammatory linear verrucous epidermal nevus and linear psoriasis are sometimes hard to differentiate clinically and pathologically. Although immunohistochemical expression of keratin 10 (K10), K16, Ki-67, and involucrin may be useful for ...
Jing Peng +3 more
doaj +2 more sources