Results 41 to 50 of about 1,736 (146)

The Prevalence of Human Bocavirus, Human Coronavirus-NL63, Human Metapneumovirus, Human Polyomavirus KI and WU in Respiratory Tract Infections in Kuwait [PDF]

open access: yesMedical Principles and Practice, 2015
<b><i>Objective:</i></b> The aim of this study was to investigate the prevalence of human coronavirus (HCoV)-NL63, human metapneumovirus (hMPV), human bocavirus (Boca), human polyomavirus KI (KIV) and human polyomavirus WU (WUV) in respiratory tract infections (RTI) in Kuwait.
Essa, Sahar   +5 more
openaire   +2 more sources

A Case of Late Onset and Rapidly Progressive Central Nervous System Post‐transplant Lymphoproliferative Disorder

open access: yesCase Reports in Oncological Medicine, Volume 2026, Issue 1, 2026.
Background Post‐transplant lymphoproliferative disorder (PTLD) is a rare but serious complication of chronic immunosuppression in transplant recipients. Although previously thought to occur primarily in the first year post‐transplant, emerging data suggests a second peak in incidence in those who survive greater than 10 years after transplantation ...
Ghadi Ghanem   +3 more
wiley   +1 more source

The Role of APOBEC3B in Cancer: Mechanisms, Clinical Challenges, and Therapeutic Opportunities

open access: yesHuman Mutation, Volume 2026, Issue 1, 2026.
Apolipoprotein B mRNA editing enzyme catalytic polypeptide‐like 3B (APOBEC3B, A3B) is a key cytidine deaminase that induces genomic instability and clonal evolution in diverse malignancies. Although A3B plays a key role in the onset and advancement of various cancers, a comprehensive model bridging its multifaceted mechanisms and clinical translation ...
Fengfeng Zhou   +3 more
wiley   +1 more source

KIPolyomavirus Sequenses in Respiratory Specimens from Bulgarian Children

open access: yesBiotechnology & Biotechnological Equipment, 2012
ABSTRACTKI Polyomavirus (KI PyV) has been recently discovered in the respiratory specimens of children and HIV-positive patients. The etiological role of KI PyV in respiratory disease has not been proved yet, but as a member of the polyomavirus family, the virus has oncogenic potential and is probably involved in development of human disease ...
Krassimir Mekouchinov   +3 more
openaire   +1 more source

Cytomegalovirus infection is common in prostate cancer and antiviral therapies inhibit progression in disease models

open access: yesMolecular Oncology, Volume 19, Issue 11, Page 3035-3059, November 2025.
Human cytomegalovirus infection is common in normal prostate epithelium, prostate tumor tissue, and prostate cancer cell lines. CMV promotes cell survival, proliferation, and androgen receptor signaling. Anti‐CMV pharmaceutical compounds in clinical use inhibited cell expansion in prostate cancer models in vitro and in vivo, motivating investigation ...
Johanna Classon   +13 more
wiley   +1 more source

The Epidemiology of Neuroendocrine Carcinomas in Taiwan: A Population‐Based Cancer Registry Study

open access: yesCancer Medicine, Volume 14, Issue 21, November 2025.
Differences in the incidence trends and clinical outcomes of NECs suggest different etiologies and heterogeneities of NECs. Further investigations on risk factor identification and novel treatment strategies for NECs are warranted. ABSTRACT Background Lung and small cell neuroendocrine carcinomas (SCCs) are the most common sites and histological types ...
Yi‐Hsin Yang   +5 more
wiley   +1 more source

The microbiome in cancer

open access: yesiMeta, Volume 4, Issue 5, October 2025.
This comprehensive review elucidates the transformative role of the human microbiome in cancer biology, revealing innovative mechanistic insights into the intricate tumor–microbe interactions across diverse organ systems. This work highlights the clinical and translational value of novel microbiome‐based biomarkers for early detection, prognosis, and ...
Anqi Lin   +50 more
wiley   +1 more source

Pleural Mesothelioma: Pathogenesis, Diagnosis, Treatment, Prognosis, and Survival

open access: yesMedComm, Volume 6, Issue 9, September 2025.
This is an overview of current and emerging therapeutic strategies for pleural mesothelioma (PM), including chemotherapy, immunotherapy (ICIs, dendritic cell vaccines, CAR‐T therapy), anti‐angiogenic therapy, epigenetic modifications (DNA methylation, histone changes, non‐coding RNAs), and targeted therapy focusing on genomic alterations and signaling ...
Libo Zhang, Meijuan Huang
wiley   +1 more source

Advances in Single‐Cell Sequencing for Infectious Diseases: Progress and Perspectives

open access: yesAdvanced Science, Volume 12, Issue 32, August 28, 2025.
Single‐cell sequencing technologies uncover novel, unknown, and emergent features of many diseases. This review describes recent progress of single‐cell sequencing technologies and their applications in infectious diseases, summarizes the underlying commonalities of different infections and discusses future research directions, facilitating the ...
Mengyuan Lyu   +13 more
wiley   +1 more source

First‐In‐Human, Randomized, Placebo‐Controlled, SAD and MAD Trial to Evaluate Safety, Tolerability, and PK/PD Modeling of Potravitug in Healthy Adults

open access: yesClinical and Translational Science, Volume 18, Issue 8, August 2025.
ABSTRACT BK polyomavirus (BKPyV) affects 10%–30% of kidney‐transplant recipients receiving immunosuppressive therapy, potentially leading to nephropathy, graft dysfunction, graft loss, and increased mortality. Despite the medical need, no targeted therapies exist.
Marcus May   +8 more
wiley   +1 more source

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