Results 1 to 10 of about 423 (108)

KI and WU Polyomavirus in Respiratory Samples of SARS-CoV-2 Infected Patients [PDF]

Microorganisms, 2021
Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) has been declared a global pandemic. Our goal was to determine whether co-infections with respiratory polyomaviruses, such as Karolinska Institutet polyomavirus (KIPyV) and Washington ...
Valeria Pietropaolo, Ombretta Turriziani, Ugo Moens   +2 more
exaly   +8 more sources

KI and WU Polyomaviruses: Seroprevalence Study and DNA Prevalence in SARS-CoV-2 RNA Positive and Negative Respiratory Samples [PDF]

Microorganisms, 2022
The aim of this work was to study the possible co-infection of KI and WU polyomavirus (KIPyV and WUPyV, respectively) and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in respiratory samples and to detect the seroprevalence of KIPyV and ...
Renátó Kovács, Eszter Csoma, Krisztina Jeles   +2 more
exaly   +6 more sources

Duplex real-time polymerase chain reaction assay for the detection of human KIPyV and WUPyV in nasopharyngeal aspirate pediatric samples [PDF]

Molecular and Cellular Probes, 2018
In this study, we describe a duplex real-time PCR assay for the simultaneous detection of KIPyV and WUPyV polyomaviruses based on TaqMan probes. This assay detected 500 copies/mL both for KIPyV and WUPyV in 100% of tested positive samples.
Maria Carelli, Marco Ligozzi, Erica Diani   +2 more
exaly   +3 more sources

A functional and structural comparative analysis of large tumor antigens reveals evolution of different importin α-dependent nuclear localization signals. [PDF]

Protein Sci
Abstract Nucleocytoplasmic transport regulates the passage of proteins between the nucleus and cytoplasm. In the best characterized pathway, importin (IMP) α bridges cargoes bearing basic, classical nuclear localization signals (cNLSs) to IMPβ1, which mediates transport through the nuclear pore complex.
Cross EM, Akbari N, Ghassabian H, Hoad M, Pavan S, Ariawan D, Donnelly CM, Lavezzo E, Petersen GF, Forwood JK, Alvisi G.   +10 more
europepmc   +2 more sources

Prevalence of DNA of fourteen human polyomaviruses determined in blood donors. [PDF]

Transfusion, 2019
Abstract BACKGROUND Human polyomaviruses (HPyVs), like herpesviruses, cause persistent infection in a large part of the population. In immunocompromised and elderly patients, PyVs cause severe diseases such as nephropathy (BK polyomavirus [BKPyV]), progressive multifocal leukoencephalopathy (JC polyomavirus [JCPyV]), and skin cancer (Merkel cell ...
Kamminga S, van der Meijden E, de Brouwer C, Feltkamp M, Zaaijer H.   +4 more
europepmc   +2 more sources

Trichodysplasia spinulosa: a comprehensive review of the disease and its treatment

Journal of the European Academy of Dermatology and Venereology, Volume 35, Issue 5, Page 1067-1076, May 2021., 2021
Abstract Trichodysplasia spinulosa (TS) is a rare dermatological disease caused by TS‐associated polyomavirus (TSPyV) in immunosuppressed patients. The seroprevalence of TSPyV in immunocompetent adults is high and the number of immunosuppressed patients developing TS remains low, suggesting that TS is underdiagnosed and/or that additional unknown ...
P. Curman, A. Näsman, H. Brauner
wiley   +1 more source

Human Polyomavirus Reactivation: Disease Pathogenesis and Treatment Approaches

Journal of Immunology Research, Volume 2013, Issue 1, 2013., 2013
JC and BK polyomaviruses were discovered over 40 years ago and have become increasingly prevalent causes of morbidity and mortality in a variety of distinct, immunocompromised patient cohorts. The recent discoveries of eight new members of the Polyomaviridae family that are capable of infecting humans suggest that there are more to be discovered and ...
Cillian F. De Gascun, Michael J. Carr, Mario Clerici   +2 more
wiley   +1 more source

Review on the Relationship between Human Polyomaviruses‐Associated Tumors and Host Immune System

Journal of Immunology Research, Volume 2012, Issue 1, 2012., 2012
The polyomaviruses are small DNA viruses that can establish latency in the human host. The name polyomavirus is derived from the Greek roots poly‐, which means “many,” and ‐oma, which means “tumours.” These viruses were originally isolated in mouse (mPyV) and in monkey (SV40).
Serena Delbue, Manola Comar, Pasquale Ferrante, Ludovica Segat   +3 more
wiley   +1 more source

Human Polyomaviruses in Skin Diseases

Pathology Research International, Volume 2011, Issue 1, 2011., 2011
Polyomaviruses are a family of small, nonenveloped viruses with a circular double‐stranded DNA genome of ~5,000 base pairs protected by an icosahedral protein structure. So far, members of this family have been identified in birds and mammals. Until 2006, BK virus (BKV), JC virus (JCV), and simian virus 40 (SV40) were the only polyomaviruses known to ...
Ugo Moens, Maria Ludvigsen, Marijke Van Ghelue, Gerardo Ferrara   +3 more
wiley   +1 more source

Silencing Viral MicroRNA as a Novel Antiviral Therapy?

BioMed Research International, Volume 2009, Issue 1, 2009., 2009
Viruses are intracellular parasites that ensure their existence by converting host cells into viral particle producing entities or into hiding places rendering the virus invisible to the host immune system. Some viruses may also survive by transforming the infected cell into an immortal tumour cell.
Ugo Moens, Bibekanand Mallick
wiley   +1 more source