Results 81 to 90 of about 3,591 (186)

Exploring New Frontiers: Alternative Breast Cancer Treatments Through Glycocalyx Research

The Breast Journal, Volume 2025, Issue 1, 2025.
Breast cancer (BC) treatment is developing toward more precise and personalized care through the approval of different comprehensive approaches. Clinical practice emphasizes significant patient‐to‐patient variability in treatment response among patients, even those with similar clinical and biological profiles. Recent studies have demonstrated that the
Ielizaveta Gorodetska, Anastasiia Samusieva, Tetiana Lahuta, Olga Ponomarova, Oleg Socha, Iryna Kozeretska, Karuna Sharma   +6 more
wiley   +1 more source

Spatial heterogeneity and peptide availability determine CTL killing efficiency in vivo [PDF]

, 2014
The rate at which a cytotoxic T lymphocyte (CTL) can survey for infected cells is a key ingredient of models of vertebrate immune responses to intracellular pathogens. Estimates have been obtained using in vivo cytotoxicity assays in which peptide-pulsed
A Wiedemann, A Yates, AJ Yates, AL DeVico, AM Beal, AM Byers, Andrew Yates, AS Perelson, AS Perelson, AS Perelson, AS Perelson, B Breart, Benedict Seddon, Bjoern Peters, CA Macken, D Zagury, DH Busch, DL Barber, EA Grimm, ER Christinck, F Graw, F Graw, G Chu, LG Guidotti, M Bajénoff, M Poe, MA Purbhoo, MH Foley, MR Jenkins, P Perez, RR Regoes, RR Regoes, S Budhu, S Valitutti, SE Henrickson, SH van der Burg, Sim Tung, Thea Hogan, TR Mempel, Ulrich Kadolsky, VV Ganusov, VV Ganusov, VV Ganusov, VV Ganusov, W Barchet, Y Sykulev, YW Jung   +46 more
core   +4 more sources

Virus entry at a glance [PDF]

, 2013
The goal of a virus particle is to transport its genome in a replication-competent form from an infected cell to an uninfected cell. To enter a new host cell, the majority of viruses take advantage of the endocytic mechanisms of the cell and wait until ...
Helenius, Ari, Yamauchi, Yohei
core   +4 more sources

First Documented Case of BK Nephropathy in Kidney Transplant Recipient in Croatia: Usage of Urine Cytology in Evaluation Process [PDF]

, 2010
BK virus associated nephropathy (BKVAN) in transplanted kidney, although recognized as a distinct entity in the 1970-es, continues to represent a challenge in kidney transplantation, mainly because the optimal treatment approach has not been determined ...
Danica Ljubanović, Ika Kardum-Skelin, Ivana Kovačević Vojtušek, Mirjana Sabljar Matovinović, Mladen Knotek, Sonja Gracin   +5 more
core   +1 more source

Src Inhibition Blocks c-Myc Translation and Glucose Metabolism to Prevent the Development of Breast Cancer [PDF]

, 2015
Preventing breast cancer will require the development of targeted strategies that can effectively block disease progression. Tamoxifen and aromatase inhibitors are effective in addressing estrogen receptor–positive (ER+) breast cancer development, but ...
Ambrose, Adrian, Arun, Banu K., Brady, Samuel W., Chang, Chia-Chi, Dobbs, Jessica, Ibarra-Drendall, Catherine, Jain, Shalini, Jia, Wei, Kyrish, Matt, Li, Ping, Richards-Kortum, Rebecca, Seewaldt, Victoria L., Sistrunk, Christopher, Tkaczyk, Tomasz S., Wang, Hai, Wang, Xiao, Yu, Dihua, Zhang, Qingling, Zhao, Hong   +18 more
core   +2 more sources

The Value of Urinary Decoy Cells Finding in Patients with Kidney Transplantation [PDF]

, 2010
Childhood infection with polyomaviruses leads to a life-long latent infection of renal and urinary tract epithelia. Replication in the reno-urinary epithelium is associated with viral cytopathic changes such as nuclear inclusions and decoy cells.
Arijana Pačić, Franjo Jurenec, Ika Kardum-Skelin, Maja Mišić, Mladen Knotek, Željko Vidas   +5 more
core   +1 more source

Genome editing technologies to fight infectious diseases [PDF]

, 2017
Genome editing by programmable nucleases represents a promising tool that could be exploited to develop new therapeutic strategies to fight infectious diseases.
Barzon, Luisa, Pal\ue3\ub9, Giorgio, Trevisan, Marta   +2 more
core   +1 more source

Characterization of the non-coding control region of polyomavirus KI isolated from nasopharyngeal samples from patients with respiratory symptoms or infection and from blood from healthy blood donors in Norway

