Results 61 to 70 of about 469,658 (145)

First‐In‐Human, Randomized, Placebo‐Controlled, SAD and MAD Trial to Evaluate Safety, Tolerability, and PK/PD Modeling of Potravitug in Healthy Adults

Clinical and Translational Science, Volume 18, Issue 8, August 2025.
ABSTRACT BK polyomavirus (BKPyV) affects 10%–30% of kidney‐transplant recipients receiving immunosuppressive therapy, potentially leading to nephropathy, graft dysfunction, graft loss, and increased mortality. Despite the medical need, no targeted therapies exist.
Marcus May, Julia K. Bialek‐Waldmann, Andrew Wright, Scott Gruver, Joshuaine Grant, Barbara Eicher, Jemima Seidenberg, Gerald P. Parzmair, Juergen Beck   +8 more
wiley   +1 more source

A Rare Case of Parvovirus Infection Causing Pure Red Cell Aplasia in a Kidney‐Pancreas Transplant Recipient

Nephrology, Volume 30, Issue 7, July 2025.
ABSTRACT Parvovirus B19 infection can rarely manifest with pure red cell aplasia in immunocompromised hosts. This case details a 48‐year‐old male, 11 years post kidney‐pancreas transplant who was admitted with a chronic normocytic anaemia (haemoglobin 72 g/L) after being admitted four months prior with a bleeding peptic ulcer, requiring eight units of ...
Oscar Perry, Robert Ellis, Sanjana Dang, George T. John, Stephanie Hendry, Monica Suet Ying Ng   +5 more
wiley   +1 more source

Impact of Psychological Stress and Spontaneous Tumour Regression on the Hippocampal Proteome in a Mouse Model of Breast Cancer

Journal of Neurochemistry, Volume 169, Issue 4, April 2025.
This study examines how breast cancer and psychological stress impact the hippocampal proteome, uncovering altered signalling pathways linked to mitochondrial dysfunction, impaired energy production, and altered synaptic plasticity; that is, cellular processes that are critical for memory formation and cognitive health.
Myrthe Mampay, Gheed Al‐Hity, Sara O. Rolle, Walla Alzboon, Nicolas A. Stewart, Melanie S. Flint, Graham K. Sheridan   +6 more
wiley   +1 more source

Persistence of polyomavirus : versus immunity to polyoma tumors

, 1997
The aim of this thesis was to understand the role of different specific immune effectors with regard to polyomavirus persistence and polyomavirus induced tumor development.
Zsofia Berke (19525291)
core   +1 more source

Genome Sequences of a Rat Polyomavirus Related to Murine Polyomavirus, Rattus norvegicus Polyomavirus 1 [PDF]

, 2015
We amplified and sequenced six complete genomes of a polyomavirus from feral Norway rats (Rattus norvegicus) and from a long-term breeding colony derived from Norway rats.
Richter, Dania, Ulrich, Rainer G., Matuschka, Franz-Rainer, Ehlers, Bernhard   +3 more
core   +1 more source

Ki-67 analysis.

, 2018
A: DAPI Image. B: Segmented Nuclei. C: Ki-67 staining image (CY5 Channel). D: Binarized Ki-67 Stain. E: Overlap of B and D, to identify Ki-67+ nuclei (white arrows) and Ki-67- nuclei (red arrows). Scale bars = 50 microns.
Inês Godet (6160553), Daniele M. Gilkes (4836423), Josh W. DiGiacomo (6160556), Soumitra Bhoyar (6160550)   +3 more
core   +1 more source

Ki-67 is a PP1-interacting protein that organises the mitotic chromosome periphery [PDF]

, 2014
Copyright @ 2014 Booth et al. This article is distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use and redistribution provided that the original author and source are credited.When the nucleolus ...
Elizabeth Petfalski, Vagnarelli, Paola, Ponting, Christopher, David Tollervey, Earnshaw, William C, Imamoto, N, Petfalski, Elizabeth, Sanchez-Pulido, Luis, Giulia Vargiu, Takagi, M, Booth, DG, Luis Sanchez-Pulido, Tollervey, David, Ponting, Chris P, Petfalski, E, Ponting, CP, Vargiu, Giulia, Tollervey, D, Naoko Imamoto, Ponting, Chris P.; id_orcid, Earnshaw, William C., Daniel G Booth, Vagnarelli, P, Kumiko Samejima, Imamoto, Naoko, Booth, Daniel G, William C Earnshaw, Masatoshi Takagi, Samejima, Kumiko, Sanchez-Pulido, L, Vargiu, G, Booth, Daniel G., Chris P Ponting, Paola Vagnarelli, Takagi, Masatoshi, Samejima, K, Earnshaw, WC   +36 more
core   +1 more source

Similarity among SV40-specific Tag mimotopes (Pep Tag A and Pep Tag D) and other polyomavirus Tag sequences, Panel A and B, respectively.

, 2016
SV40 (simian virus 40) Tag sequences were compared to the Tags of the following polyomaviruses: BKV (BKPyV, BK polyomavirus), HPyV6 (human polyomavirus 6), HPyV7 (human polyomavirus 7), HPyV9 (human polyomavirus 9), HPyV10 (human polyomavirus 10), HPyV11/
Lorenzo Trevisiol (843507), Giuseppe Barbanti-Brodano (407141), Angelo Taronna (407131), Janet S. Butel (584537), Emanuela Vaccher (694122), Alfredo Corallini (407133), Mauro Tognon (311647), Fernanda Martini (407142), Ilaria Bononi (407134), Marco Manfrini (843506), Silvia Pietrobon (407135), Elisa Mazzoni (407132)   +11 more
core   +1 more source

KI-LOK - Prüfverfahren für KI-basierte Komponenten im Eisenbahnbetrieb

Bestehende Verifikations- und Validierungsmethoden für KI-Systeme stoßen insbesondere bei sicherheitskritischen Anwendungen an ihre Grenzen, da sie die spezifischen Herausforderungen von Black-Box-Modellen und kontinuierlich lernenden Systemen ...
Knoblauch, Dorian, Beiker, Henry, Viehmann, Johannes, Großmann, Jürgen, Kharma, Sami   +4 more
core   +1 more source

Goose haemorrhagic polyomavirus infection in ducks [PDF]

, 2008
J-L. Guérin, Boucraut-Baralon, Corine, Guérin, Jean-Luc, Pingret, J-l, J-L. Pingret, C. Boucraut-Baralon   +5 more
core   +1 more source