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Prolonged KI Polyomavirus Infection in Immunodeficient Child [PDF]

open access: yesEmerging Infectious Diseases, 2012
To the Editor: Two novel polyomaviruses (PyVs), KIPyV and WUPyV, were identified in respiratory and fecal specimens from children with signs and symptoms of respiratory tract infection (1,2). A review of literature on emerging viruses in transplant recipients indicated that up to 80% of patients harboring these PyVs are co-infected with another ...
Valeria Falcone   +6 more
doaj   +4 more sources

Small T Oncoprotein of Merkel Cell Polyomavirus Attenuates Cisplatin-Induced Apoptosis and Enhances E1, E6/E7, MMP-1, and Ki-67 Expression in HeLa Cervical Cancer Cells [PDF]

open access: yesAdvanced Pharmaceutical Bulletin
Purpose: Cervical cancer (CxCa) is primarily caused by high-risk human papillomaviruses (hrHPV), which disrupt p53 and pRb regulation, leading to uncontrolled growth and progression.
Fatemeh Pakdel   +3 more
doaj   +3 more sources

KI and WU Polyomaviruses and CD4+ Cell Counts in HIV-1–infected Patients, Italy [PDF]

open access: yesEmerging Infectious Diseases, 2010
To investigate an association between KI and WU polyomavirus (KIPyV and WUPyV) infections and CD4+ cell counts, we tested HIV-1–positive patients and blood donors.
Muhammed Babakir-Mina   +7 more
doaj   +6 more sources

KI and WU Polyomavirus in Respiratory Samples of SARS-CoV-2 Infected Patients [PDF]

open access: yesMicroorganisms, 2021
Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) has been declared a global pandemic. Our goal was to determine whether co-infections with respiratory polyomaviruses, such as Karolinska Institutet polyomavirus (KIPyV) and Washington ...
Carla Prezioso   +15 more
doaj   +5 more sources

KI and WU Polyomavirus detection in tonsils of immunocompetent patients

open access: yesMicrobiologia Medica, 2010
The Polyomaviruses KI and WU have been identified in 2007 in nasopharyngeal aspirates of patients with acute respiratory tract infections.They have been further isolated in faecal samples, lymphoid tissue, bronchoalveolar lavages and blood, although ...
Massimiliano Bergallo   +9 more
doaj   +3 more sources

MCPyV small T antigen enhances HPV16 oncogene expression, promotes Ca Ski cell proliferation, and reduces 5-fluorouracil-induced apoptosis in cervical cancer cells [PDF]

open access: yesInfectious Medicine
Background: Cervical cancer is primarily associated with persistent infection by high-risk human papillomaviruses (HR-HPVs), whose oncoproteins modulate key cellular pathways involved in proliferation and apoptosis.
Tahereh Pakdel   +4 more
doaj   +2 more sources

Whole Genome Sequencing of KI Polyomavirus Strain from Patient with Breast Cancer in Basrah City [PDF]

open access: yesJournal of Bioscience and Applied Research
Background: Polyomaviruses are small, circular, non-enveloped viruses with a diameter of about 40–50 nm, and have a double-stranded DNA molecule descended from the Polyomaviridae. 32 PyV strains are described, more than 10 of which are reported to infect
akeel Alabadi   +2 more
doaj   +2 more sources

Polyomavirus-associated Trichodysplasia spinulosa involves hyperproliferation, pRB phosphorylation and upregulation of p16 and p21. [PDF]

open access: yesPLoS ONE, 2014
Trichodysplasia spinulosa (TS) is a proliferative skin disease observed in severely immunocompromized patients. It is characterized by papule and trichohyalin-rich spicule formation, epidermal acanthosis and distention of dysmorphic hair follicles ...
Siamaque Kazem   +7 more
doaj   +1 more source

Unraveling the Role of Allo-Antibodies and Transplant Injury. [PDF]

open access: yes, 2016
Alloimmunity driving rejection in the context of solid organ transplantation can be grossly divided into mechanisms predominantly driven by either T cell-mediated rejection (TCMR) and antibody-mediated rejection (ABMR), though the co-existence of both ...
Matsuda, Yoshiko, Sarwal, Minnie M
core   +2 more sources

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