Results 1 to 10 of about 1,033,542 (310)

miRNAs in stem cell-derived extracellular vesicles for acute kidney injury treatment: comprehensive review of preclinical studies

Stem Cell Research & Therapy, 2019
Stem cell therapy has been applied in many fields. Basic and clinical studies on stem cell therapy for acute kidney injury (AKI) have been conducted. Stem cells have been found to exert renal protection through a variety of mechanisms, such as regulating
Si-Yang Wang, Quan Hong, Chao-Yang Zhang, Yuan-Jun Yang, Guang-Yan Cai, Xiang-Mei Chen   +5 more
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COMPARISON OF SUCCESSFUL OUTCOME OF FLAP VERSUS NO-FLAP IN O’CONOR & SOKOL TECHNIQUE FOR VESICOVAGINAL FISTULA REPAIR

Khyber Medical University Journal, 2020
OBJECTIVE: To compare the successful outcome of flap versus no-flap in O’Conor & Sokol technique for simple vesicovaginal fistula (VVF) repair. METHODS: This quasi-experimental study was conducted in department of Urology, Institute of Kidney Diseases,
Liaqat Ali, Faiza Hayat, Saifullah Khan, Sikander Hayat, Kifayat Tariq, Asiya Hassan   +5 more
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The PI3K-Akt-mTOR pathway mediates renal pericyte-myofibroblast transition by enhancing glycolysis through HKII

Journal of Translational Medicine, 2023
Background Pericyte-myofibroblast transition (PMT) has been confirmed to contribute to renal fibrosis in several kidney diseases, and transforming growth factor-β1 (TGF-β1) is a well-known cytokine that drives PMT.
Liangmei Chen, Xiaofan Li, Yiyao Deng, Jianwen Chen, Mengjie Huang, Fengge Zhu, Zhumei Gao, Lingling Wu, Quan Hong, Zhe Feng, Guangyan Cai, Xuefeng Sun, Xueyuan Bai, Xiangmei Chen   +13 more
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Insulin-Like Growth Factor Binding Proteins in Kidney Disease

Frontiers in Pharmacology, 2021
The seven members of the insulin-like growth factor (IGF) binding protein family (IGFBPs) were initially considered to be the regulatory proteins of IGFs in the blood circulation, mainly as the subsequent reserve for bidirectional regulation of IGF ...
Shuqiang Wang, Shuqiang Wang, Kun Chi, Di Wu, Quan Hong   +4 more
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Progress of small ubiquitin-related modifiers in kidney diseases

Chinese Medical Journal, 2019
. Objective:. Small ubiquitin-related modifiers (SUMOs) are a group of post-translational modification proteins extensively expressed in eukaryotes. Abnormal SUMOylation can lead to the development of various diseases.
Ou Li, Qian Ma, Fei Li, Guang-Yan Cai, Xiang-Mei Chen, Quan Hong, Li-Min Chen   +6 more
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Macrophage polarization in innate immune responses contributing to pathogenesis of chronic kidney disease

BMC Nephrology, 2020
Chronic kidney disease (CKD) is characterized by inflammation, injury and fibrosis. Dysregulated innate immune responses mediated by macrophages play critical roles in progressive renal injury. The differentiation and polarization of macrophages into pro-
Hewang Lee, Michael B. Fessler, Peng Qu, Jurgen Heymann, Jeffrey B. Kopp   +4 more
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FACTORS INFLUENCING RECOVERY TIME AND HOSPITAL STAY AFTER TRANSURETHRAL RESECTION OF PROSTATE (TURP)

Journal of Gandhara Medical and Dental Sciences
OBJECTIVES This study aimed to evaluate the factors influencing recovery time and the length of hospital stay (LHS) following TURP surgery. METHODOLOGY A descriptive study was conducted over 6 months in the Department of Urology at the Institute of
Allah Yar khan, Muhammad Izhar, waqas ahmad, muhammad kamran khan, tariq saleem khan   +4 more
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Clinical features of acute kidney injury in patients with nephrotic syndrome and minimal change disease: a retrospective, cross-sectional study

Chinese Medical Journal, 2021
. Background:. Minimal change nephropathy (MCD) is a common pathological type of nephrotic syndrome and is often associated with acute kidney injury (AKI).
Shu-Peng Lin, Feng-Ge Zhu, Jin-Ling Meng, Xiao-Wei Sun, Jing Cui, Shuang Liang, Zhong Yin, Xue-Feng Sun, Guang-Yan Cai, Pei-Fang Wei   +9 more
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Regulation of connective tissue growth factor expression by miR-133b for the treatment of renal interstitial fibrosis in aged mice with unilateral ureteral obstruction

Stem Cell Research & Therapy, 2021
Introduction Renal interstitial fibrosis, an important pathological feature of kidney aging and chronic renal failure, is regulated by mesenchymal stem cells (MSCs).
Dan Cao, Yuan Wang, Yingjie Zhang, Yinping Zhang, Qi Huang, Zhong Yin, Guangyan Cai, Xiangmei Chen, Xuefeng Sun   +8 more
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MSCs-derived HGF alleviates senescence after AKI by modulating mitoSTAT3-controlled copper flux and respiration

Stem Cell Research & Therapy
Background Human umbilical cord-derived mesenchymal stem cells (hUC-MSCs) can reverse senescence after acute kidney injury (AKI) via maintaining mitochondrial homeostasis.
Kaiting Zhuang, Wenjuan Wang, Cheng Xu, Siyang Wang, Yuhao Chen, Yingjie Zhang, Yanjun Liang, Xumin Zheng, Xiangmei Chen, Zhe Feng, Guangyan Cai   +10 more
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