Results 31 to 40 of about 3,213,084 (261)

Dual mTOR/PI3K inhibition limits PI3K-dependent pathways activated upon mTOR inhibition in autosomal dominant polycystic kidney disease [PDF]

, 2018
Autosomal dominant polycystic kidney disease (ADPKD) is characterized by the development of kidney cysts leading to kidney failure in adulthood. Inhibition of mammalian target of rapamycin (mTOR) slows polycystic kidney disease (PKD) progression in ...
Arcaro, Alexandre, Castelletti, Deborah, Fu, Xuebin, Liu, Yang, Mischak, Harald, Mullen, William, Pejchinovski, Martin, Serra, Andreas L., Siwy, Justyna, Wang, Xueqi, Watnick, Terry J.   +10 more
core   +2 more sources

A Rare Case Report of Giant Urinary Bladder Stone Causing Recurrent Dysuria in a Woman

Case Reports in Urology, 2022
Background. Large urinary bladder stones are not common and even less common in females. We report a case of large bladder stone presented with acute retention of urine in a female patient. Case Report.
Rojan Adhikari, Hari Prasad Baral, Utsav Bhattarai, Ravi Kiran Gautam, Kiran Jung Kunwar, Dipesh Shrestha, Bijay Mansingh Katwal   +6 more
doaj   +1 more source

Anion transporter: highly cell-type-specific expression of distinct polypeptides and transcripts in erythroid and nonerythroid cells [PDF]

, 1985
Affinity-purified antibodies and cDNA probes specific for the chicken erythrocyte anion transporter (also referred to as band 3) have been used to demonstrate that this protein is expressed in a highly cell- type-specific manner in the avian kidney ...
Cox, John V., Lazarides, Elias, Moon, Randall T.   +2 more
core   +1 more source

Inhibiting ERK Activation with CI-1040 Leads to Compensatory Upregulation of Alternate MAPKs and Plasminogen Activator Inhibitor-1 following Subtotal Nephrectomy with No Impact on Kidney Fibrosis [PDF]

, 2015
Extracellular-signal regulated kinase (ERK) activation by MEK plays a key role in many of the cellular processes that underlie progressive kidney fibrosis including cell proliferation, apoptosis and transforming growth factor β1-mediated epithelial to ...
AA Eddy, Arif Khwaja, B Conway, B Hinz, C Stambe, D Bokemeyer, D Bokemeyer, D Feliers, David Long, DY Rhyu, E Diaz-Flores, Faith Hannah Nutter, FY Ma, FY Ma, FY Ma, G Wolf, GA Reif, GM D'Abaco, H Fujita, H Ha, H Tamouza, HJ Anders, J Chen, John L. Haylor, JW Pippin, JY Seo, L Aoudjit, LF Allen, LL Huang, M Peake, M Sabbatini, M Zeisberg, MA Chetram, MH De Borst, N Sakai, P Moreno-Layseca, PM Lorusso, R Ohashi, R Roskoski Jr, S Omori, S Wang, S Wang, SD Oldroyd, SK Jo, SP Davies, T Ishida, T Masaki, T Wada, T Xu, W Bechtel, Y Han   +50 more
core   +2 more sources

Danger in the jungle:sensible care to reduce avoidable acute kidney injury in hospitalized children [PDF]

, 2020
When children require hospital admission, many receive medications with nephrotoxic potential. As such, this can translate into an increased risk of acute kidney injury.
Bagshaw, Sean M., Bell, Samira, Selby, Nicholas M.   +2 more
core   +2 more sources

Dose of colistin. a work in progress? [PDF]

, 2015
We thank Rashid and colleagues [1] and Honoré and colleagues [2] for their comments regarding our article on risk factors for acute kidney injury in pa- tients receiving colistin or other nephrotoxic antimi- crobials [3].
Antonelli, M., De Pascale, G, Montini, L, Rocco, Monica   +3 more
core   +1 more source

Emphysematous Pyelonephritis in a Non-Diabetic Renal Transplant Patient: A Rare Encounter [PDF]

Translational Research in Urology
Introduction: Emphysematous pyelonephritis is a necrotizing infection characterized by the presence of gas in the renal parenchyma, collecting system, and peri-renal tissues.
Asad Bashir, Umar Farooq, Nasrum Minallah, Fiaz Touqeer, Salman Jamil, Rubab Abid   +5 more
doaj   +1 more source

Protocol and establishment of a Queensland renal biopsy registry in Australia

BMC Nephrology, 2020
Background Renal biopsy is often required to obtain information for diagnosis, management and prognosis of kidney disease that can be broadly classified into acute kidney injury (AKI) and chronic kidney disease (CKD).
Joseph Patrick Burke, Manaf Aljishi, Leo Francis, Wendy Hoy, Dakshinamurthy Divi, Roy Cherian, Jeremy Frazier, Glenda Gobe, Pedro Gois, Sridevi Govindarajulu, Sonny Huynh, Shilpanjali Jesudason, George John, Krishan Madhan, Andrew Mallett, Valli Manickam, Clyson Mutatiri, Shu-Kay Ng, Zaw Thet, Peter Trnka, Sree Krishna Venuthurupalli, Dwarakanathan Ranganathan   +21 more
doaj   +1 more source

Association of urinary uromodulin with kidney function decline and mortality: the health ABC study
. [PDF]

, 2017
BackgroundUrine uromodulin (uUMOD) is a protein secreted by the kidney tubule. Recent studies have suggested that higher uUMOD may be associated with improved kidney and mortality outcomes.MethodsUsing a case-cohort design, we evaluated the association ...
Bennett, Michael R, Devarajan, Prasad, Fried, Linda F, Garimella, Pranav S, Gutiérrez, Orlando M, Harris, Tamara B, Ix, Joachim H, Katz, Ronit, Kritchevsky, Stephen B, Parikh, Chirag R, Sarnak, Mark J, Shlipak, Michael G   +11 more
core   +1 more source

Very Early Severe Posttransplant Recurrent Antineutrophil Cytoplasmic Antibody-Associated Glomerulonephritis after Kidney Transplantation: Two Case Reports

Case Reports in Nephrology, 2022
Successful kidney transplantation (KTx) in patients with antineutrophil cytoplasmic antibody-associated vasculitis (AAV) has been reported with excellent patient and graft survival rates.
Reda Laamech, Hamza Naciri-Bennani, Diane Giovannini, Johan Noble, Bénédicte Janbon, Paolo Malvezzi, Thomas Jouve, Lionel Rostaing   +7 more
doaj   +1 more source