Results 41 to 50 of about 921,567 (386)

A Multi-Stage Framework for the 2022 Multi-Structure Segmentation for Renal Cancer Treatment [PDF]

arXiv, 2022
Three-dimensional (3D) kidney parsing on computed tomography angiography (CTA) images is of great clinical significance. Automatic segmentation of kidney, renal tumor, renal vein and renal artery benefits a lot on surgery-based renal cancer treatment. In this paper, we propose a new nnhra-unet network, and use a multi-stage framework which is based on ...
arxiv  

Frequent Mutations of VHL Gene and the Clinical Phenotypes in the Largest Chinese Cohort With Von Hippel–Lindau Disease

Frontiers in Genetics, 2019
Von Hippel–Lindau (VHL) disease is a rare autosomal-dominant inherited tumor syndrome. We aimed to analyze the correlations between frequent VHL mutations and phenotypes in Chinese VHL families.
Baoan Hong, Baoan Hong, Baoan Hong, Baoan Hong, Baoan Hong, Baoan Hong, Kaifang Ma, Kaifang Ma, Kaifang Ma, Kaifang Ma, Jingcheng Zhou, Jingcheng Zhou, Jingcheng Zhou, Jingcheng Zhou, Jiufeng Zhang, Jiufeng Zhang, Jiufeng Zhang, Jiufeng Zhang, Jiangyi Wang, Jiangyi Wang, Jiangyi Wang, Jiangyi Wang, Shengjie Liu, Shengjie Liu, Shengjie Liu, Shengjie Liu, Zhongyuan Zhang, Zhongyuan Zhang, Zhongyuan Zhang, Zhongyuan Zhang, Lin Cai, Lin Cai, Lin Cai, Lin Cai, Ning Zhang, Ning Zhang, Kan Gong, Kan Gong, Kan Gong, Kan Gong   +39 more
doaj   +1 more source

Dual mTOR/PI3K inhibition limits PI3K-dependent pathways activated upon mTOR inhibition in autosomal dominant polycystic kidney disease [PDF]

, 2018
Autosomal dominant polycystic kidney disease (ADPKD) is characterized by the development of kidney cysts leading to kidney failure in adulthood. Inhibition of mammalian target of rapamycin (mTOR) slows polycystic kidney disease (PKD) progression in ...
Arcaro, Alexandre, Castelletti, Deborah, Fu, Xuebin, Liu, Yang, Mischak, Harald, Mullen, William, Pejchinovski, Martin, Serra, Andreas L., Siwy, Justyna, Wang, Xueqi, Watnick, Terry J.   +10 more
core   +2 more sources

Basic Research in Kidney Cancer [PDF]

European Urology, 2011
AbstractContextAdvances in basic research will enhance prognosis, diagnosis, and treatment of renal cancer patients.ObjectiveTo discuss advances in our understanding of the molecular basis of renal cancer, targeted therapies, renal cancer and immunity, and genetic factors and renal cell carcinoma (RCC).Evidence acquisitionData on recently published ...
Pouliot, Frederic, Brannon, A. Rose, Oosterwijk, Egbert, Mulders, Peter F. A., Kirkali, Ziya, Junker, Kerstin, Uemura, Hirotsugo, Belldegrun, Arie, Finley, David S., Rathmell, W. Kimryn   +9 more
openaire   +5 more sources

CYP1B1 promotes tumorigenesis via altered expression of CDC20 and DAPK1 genes in renal cell carcinoma. [PDF]

, 2015
BackgroundCytochrome P450 1B1 (CYP1B1) has been shown to be up-regulated in many types of cancer including renal cell carcinoma (RCC). Several reports have shown that CYP1B1 can influence the regulation of tumor development; however, its role in RCC has ...
Arichi, Naoko, Chang, Inik, Dahiya, Rajvir, Deng, Guoren, Fukuhara, Shinichiro, Hiraki, Miho, Hirata, Hiroshi, Majid, Shahana, Mitsui, Yozo, Shahryari, Varahram, Shiina, Hiroaki, Tanaka, Yuichiro, Wong, Darryn K, Yamamura, Soichiro, Yasumoto, Hiroaki   +14 more
core   +2 more sources

Automated Small Kidney Cancer Detection in Non-Contrast Computed Tomography [PDF]

arXiv, 2023
This study introduces an automated pipeline for renal cancer (RC) detection in non-contrast computed tomography (NCCT). In the development of our pipeline, we test three detections models: a shape model, a 2D-, and a 3D axial-sample model. Training (n=1348) and testing (n=64) data were gathered from open sources (KiTS23, Abdomen1k, CT-ORG) and ...
arxiv  

Nonlinear 3-D simulation of high-intensity focused ultrasound therapy in the kidney [PDF]

38th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC), 2016, pp. 5648-5651, 2016
Kidney cancer is a severe disease which can be treated non-invasively using high-intensity focused ultrasound (HIFU) therapy. However, tissue in front of the transducer and the deep location of kidney can cause significant losses to the efficiency of the treatment.
arxiv   +1 more source

Efficacy and safety of Androgen Deprivation Therapy (ADT) combined with modified docetaxel chemotherapy versus ADT combined with standard docetaxel chemotherapy in patients with metastatic castration-resistant prostate cancer: study protocol for a multicentre prospective randomized controlled trial

BMC Cancer, 2022
Background Androgen deprivation therapy (ADT) combined with docetaxel chemotherapy is the standard treatment for metastatic castration-resistant prostate cancer (mCRPC) patients.
Xiangwei Yang, Hong Chen, Duanya Xu, Xianju Chen, Yamei Li, Jun Tian, Dongwen Wang, Jun Pang   +7 more
doaj   +1 more source

Urine Single-Cell RNA Sequencing in Focal Segmental Glomerulosclerosis Reveals Inflammatory Signatures

Kidney International Reports, 2022
Introduction: Individuals with focal segmental glomerular sclerosis (FSGS) typically undergo kidney biopsy only once, which limits the ability to characterize kidney cell gene expression over time.
Khun Zaw Latt, Jurgen Heymann, Joseph H. Jessee, Avi Z. Rosenberg, Celine C. Berthier, Arnon Arazi, Sean Eddy, Teruhiko Yoshida, Yongmei Zhao, Vicky Chen, George W. Nelson, Margaret Cam, Parimal Kumar, Monika Mehta, Michael C. Kelly, Matthias Kretzler, Patricio E. Ray, Marva Moxey-Mims, Gregory H. Gorman, Brent L. Lechner, Renu Regunathan-Shenk, Dominic S. Raj, Katalin Susztak, Cheryl A. Winkler, Jeffrey B. Kopp   +24 more
doaj  

Neuropeptide G Protein-Coupled Receptors as Oncotargets

Frontiers in Endocrinology, 2018
Neuropeptide G protein-coupled receptors (GPCRs) are overexpressed on numerous cancer cells. In a number of tumors, such as small cell lung cancer (SCLC), bombesin (BB) like peptides and neurotensin (NTS) function as autocrine growth factors whereby they
Terry W. Moody, Irene Ramos-Alvarez, Robert T. Jensen   +2 more
doaj   +1 more source