Results 31 to 40 of about 3,591 (186)

Detection of KI WU and Merkel cell polyomavirus in respiratory tract of cystic fibrosis patients [PDF]

Clinical Microbiology and Infection, 2015
In the last few years, many reports have confirmed the presence of WU, KI and Merkel cell (MC) polyomaviruses (PyV) in respiratory samples wordwide, but their pathogenic role in patients with underlying conditions such as cystic fibrosis is still debated.
IARIA, Marialuisa, CACCURI, Francesca, APOSTOLI, Paola, GIAGULLI, Cinzia, PELUCCHI, Francesca, Padoan, Rf, CARUSO, Arnaldo, FIORENTINI, Simona   +7 more
openaire   +3 more sources

Identification of a novel human polyomavirus in organs of the gastrointestinal tract [PDF]

, 2013
Peer reviewedPublisher ...
Calvignac-Spencer, Sebastien, Ehlers, Bernhard, Hofmann, Jorg, Korup, Sarah, Moens, Ugo, Rietscher, Janita, Sauer, Igor, Schmuck, Rosa, Trusch, Franziska, Voigt, Sebastian   +9 more
core   +4 more sources

Serologic Evidence of Frequent Human Infection with WU and KI Polyomaviruses

Emerging Infectious Diseases, 2009
WU polyomavirus (WUPyV) and KI polyomavirus (KIPyV) are novel human polyomaviruses. They were originally identified in human respiratory secretions, but the extent of human infection caused by these viruses has not been described to date.
Nang L. Nguyen, Binh-Minh Le, David Wang
doaj   +1 more source

The temporal pattern and lifestyle associations of respiratory virus infection in a cohort study spanning the first two years of life

BMC Pediatrics, 2022
Background Respiratory virus infection is common in early childhood, and children may be symptomatic or symptom-free. Little is known regarding the association between symptomatic/asymptomatic infection and particular clinical factors such as ...
Elizabeth Powell, Edward Sumner, Alex G. Shaw, Ronan Calvez, Colin G. Fink, J. Simon Kroll   +5 more
doaj   +1 more source

Broad Virus Detection and Variant Discovery in Fecal Samples of Hematopoietic Transplant Recipients Using Targeted Sequence Capture Metagenomics

Frontiers in Microbiology, 2020
Pediatric allogeneic hematopoietic stem cell transplantation (HSCT) patients often suffer from gastro-intestinal (GI) disease caused by viruses, Graft-versus-Host Disease (GVHD) or a combination of the two.
Suze A. Jansen, Suze A. Jansen, Wouter Nijhuis, Helen L. Leavis, Annelies Riezebos-Brilman, Caroline A. Lindemans, Caroline A. Lindemans, Rob Schuurman   +7 more
doaj   +1 more source

Identification and Characterization of Novel Rat Polyomavirus 2 in a Colony of X-SCID Rats by P-PIT assay

mSphere, 2016
Polyomaviruses (PyVs) are known to infect a wide range of vertebrates and invertebrates and are associated with a broad spectrum of diseases, including cancers, particularly in immune-suppressed hosts. A novel polyomavirus, designated rat polyomavirus 2 (
Lora H. Rigatti, Tuna Toptan, Joseph T. Newsome, Patrick S. Moore, Yuan Chang   +4 more
doaj   +1 more source

Detection and characterization of two chimpanzee polyomavirus genotypes from different subspecies [PDF]

, 2010
The complete nucleotide sequences of three chimpanzee polyomavirus genetic variants were determined. Phylogenetic analysis indicated that the viruses form two different genotypes of ChPyV.
Ilona Deuzing, Zahra Fagrouch, Marlous J Groenewoud, Henk Niphuis, Ivanela Kondova, Willy Bogers, Ernst J Verschoor   +6 more
core   +1 more source

Detection and quantification of classic and emerging viruses by skimmed-milk flocculation and PCR in river water from two geographical areas [PDF]

, 2013
Molecular techniques and virus concentration methods have shown that previously unknown viruses are shed by humans and animals, and may be transmitted by sewage-contaminated water.
Bofill Mas, S., Calgua, B., Fumian, T., Girones, R., Mbayed, Viviana Andrea, Miagostovich, M., Rodríguez Manzano, J., Rusinol, M.   +7 more
core   +1 more source

KIPolyomavirus Sequenses in Respiratory Specimens from Bulgarian Children

Biotechnology & Biotechnological Equipment, 2012
ABSTRACTKI Polyomavirus (KI PyV) has been recently discovered in the respiratory specimens of children and HIV-positive patients. The etiological role of KI PyV in respiratory disease has not been proved yet, but as a member of the polyomavirus family, the virus has oncogenic potential and is probably involved in development of human disease ...
Krassimir Mekouchinov, Metodi Kunchev, Iliya Tsekov, Zlatko Kalvatchev   +3 more
openaire   +1 more source

High‐Throughput Synthesis and Screening of a Cyanimide Library Identifies Selective Inhibitors of ISG15‐Specific Protease mUSP18

Angewandte Chemie, Volume 137, Issue 49, December 1, 2025.
Deubiquitinases (DUBs) and Ub‐like proteases are attractive but challenging drug targets. We developed a high‐throughput synthesis method and prepared a 7536‐member cyanimide DUB‐targeted compound library in 1536‐well plates, using Echo acoustic dispensing. Screening yielded a selective, 35 nM inhibitor of mUSP18, the main ISG15 protease.
Raymond Kooij, Vito Pol, Jin Gan, Bjorn R. van Doodewaerd, Aysegul Sapmaz, Marta Campos Alonso, Günter Fritz, Klaus‐Peter Knobeloch, Paul P. Geurink   +8 more
wiley   +2 more sources