Results 11 to 20 of about 602 (121)

A functional and structural comparative analysis of large tumor antigens reveals evolution of different importin α-dependent nuclear localization signals. [PDF]

Protein Sci
Abstract Nucleocytoplasmic transport regulates the passage of proteins between the nucleus and cytoplasm. In the best characterized pathway, importin (IMP) α bridges cargoes bearing basic, classical nuclear localization signals (cNLSs) to IMPβ1, which mediates transport through the nuclear pore complex.
Cross EM, Akbari N, Ghassabian H, Hoad M, Pavan S, Ariawan D, Donnelly CM, Lavezzo E, Petersen GF, Forwood JK, Alvisi G.   +10 more
europepmc   +2 more sources

The occurrence of polyomaviruses WUPyV and KIPyV among patients with severe respiratory infections. [PDF]

Braz J Microbiol, 2019
In 2007, the new polyomaviruses WUPyV and KIPyV were identified in patients with acute respiratory infections. The aim of this study was to investigate these viruses in hospitalized patients with severe acute respiratory infection (SARI). A retrospective study was conducted with 251 patients, from April 2009 to November 2010, using nasopharyngeal ...
Caldeira DB, de Souza Luna LK, Watanabe A, Perosa AH, Granato C, Bellei N.   +5 more
europepmc   +4 more sources

Prevalence of DNA of fourteen human polyomaviruses determined in blood donors. [PDF]

Transfusion, 2019
Abstract BACKGROUND Human polyomaviruses (HPyVs), like herpesviruses, cause persistent infection in a large part of the population. In immunocompromised and elderly patients, PyVs cause severe diseases such as nephropathy (BK polyomavirus [BKPyV]), progressive multifocal leukoencephalopathy (JC polyomavirus [JCPyV]), and skin cancer (Merkel cell ...
Kamminga S, van der Meijden E, de Brouwer C, Feltkamp M, Zaaijer H.   +4 more
europepmc   +2 more sources

Serologic Evidence of Frequent Human Infection with WU and KI Polyomaviruses [PDF]

Emerging Infectious Diseases, 2009
WU polyomavirus (WUPyV) and KI polyomavirus (KIPyV) are novel human polyomaviruses. They were originally identified in human respiratory secretions, but the extent of human infection caused by these viruses has not been described to date.
Nang L. Nguyen, Binh-Minh Le, David Wang
doaj   +5 more sources

Antibody responses to common viruses according to COVID-19 severity and postacute sequelae of COVID-19 [PDF]

Journal of Medical Virology, Volume 96, Issue 9, September 2024.
Limited research suggests that certain viruses reactivate in severe-acute-respiratory-syndrome-coronavirus 2 infection, contributing to the development of postacute sequelae of COVID-19 (PASC).
Aguilar, R., Bañuls, M., Castaño-Vinyals, Gemma, de Cid, Rafael, Dobaño, C., Espinosa, Ana, Garcia-Aymerich, J., Iraola-Guzmán, Susana, Jiménez, A., Karachaliou, Marianna, Kogevinas, M, Moncunill, G., Nogués, E.A., Ranzani, O., Universitat Autònoma de Barcelona, Vidal, M.   +15 more
core   +2 more sources

Current and Future Point-of-Care Tests for Emerging and New Respiratory Viruses and Future Perspectives [PDF]

Frontiers in Cellular and Infection Microbiology, 2020
The availability of pathogen-specific treatment options for respiratory tract infections (RTIs) increased the need for rapid diagnostic tests. Besides, retrospective studies, improved lab-based detection methods and the intensified search for new viruses
Philipp P. Nelson, Barbara A. Rath, Barbara A. Rath, Barbara A. Rath, Paraskevi C. Fragkou, Paraskevi C. Fragkou, Emmanouil Antalis, Sotirios Tsiodras, Sotirios Tsiodras, Chrysanthi Skevaki, Chrysanthi Skevaki   +10 more
doaj   +2 more sources

Prevalence of Polyomaviruses in Polish patients [PDF]

Current Issues in Pharmacy and Medical Sciences, 2014
The aim of our study was to investigate the prevalence of new polyomaviruses KIPyV and WUPyV in the Polish population in the Lublin region. In it, we demonstrated that the prevalence of this viruses is low - 1.1% WU and 3.4% KI.
Badura Marzena, Dworzanski Jakub, Polz Anna, Polz-Dacewicz Malgorzata   +3 more
doaj   +3 more sources

HPyV6 and HPyV7 in urine from immunocompromised patients. [PDF]

Virol J, 2021
Background - Human polyomavirus 6 (HPyV6) and HPyV7 are two of the novel polyomaviruses that were originally detected in non-diseased skin. Serological studies have shown that these viruses are ubiquitous in the healthy adult population with ...
Prezioso C, Van Ghelue M, Moens U, Pietropaolo V.   +3 more
europepmc   +4 more sources

Seroepidemiology of maternal and childhood pathogen exposure in three European mother-child cohorts [PDF]

International Journal of Infectious Diseases
Objectives: To describe the epidemiology of common pathogens and risk factors among pregnant women and their children. Methods: In three European population-based birth cohorts, we examined 2213 mother-child pairs, contributing 5036 blood samples from ...
Marianna Karachaliou, Marta Vidal, Lucy Pembrey, Mariona Bustamante, Ana Espinosa, Dan Mason, Marc Bañuls, Delphine Casabonne, Theano Roumeliotaki, Vicky Bempi, Natalia Marin, Juana Maria Delgado-Saborit, Santa Marina Rodríguez Loreto, Jesús Ibarluzea, Martine Vrijheid, Ruth Aguilar, Carlota Dobaño, Manolis Kogevinas   +17 more
doaj   +4 more sources

Trichodysplasia spinulosa: a comprehensive review of the disease and its treatment

Journal of the European Academy of Dermatology and Venereology, Volume 35, Issue 5, Page 1067-1076, May 2021., 2021
Abstract Trichodysplasia spinulosa (TS) is a rare dermatological disease caused by TS‐associated polyomavirus (TSPyV) in immunosuppressed patients. The seroprevalence of TSPyV in immunocompetent adults is high and the number of immunosuppressed patients developing TS remains low, suggesting that TS is underdiagnosed and/or that additional unknown ...
P. Curman, A. Näsman, H. Brauner
wiley   +1 more source