Results 41 to 50 of about 3,981,439 (405)

Inhibiting ERK Activation with CI-1040 Leads to Compensatory Upregulation of Alternate MAPKs and Plasminogen Activator Inhibitor-1 following Subtotal Nephrectomy with No Impact on Kidney Fibrosis [PDF]

, 2015
Extracellular-signal regulated kinase (ERK) activation by MEK plays a key role in many of the cellular processes that underlie progressive kidney fibrosis including cell proliferation, apoptosis and transforming growth factor β1-mediated epithelial to ...
AA Eddy, Arif Khwaja, B Conway, B Hinz, C Stambe, D Bokemeyer, D Bokemeyer, D Feliers, David Long, DY Rhyu, E Diaz-Flores, Faith Hannah Nutter, FY Ma, FY Ma, FY Ma, G Wolf, GA Reif, GM D'Abaco, H Fujita, H Ha, H Tamouza, HJ Anders, J Chen, John L. Haylor, JW Pippin, JY Seo, L Aoudjit, LF Allen, LL Huang, M Peake, M Sabbatini, M Zeisberg, MA Chetram, MH De Borst, N Sakai, P Moreno-Layseca, PM Lorusso, R Ohashi, R Roskoski Jr, S Omori, S Wang, S Wang, SD Oldroyd, SK Jo, SP Davies, T Ishida, T Masaki, T Wada, T Xu, W Bechtel, Y Han   +50 more
core   +2 more sources

Kidney [PDF]

American Journal of Transplantation, 2016
Kidney transplant provides significant survival, cost, and quality-of-life benefits over dialysis in patients with end-stage kidney disease, but the number of kidney transplant candidates on the waiting list continues to grow annually. By the end of 2014, nearly 100,000 adult candidates and 1500 pediatric candidates were waiting for kidney transplant ...
A, Hart, J M, Smith, M A, Skeans, S K, Gustafson, D E, Stewart, W S, Cherikh, J L, Wainright, G, Boyle, J J, Snyder, B L, Kasiske, A K, Israni   +10 more
openaire   +2 more sources

Global Epidemiology of End-Stage Kidney Disease and Disparities in Kidney Replacement Therapy

American Journal of Nephrology, 2021
Background: The global epidemiology of end-stage kidney disease (ESKD) reflects each nation’s unique genetic, environmental, lifestyle, and sociodemographic characteristics.
J. Thurlow, M. Joshi, G. Yan, K. Norris, L. Agodoa, C. Yuan, R. Nee   +6 more
semanticscholar   +1 more source

Inter-study reproducibility of arterial spin labelling magnetic resonance imaging for measurement of renal perfusion in healthy volunteers at 3 Tesla [PDF]

, 2014
Background: Measurement of renal perfusion is a crucial part of measuring kidney function. Arterial spin labelling magnetic resonance imaging (ASL MRI) is a non-invasive method of measuring renal perfusion using magnetised blood as endogenous contrast ...
Delles, C., Foster, J.E., Gillis, K.A., Jardine, A.G., Mark, P.B., McComb, C., Morris, S.T.W., Patel, R.K., Roditi, G.H., Schneider, M.P., Taylor, A.H.M.   +10 more
core   +3 more sources

Decapsulation of the Kidney [PDF]

The Boston Medical and Surgical Journal, 1904
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openaire   +3 more sources

Protocol and establishment of a Queensland renal biopsy registry in Australia

BMC Nephrology, 2020
Background Renal biopsy is often required to obtain information for diagnosis, management and prognosis of kidney disease that can be broadly classified into acute kidney injury (AKI) and chronic kidney disease (CKD).
Joseph Patrick Burke, Manaf Aljishi, Leo Francis, Wendy Hoy, Dakshinamurthy Divi, Roy Cherian, Jeremy Frazier, Glenda Gobe, Pedro Gois, Sridevi Govindarajulu, Sonny Huynh, Shilpanjali Jesudason, George John, Krishan Madhan, Andrew Mallett, Valli Manickam, Clyson Mutatiri, Shu-Kay Ng, Zaw Thet, Peter Trnka, Sree Krishna Venuthurupalli, Dwarakanathan Ranganathan   +21 more
doaj   +1 more source

Pathophysiology of COVID-19-associated acute kidney injury

Nature Reviews Nephrology, 2021
Although respiratory failure and hypoxaemia are the main manifestations of COVID-19, kidney involvement is also common. Available evidence supports a number of potential pathophysiological pathways through which acute kidney injury (AKI) can develop in ...
M. Legrand, S. Bell, L. Forni, M. Joannidis, J. Koyner, Kathleen D. Liu, V. Cantaluppi   +6 more
semanticscholar   +1 more source

Dose of colistin. a work in progress? [PDF]

, 2015
We thank Rashid and colleagues [1] and Honoré and colleagues [2] for their comments regarding our article on risk factors for acute kidney injury in pa- tients receiving colistin or other nephrotoxic antimi- crobials [3].
Antonelli, M., De Pascale, G, Montini, L, Rocco, Monica   +3 more
core   +1 more source

Risk factor mining and prediction of urine protein progression in chronic kidney disease: a machine learning- based study

BMC Medical Informatics and Decision Making, 2023
Background Chronic kidney disease (CKD) is a global public health concern. Therefore, to provide timely intervention for non-hospitalized high-risk patients and rationally allocate limited clinical resources is important to mine the key factors when ...
Yufei Lu, Yichun Ning, Yang Li, Bowen Zhu, Jian Zhang, Yan Yang, Weize Chen, Zhixin Yan, Annan Chen, Bo Shen, Yi Fang, Dong Wang, Nana Song, Xiaoqiang Ding   +13 more
doaj   +1 more source

An atlas of healthy and injured cell states and niches in the human kidney

bioRxiv, 2021
Understanding kidney disease relies on defining the complexity of cell types and states, their associated molecular profiles and interactions within tissue neighbourhoods^ 1 .
B. Lake, R. Menon, S. Winfree, Qiwen Hu, R. M. Ferreira, K. Kalhor, Daria Barwinska, E. Otto, M. Ferkowicz, D. Diep, Nongluk Plongthongkum, Amanda Knoten, Sarah Urata, A. Naik, S. Eddy, Bo Zhang, Yan Wu, Diane Salamon, James C Williams, Xin Wang, Karol S. Balderrama, P. Hoover, Evan Murray, A. Vijayan, Fei Chen, S. Waikar, S. Rosas, F. Wilson, P. Palevsky, K. Kiryluk, J. Sedor, R. Toto, C. Parikh, Eric H. Kim, Evan Z. Macosko, P. Kharchenko, J. Gaut, J. Hodgin, Michael T. Eadon, P. Dagher, T. El-Achkar, Kun Zhang, M. Kretzler, Sanjay Jain   +43 more
semanticscholar   +1 more source