Results 121 to 130 of about 1,749,999 (379)

Stage-specific action of matrix metalloproteinases influences progressive hereditary kidney disease. [PDF]

open access: yes, 2006
BackgroundGlomerular basement membrane (GBM), a key component of the blood-filtration apparatus in the in the kidney, is formed through assembly of type IV collagen with laminins, nidogen, and sulfated proteoglycans.
Cosgrove, Dominic   +8 more
core   +3 more sources

RIPK3 and kidney disease

open access: yesNefrología
Receptor interacting protein kinase 3 (RIPK3) is an intracellular kinase at the crossroads of cell death and inflammation. RIPK3 contains a RIP homotypic interaction motif (RHIM) domain which allows interactions with other RHIM-containing proteins and a kinase domain that allows phosphorylation of target proteins.
Guerrero Mauvecin, Juan   +4 more
openaire   +5 more sources

Genetics of kidney disease [PDF]

open access: yesKidney International, 2003
Multiple lines of evidence suggest that susceptibility to develop end-stage renal disease (ESRD) has a significant genetic component. These studies include familial aggregation studies, comparisons of incidence rates between different racial or ethnic populations, and segregation analysis. Multiple approaches have been employed in an effort to identify
openaire   +3 more sources

Co‐expression of HSV‐1 ICP34.5 enhances the expression of gene delivered by self‐amplifying RNA and mitigates its immunogenicity

open access: yesFEBS Open Bio, EarlyView.
ICP34.5 is one of the most important antihost response proteins. The saRNA‐encoding HSV‐1 neurovirulence protein ICP34.5 clearly mediated the eukaryotic initiation factor 2 alpha subunit (eIF2α) dephosphorylation and significant suppression of innate immune responses in vitro, leading to enhanced expression of the saRNA‐encoded gene.
Xuemin Lu   +6 more
wiley   +1 more source

Geriatric Assessment in Advanced Kidney Disease [PDF]

open access: yes, 2019
Peer ...
Brown, Edwina Anne, Farrington, Ken
core   +1 more source

Semi-Automatic Segmentation of Autosomal Dominant Polycystic Kidneys using Random Forests [PDF]

open access: yesarXiv, 2015
This paper presents a method for 3D segmentation of kidneys from patients with autosomal dominant polycystic kidney disease (ADPKD) and severe renal insufficiency, using computed tomography (CT) data. ADPKD severely alters the shape of the kidneys due to non-uniform formation of cysts.
arxiv  

Association of urinary uromodulin with kidney function decline and mortality: the health ABC study
. [PDF]

open access: yes, 2017
BackgroundUrine uromodulin (uUMOD) is a protein secreted by the kidney tubule. Recent studies have suggested that higher uUMOD may be associated with improved kidney and mortality outcomes.MethodsUsing a case-cohort design, we evaluated the association ...
Bennett, Michael R   +11 more
core   +1 more source

Kidney disease in cardiology [PDF]

open access: yesNephrology Dialysis Transplantation, 2006
Topics covered in this review include the relation of estimated glomerular filtration rate, proteinuria and outcome; sudden cardiac death; contrast-induced acute kidney injury (CI-AKI); imaging; clinical trials targeting cardiovascular disease in chronic kidney disease (CKD) patients; and treatment of ischemic heart disease and valvular disease ...
openaire   +13 more sources

Patients with transobturator tape: a retrospective observational study of ten-year follow-up

open access: yesUrogynaecologia International Journal
Stress urinary incontinence (SUI) may result from intrinsic sphincter weakness or urethral hypermobility brought on by weakened muscles in the pelvic floor that sustain the urethra and bladder.
Vineet Mishra   +3 more
doaj   +1 more source

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