KI and WU Polyomavirus detection in tonsils of immunocompetent patients
Microbiologia Medica, 2010 The Polyomaviruses KI and WU have been identified in 2007 in nasopharyngeal aspirates of patients with acute respiratory tract infections.They have been further isolated in faecal samples, lymphoid tissue, bronchoalveolar lavages and blood, although ...
Massimiliano Bergallo +9 more
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MCPyV small T antigen enhances HPV16 oncogene expression, promotes Ca Ski cell proliferation, and reduces 5-fluorouracil-induced apoptosis in cervical cancer cells [PDF]
Infectious MedicineBackground: Cervical cancer is primarily associated with persistent infection by high-risk human papillomaviruses (HR-HPVs), whose oncoproteins modulate key cellular pathways involved in proliferation and apoptosis.
Tahereh Pakdel +4 more
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Prolonged KI Polyomavirus Infection in Immunodeficient Child [PDF]
Emerging Infectious Diseases, 2012 Valeria Falcone +6 more
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Small T Oncoprotein of Merkel Cell Polyomavirus Attenuates Cisplatin-Induced Apoptosis and Enhances E1, E6/E7, MMP-1, and Ki-67 Expression in HeLa Cervical Cancer Cells [PDF]
Advanced Pharmaceutical BulletinPurpose: Cervical cancer (CxCa) is primarily caused by high-risk human papillomaviruses (hrHPV), which disrupt p53 and pRb regulation, leading to uncontrolled growth and progression.
Fatemeh Pakdel +3 more
doaj +2 more sources
ATR inhibition induces NF-κB-dependent immunogenicity in Merkel cell carcinoma independent of cGAS-STING [PDF]
npj Precision OncologyThere is a major unmet need to develop therapies for patients whose tumors do not respond to PD-1 blockade. Inhibition of the ATR-mediated DNA replication checkpoint has been reported to augment antitumor immunity, although the underlying mechanisms ...
Rashmi Bhakuni +12 more
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KI and WU Polyomavirus in Respiratory Samples of SARS-CoV-2 Infected Patients
Microorganisms, 2021 Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) has been declared a global pandemic. Our goal was to determine whether co-infections with respiratory polyomaviruses, such as Karolinska Institutet polyomavirus (KIPyV) and Washington ...
Carla Prezioso +15 more
doaj +1 more source
Polyomavirus-associated Trichodysplasia spinulosa involves hyperproliferation, pRB phosphorylation and upregulation of p16 and p21. [PDF]
PLoS ONE, 2014 Trichodysplasia spinulosa (TS) is a proliferative skin disease observed in severely immunocompromized patients. It is characterized by papule and trichohyalin-rich spicule formation, epidermal acanthosis and distention of dysmorphic hair follicles ...
Siamaque Kazem +7 more
doaj +1 more source
Whole Genome Sequencing of KI Polyomavirus Strain from Patient with Breast Cancer in Basrah City [PDF]
Journal of Bioscience and Applied ResearchBackground: Polyomaviruses are small, circular, non-enveloped viruses with a diameter of about 40–50 nm, and have a double-stranded DNA molecule descended from the Polyomaviridae. 32 PyV strains are described, more than 10 of which are reported to infect
akeel Alabadi +2 more
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Acquisition of Human Polyomaviruses in the First 18 Months of Life
Emerging Infectious Diseases, 2015 We investigated the presence of 4 human polyomaviruses (PyVs) (WU, KI, Merkel cell, and Malawi) in respiratory specimens from a community-based birth cohort. These viruses typically were acquired when children were ≈1 year of age.
Rebecca Rockett +10 more
doaj +1 more source
Clinical epidemiology of bocavirus, rhinovirus, two polyomaviruses and four coronaviruses in HIV-infected and HIV-uninfected South African children. [PDF]
PLoS ONE, 2014 BackgroundAdvances in molecular diagnostics have implicated newly-discovered respiratory viruses in the pathogenesis of pneumonia. We aimed to determine the prevalence and clinical characteristics of human bocavirus (hBoV), human rhinovirus (hRV ...
Marta C Nunes +10 more
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