Results 61 to 70 of about 3,591 (186)

Assessment of 19 Genes and Validation of CRM Gene Panel for Quantitative Transcriptional Analysis of Molecular Rejection and Inflammation in Archival Kidney Transplant Biopsies. [PDF]

, 2019
Background: There is an urgent need to develop and implement low cost, high-throughput standardized methods for routine molecular assessment of transplant biopsies.
Dobi, Dejan, Junger, Henrik, Laszik, Zoltan, Liberto, Juliane, Nguyen, Mark, Sarwal, Minnie M, Sigdel, Tara, Vincenti, Flavio   +7 more
core  

Inhibition of Simian Virus 40 replication by targeting the molecular chaperone function and ATPase activity of T antigen [PDF]

, 2009
Polyomaviruses such as BK virus and JC virus have been linked to several diseases, but treatments that thwart their propagation are limited in part because of slow growth and cumbersome culturing conditions.
Brodsky, JL, Fanning, E, Fewell, SW, Ishwad, C, Lingwood, CA, Pipas, JM, Seguin, SP, Vats, A, Wipf, P, Wright, CM, Zhang, H   +10 more
core   +1 more source

The microbiome in cancer

iMeta, Volume 4, Issue 5, October 2025.
This comprehensive review elucidates the transformative role of the human microbiome in cancer biology, revealing innovative mechanistic insights into the intricate tumor–microbe interactions across diverse organ systems. This work highlights the clinical and translational value of novel microbiome‐based biomarkers for early detection, prognosis, and ...
Anqi Lin, Minying Xiong, Aimin Jiang, Lihaoyun Huang, Hank Z. H. Wong, Suyin Feng, Chunyan Zhang, Yu Li, Li Chen, Hao Chi, Pengpeng Zhang, Bicheng Ye, Hengguo Zhang, Nan Zhang, Lingxuan Zhu, Weiming Mou, Junyi Shen, Kailai Li, Wentao Xu, Haoxuan Ying, Cangang Zhang, Dongqiang Zeng, Jindong Xie, Xinpei Deng, Qi Wang, Jianying Xu, Wenjie Shi, Chang Qi, Chunrun Qu, Xufeng Huang, András Hajdu, Chaoqun Li, Changmin Peng, Xuanye Cao, Guangsheng Pei, Lin Zhang, Yujia Huo, Jiabao Xu, Antonino Glaviano, Attila Gábor Szöllősi, Sicheng Bian, Zhengrui Li, Hailin Tang, Bufu Tang, Zaoqu Liu, Jian Zhang, Kai Miao, Quan Cheng, Ting Wei, Shuofeng Yuan, Peng Luo   +50 more
wiley   +1 more source

Avian polyomavirus: a recent update [PDF]

, 2017
Avian polyomavirus disease is among the most common viral diseases of domesticated exotic birds as such in psittacine families. Caused by avian polyomavirus (APV) which possess a circular, double-stranded DNA which encodes for major structural virus ...
Abdul Razak, Mariatulqabtiah, Abu, Jalila, Mohd Padzil, Muhamad Faiz   +2 more
core  

Human bocavirus (HBoV) in children with respiratory tract infection by enzyme linked immunosorbent assay (ELISA) and qualitative polymerase chain reaction (PCR) [PDF]

, 2011
Background Human bocavirus (HBoV) is a recently discovered parvovirus associated with mild to severe lower respiratory tract infections in children, the aim of the work was determination of human bocavirus in nasopharyngeal aspirate (NPA) of infants by ...
Mona Z Zaghloul
core   +1 more source

Pleural Mesothelioma: Pathogenesis, Diagnosis, Treatment, Prognosis, and Survival

MedComm, Volume 6, Issue 9, September 2025.
This is an overview of current and emerging therapeutic strategies for pleural mesothelioma (PM), including chemotherapy, immunotherapy (ICIs, dendritic cell vaccines, CAR‐T therapy), anti‐angiogenic therapy, epigenetic modifications (DNA methylation, histone changes, non‐coding RNAs), and targeted therapy focusing on genomic alterations and signaling ...
Libo Zhang, Meijuan Huang
wiley   +1 more source

A new strategy for the treatment of viral infections [PDF]

, 2006
Intact viruses, containing no viral genome but which are loaded with a therapeutic drug or virus like particles loaded with antiviral drugs are potentially selective drug carriers for the intracellular delivery of therapeutics.
Wolf, Markus
core   +1 more source

Advances in Single‐Cell Sequencing for Infectious Diseases: Progress and Perspectives

