Results 31 to 40 of about 469,658 (145)

The temporal pattern and lifestyle associations of respiratory virus infection in a cohort study spanning the first two years of life

BMC Pediatrics, 2022
Background Respiratory virus infection is common in early childhood, and children may be symptomatic or symptom-free. Little is known regarding the association between symptomatic/asymptomatic infection and particular clinical factors such as ...
Elizabeth Powell, Edward Sumner, Alex G. Shaw, Ronan Calvez, Colin G. Fink, J. Simon Kroll   +5 more
doaj   +1 more source

Identification and Characterization of Novel Rat Polyomavirus 2 in a Colony of X-SCID Rats by P-PIT assay

mSphere, 2016
Polyomaviruses (PyVs) are known to infect a wide range of vertebrates and invertebrates and are associated with a broad spectrum of diseases, including cancers, particularly in immune-suppressed hosts. A novel polyomavirus, designated rat polyomavirus 2 (
Lora H. Rigatti, Tuna Toptan, Joseph T. Newsome, Patrick S. Moore, Yuan Chang   +4 more
doaj   +1 more source

BKV Agnoprotein Interacts with α-Soluble N-Ethylmaleimide-Sensitive Fusion Attachment Protein, and Negatively Influences Transport of VSVG-EGFP [PDF]

, 2011
Background: The human polyomavirus BK (BKV) infects humans worldwide and establishes a persistent infection in the kidney. The BK virus genome encodes three regulatory proteins, large and small tumor-antigen and the agnoprotein, as well as the capsid ...
Johannessen, M., Mona Johannessen, Walquist, Mari, Moens, Ugo, Walquist Mari, Spang Anne, Mari Walquist, Moens Ugo, Anne Spang, Gerits, N., Spang, Anne, Johannessen, Mona, Marte Dragset, Gerits Nancy, Johannessen Mona, Nancy Gerits, Ugo Moens, Dragset Marte, Walquist, M., Gerits, Nancy, Dragset, Marte Singsås, Dragset, M., Spang, A., Moens, U.   +23 more
core   +1 more source

WU Polyomavirus in Children with Acute Lower Respiratory Tract Infections, South Korea

Emerging Infectious Diseases, 2007
In South Korea, WU polyomavirus (WUPyV) was detected in 34 (7%) of 486 children with acute lower respiratory tract infections, 3 (4.2%) of 72 asymptomatic children, and as coinfection with other respiratory viruses in 23 (67.6%) children.
Tae Hee Han, Ju-Young Chung, Ja Wook Koo, Sang Woo Kim, Eung-Soo Hwang   +4 more
doaj   +1 more source

JC virus evolution and its association with human populations [PDF]

, 2006
The ubiquitous human polyomavirus JC (JCV) is a small double-stranded DNA virus that establishes a persistent infection, and it is often transmitted from parents to children.
Edward C. Holmes, Andrew Rambaut, Shackelton, Laura A., Rambaut, Andrew, Oliver G. Pybus, Laura A. Shackelton, Pybus, Oliver G., Holmes, Edward C.   +7 more
core   +1 more source

Role of Human Polyomaviruses in Respiratory Tract Disease in Young Children

Emerging Infectious Diseases, 2008
KI virus was detected in respiratory secretions of 8/367 (2.2%) symptomatic and 0/96 asymptomatic children (p = 0.215). WU virus was detected in 26/367 (7.1%) symptomatic and 6/96 (6.3%) asymptomatic children (p = 1.00).
Rachel L. Wattier, Marietta Vázquez, Carla Weibel, Eugene D. Shapiro, David Ferguson, Marie L. Landry, Jeffrey S. Kahn   +6 more
doaj   +1 more source

High‐Throughput Synthesis and Screening of a Cyanimide Library Identifies Selective Inhibitors of ISG15‐Specific Protease mUSP18

Angewandte Chemie, Volume 137, Issue 49, December 1, 2025.
Deubiquitinases (DUBs) and Ub‐like proteases are attractive but challenging drug targets. We developed a high‐throughput synthesis method and prepared a 7536‐member cyanimide DUB‐targeted compound library in 1536‐well plates, using Echo acoustic dispensing. Screening yielded a selective, 35 nM inhibitor of mUSP18, the main ISG15 protease.
Raymond Kooij, Vito Pol, Jin Gan, Bjorn R. van Doodewaerd, Aysegul Sapmaz, Marta Campos Alonso, Günter Fritz, Klaus‐Peter Knobeloch, Paul P. Geurink   +8 more
wiley   +2 more sources

The polyomaviruses WUPyV and KIPyV: a retrospective quantitative analysis in patients undergoing hematopoietic stem cell transplantation

Virology Journal, 2012
Background The polyomaviruses WUPyV and KIPyV have been detected in various sample types including feces indicating pathogenicity in the gastrointestinal (GI) system.
Motamedi Nasim, Mairhofer Helga, Nitschko Hans, Jäger Gundula, Koszinowski Ulrich H   +4 more
doaj   +1 more source

T‐Cell Remodeling in Renal Fibrosis: From Acute Injury to Chronic Kidney Disease

Advanced Science, Volume 13, Issue 58, 19 October 2026.
This Review presents renal fibrosis as a sequence of overlapping T‐cell programs, from chemokine‐guided recruitment and metabolic activation to maladaptive polarization, tertiary lymphoid structure formation, tissue residency, exhaustion, and senescence.
Qianhui Li, Junting Guan, Yifan Song, Hongxia Yang, Guangtao Li, Xiaodong Zhao, Jiaxin Liu, Bin Liu, Yang Tan, Honglan Zhou, Yang‐He Zhang, Yishu Wang   +11 more
wiley   +1 more source

Isolement et identification du polyomavirus agent de la néphrite hémorragique entérite de l'oie (N.H.E.O.) [PDF]

, 2002
L'agent de la Néphrite Hémorragique Entérite de l'Oison (NHEO) a été identifié. Sévissant de façon épizootique dans toutes les régions françaises productrices d'oie, son étiologie est resté jusqu'à maintenant inconnue.
Dubois, Luc
core