Journal of General Virology, 2016
Seroepidemiological studies showed that the human polyomavirus KI (KIPyV) is common in the human population, with age-specific seroprevalence ranging from 40-90 %. Genome epidemiological analyses demonstrated that KIPyV DNA is predominantly found in respiratory tract samples of immunocompromised individuals and children suffering from respiratory ...
Song, Xiaobo, Van Ghelue, Marijke, Ludvigsen, Maria A., Nordbø, Svein Arne, Ehlers, Bernhard, Moens, Ugo   +5 more
openaire   +3 more sources

The glial growth factors deficiency and synaptic destabilization hypothesis of schizophrenia [PDF]

, 2002
Background A systems approach to understanding the etiology of schizophrenia requires a theory which is able to integrate genetic as well as neurodevelopmental factors.
A Sawa, II Gottesman, HW Moises, II Gottesman, RM Murray, S Marenco, HWM Moises, DA Lewis, CS Monk, SJ Webb, G Lemke, DR Cotter, Y Hakak, M Rothermundt, DR Lara, NM Williams, AB Goodman, ABr Niculescu, K Mirnics, S Burden, A Buonanno, H Song, PG Haydon, A Araque, SJ Morley, O Steward, EM Schuman, L Fromm, P Bezzi, YZ Huang, ES Anton, V Calaora, D Wolpowitz, JA Loeb, K Adlkofer, JY Wang, MA Olayioye, Y Liu, MK Sapru, DE Syroid, CM Hertig, C Sweeney, LA Scheving, R Li, MP Allen, S Goruppi, R Eilam, GS Naeve, P Subramony, JS Cameron, H Thoenen, M Canossa, U Otten, M Canossa, E Alleva, RR Baliga, M Kleijn, DG Wells, ER Kandel, M Shelly, R Gerlai, JC Conover, JP Wagner, AL Boxer, DM Araujo, EC Beattie, R Hemi, A Carrie, JH Pak, H Häfner, J Klosterkötter, WIB Beveridge, S Leonard, R Freedman, J Williams, N Iwata, E Jonsson, RS Devon, J Wei, HW Moises, V Dror, H Liu, A Chakravarti, KV Chowdari, S Wang, R Meller, SG Thompson, KM Druey, C Rio, A Araque, R Freedman, K O'Donnell, JR Florini, VK Han, YS Nakamura, A Dupont, M Saku, EF Torrey, N Giannoukakis, H Sasaki, L Magnaghi-Jaulin, W Lin, JW Crayton, J-Stanton Ross, DH Mathalon, H Thoenen, C Frith, VL Nimgaonkar, M Avila, S Jones, LF Kastrukoff, B Schweighardt, AV Albright, JE Friedman, PB Challoner, DA Clark, S Bofill-Mas, EO Major, J Gordon, A Tretiakova, S Bofill-Mas, KM Weiss, JR Kidd, D Wang, AD Long, LB Jorde, DF Levinson, JA Badner, J Altmüller, NJ Risch, M Wudarsky, RG Petty, H Wetzel, G Grunder, CJ Bench, K Otani, KM Yazici, KI Melkersson, KI Melkersson, A Petronis, EF Torrey, JS Kim, JW Olney, SE Antonarakis, V Arolt, U Bailer, CL Barr, JL Blouin, LM Brzustowicz, Q Cao, J Collinge, H Coon, H Coon, TJ Crow, J Dann, LE DeLisi, LE DeLisi, J Ekelund, SV Faraone, DL Garver, M Gill, HM Gurling, I Hovatta, CA Kaufmann, KS Kendler, VK Lasseter, DF Levinson, DF Levinson, MW Lin, MW Lin, E Lindholm, M Maziade, M Maziade, HW Moises, S Nanko, T Paunio, AE Pulver, AE Pulver, AE Pulver, MI Rees, BP Riley, SG Schwab, SG Schwab, SG Schwab, SG Schwab, SG Schwab, SG Schwab, SH Shaw, R Sherrington, JM Silverman, D St Clair, G Stöber, RE Straub, RE Straub, RE Straub, WJ Turner, HP Vallada, S Wang, DB Wildenauer, NM Williams, E Lander, V Chalifa-Caspi, II Gottesman, JM Tanner, HT Chugani, MR Cohen   +205 more
core   +1 more source

Ο ρόλος των ιών corona NL63 και HKU1, parainfluenza 4, polyomavirus WU και KI και των εντεροϊών σε παιδιά με λοιμώξεις του αναπνευστικού συστήματος

, 2021
Οι λοιμώξεις του αναπνευστικού συστήματος είναι από τις πιο συνηθισμένες ασθένειες παγκοσμίως, προκαλώντας σημαντικό ποσοστό νοσηρότητας και θνησιμότητας στους ανθρώπους. Η παρούσα διδακτορική διατριβή είχε ως σκοπό την ανάπτυξη και βελτιστοποίηση μοριακών μεθόδων για τη διερεύνηση της συμμετοχής των αναπνευστικών ιών κορόνα NL63 και HKU1, της ...
openaire   +1 more source