Advanced Science, Volume 12, Issue 32, August 28, 2025.
Single‐cell sequencing technologies uncover novel, unknown, and emergent features of many diseases. This review describes recent progress of single‐cell sequencing technologies and their applications in infectious diseases, summarizes the underlying commonalities of different infections and discusses future research directions, facilitating the ...
Mengyuan Lyu, Yang Liu, Jian Zhou, Hongli Lai, Hongxia Ruan, Dongsheng Wu, Shun Zhu, Xudong Zhou, Wananqi Ma, Yuchen Huang, Shuting Lei, Han Luo, Jie Chen, Binwu Ying   +13 more
wiley   +1 more source

Chronic Viral Infection and Primary Central Nervous System Malignancy [PDF]

, 2010
Primary central nervous system (CNS) tumors cause significant morbidity and mortality in both adults and children. While some of the genetic and molecular mechanisms of neuro-oncogenesis are known, much less is known about possible epigenetic ...
Robert Saddawi-Konefka, John R. Crawford, JR Abend, N Ahsan, RR Arthur, J Baillie, G Barbanti-Brodano, G Barbanti-Brodano, G Barbanti-Brodano, M Benko, DJ Bergsagel, G Bogdanovic, R Boldorini, R Boldorini, ML Bondy, KA Boyle, JS Butel, R Caldarelli-Stefano, M Carbone, MT Caserta, PK Chan, J Cinatl Jr, J Cinatl Jr, J Cinatl Jr, J Cinatl Jr, J Cinatl, DA Clark, CS Cobbs, CS Cobbs, CS Cobbs, A Corallini, JR Crawford, JR Crawford, S Croul, L Cuomo, T Dalianis, AJ Davison, L Bolle De, M Mattei De, FB Dean, L Valle Del, L Valle Del, L Valle Del, L Valle Del, L Valle Del, A Dolan, CG Duncan, K Dorries, DW Ellison, EA Engels, D Fioriti, L Flamand, RL Garcea, RL Garcea, SD Gardner, AF Gazdar, VS Goldmacher, ML Gulley, CB Hall, CB Hall, CB Hall, MS Hamza, KF Harris, H Hayashi, SD Hayward, U Hohlweg, A Hossain, H Huang, AJ Hume, B Jasani, FM Jault, RT Javier, M Jiang, RA Johnson, RA Johnson, RA Johnson, F Kashanchi, JY Kim, DW Kimberlin, G Klein, WA Knowles, K Kosulin, T Kouhata, P Krieg, B Krynska, SK Lau, JA Lednicky, W Lee, JB Liao, WT London, WT London, M Luppi, MS Maginnis, T Maisch, EO Major, F Martini, AL McCormick, DJ McGeoch, W Meinke, M Michaelis, M Michaelis, G Miller, NR Miller, DA Mitchell, LB Nabors, M Negrini, AM Neves, V Nunbhakdi-Craig, H Okamoto, T Okuno, MB Oldstone, BL Padgett, DM Parkin, G Perez-Liz, S Pina-Oviedo, JM Pipas, S Poltermann, RM Prins, J Rajcani, FA Ray, A Rencic, HA Rogers, DE Rollison, DE Rollison, JJ Rushton, J Sabatier, ME Scheurer, M Scholz, T Shenk, T Shenk, T Shibutani, DT Simmons, A Skaletskaya, YJ Song, L Soroceanu, N Stewart, K Straat, K Tabuchi, K Tabuchi, M Tognon, C Trabanelli, RK Vasishta, A Volpi, DL Walker, X Wang, S Weggen, E White, MK White, M Wrensch, M Wrensch, M Wrensch, M Wrensch, Y Yabe, K Yamanishi, Y Yogo, T Yoshikawa, Y Yu, DM Zerr, H Hausen zur   +158 more
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First‐In‐Human, Randomized, Placebo‐Controlled, SAD and MAD Trial to Evaluate Safety, Tolerability, and PK/PD Modeling of Potravitug in Healthy Adults

Clinical and Translational Science, Volume 18, Issue 8, August 2025.
ABSTRACT BK polyomavirus (BKPyV) affects 10%–30% of kidney‐transplant recipients receiving immunosuppressive therapy, potentially leading to nephropathy, graft dysfunction, graft loss, and increased mortality. Despite the medical need, no targeted therapies exist.
Marcus May, Julia K. Bialek‐Waldmann, Andrew Wright, Scott Gruver, Joshuaine Grant, Barbara Eicher, Jemima Seidenberg, Gerald P. Parzmair, Juergen Beck   +8 more
wiley   +1 more source