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Erratum: Evans M, Grams ME, Sang Y, et al., for the Chronic Kidney Disease Prognosis Consortium. Risk factors for prognosis in patients with severely decreased GFR. Kidney Int Rep. 2018;3:625-637. [PDF]

, 2018
[This corrects the article DOI: 10.1016/j.ekir.2018.01.002.]
Chronic Kidney Disease Prognosis Consortium
core   +1 more source

Association between urinary sodium, creatinine, albumin, and long term survival in chronic kidney disease [PDF]

, 2014
Dietary sodium intake is associated with hypertension and cardiovascular risk in the general population. In patients with chronic kidney disease, sodium intake has been associated with progressive renal disease, but not independently of proteinuria.
Fox, Jonathan G., Freel, E. Marie, Jardine, Alan G., Mark, Patrick, McQuarrie, Emily P., Taylor, Alison H., Traynor, Jamie P.   +6 more
core   +1 more source

Ferroptosis and kidney disease

Nefrología (English Edition), 2020
Cell death is a finely regulated process occurring through different pathways. Regulated cell death, either through apoptosis or regulated necrosis offers the possibility of therapeutic intervention. Necroptosis and ferroptosis are among the best studied forms of regulated necrosis in the context of kidney disease.
Alberto Ortiz, Julio M. Martinez-Moreno, Miguel Fontecha-Barriuso, Ana Belen Sanz, Diego Martin-Sanchez, Melania Guerrero-Hue, Maria Dolores Sanchez-Niño, Juan Antonio Moreno, Adrian M. Ramos   +8 more
openaire   +4 more sources

Myeloperoxidase in kidney disease [PDF]

Kidney International, 2003
In glomerular and tubulointerstitial disease, polymorphonuclear- and monocyte-derived reactive oxygen species may contribute to oxidative modification of proteins, lipids, and nucleic acids. In part, the processes instigated by reactive oxygen species parallel events that lead to the development of atherosclerosis. Myeloperoxidase (MPO), a heme protein
Ernst Malle, Thomas Buch, Thomas Buch, Hermann Josef Grone, Hermann Josef Grone   +4 more
openaire   +2 more sources

Modifications in FLAP's second cytosolic loop influence 5‐LOX interaction, inhibitor binding, and leukotriene formation

FEBS Letters, EarlyView.
The enzyme 5‐lipoxygenase (5‐LOX) catalyzes the first step in the biosynthesis of leukotrienes (LTs) involved in inflammatory pathophysiology. After cellular stimulation, 5‐LOX translocates to the nucleus, interacting with the 5‐LOX‐activating protein (FLAP) to form LTA4 from arachidonic acid (AA).
Erik Romp, Katharina Rataj, Stefanie König, Marcia E. Newcomer, Oliver Werz, Ulrike Garscha   +5 more
wiley   +1 more source

Acquired aplastic anemia complicated with anti-glomerular basement membrane disease successfully treated with immunosuppressive therapy: a case report

BMC Nephrology, 2022
Background Aplastic anemia (AA) is a rare but fatal disorder characterized by pancytopenia due to bone marrow hypoplasia. Anti-glomerular basement membrane disease (anti-GBM disease) is an immune complex small-vessel vasculitis that presents as rapidly ...
Kenji Matsui, Wataru Kamata, Yasuhiro Mochida, Kunihiro Ishioka, Hidekazu Moriya, Sumi Hidaka, Takayasu Ohtake, Yotaro Tamai, Shuzo Kobayashi   +8 more
doaj   +1 more source

The risk factors and predictive model for cardiac valve calcification in patients on maintenance peritoneal dialysis: a single-center retrospective study

Renal Failure, 2023
Background Cardiovascular calcification includes cardiac valve calcification (CVC) and vascular calcification. We aimed to analyze risk factors for CVC, and construct a predictive model in maintenance peritoneal dialysis (MPD) patients.Methods We ...
Yuxi Wang, Quanquan Shen, Junni Wang, Shilong Xiang, Yaomin Wang, Xiaohui Zhang, Jianghua Chen, Fei Han   +7 more
doaj   +1 more source

Identification, Characterization, and Localization of a Novel Kidney Polycystin-1-Polycystin-2 Complex [PDF]

, 2002
The functions of the two proteins defective in autosomal dominant polycystic kidney disease, polycystin-1 and polycystin-2, have not been fully clarified, but it has been hypothesized that they may heterodimerize to form a "polycystin complex" involved ...
Ackermann, Bergsma, Boletta, Cai, Charron, Chen, Foggensteiner, Gallagher, Gonzalez-Perrett, Green, Grupp, Hanaoka, Huan, Hughes, Ibraghimov Beskrovnaya, Ibraghimov Beskrovnaya, Jat, Jat, Lehtonen, Lohning, Lu, Man, Markowitz, Mochizuki, Moy, Nathke, Obermuller, Olmsted, Ong, Ong, Ong, Ong, Pollack, Pritchard, Putney, Qian, Rothman, Scheffers, Tsiokas, Vassilev, Ward, Watnick, Wu, Xu   +43 more
core   +1 more source

Circulating histones as clinical biomarkers in critically ill conditions

FEBS Letters, EarlyView.
Circulating histones are emerging as promising biomarkers in critical illness due to their diagnostic, prognostic, and therapeutic potential. Detection methods such as ELISA and mass spectrometry provide reliable approaches for quantifying histone levels in plasma samples.
José Luis García‐Gimenez, Juan Carlos Ruiz‐Rodríguez, Ricard Ferrer, Raquel Durá, Antonio Artigas, Iván Bajaña, David Bolado López de Andujar, Irene Cánovas‐Cervera, Adrián Ceccato, Luis Chiscano‐Camón, Elena Climent‐Martinez, Georgia García Fernández, Gemma Goma, Verónica Monforte, Beatriz Quevedo‐Sánchez, Adolf Ruiz‐Sanmartín, Antonio Sierra‐Rivera, Nieves Carbonell Monleón   +17 more
wiley   +1 more source

Is “chronic kidney disease” a disease? [PDF]

Journal of Evaluation in Clinical Practice, 2018
AbstractSeveral philosophers of medicine have attempted to answer the question “what is disease?” In current clinical practice, an umbrella term “chronic kidney disease” (CKD) encompasses a wide range of kidney health states from commonly prevalent subclinical, asymptomatic disease to rare end‐stage renal disease requiring transplant or dialysis to ...
Smart, B, Stevens, R, Verbakel, J
openaire   +4 more sources