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Porphyria and kidney diseases [PDF]
Clinical Kidney Journal, 2018 The kidneys, after the bone marrow and liver, are third in terms of the amounts of haem synthesized daily. Haem is incorporated into haemoproteins that are critical to renal physiology.
N. Pallet +5 more
semanticscholar +6 more sources
Gut Dysbiosis and Kidney Diseases
Frontiers in Medicine, 2022 Gut dysbiosis is defined as disorders of gut microbiota and loss of barrier integrity, which are ubiquitous on pathological conditions and associated with the development of various diseases.
C. Cao, Han Zhu, Ying Yao, R. Zeng
semanticscholar +1 more source
Mitochondrial Redox Signaling and Oxidative Stress in Kidney Diseases
Biomolecules, 2021 Mitochondria are essential organelles in physiology and kidney diseases, because they produce cellular energy required to perform their function. During mitochondrial metabolism, reactive oxygen species (ROS) are produced.
Ana Karina Aranda-Rivera +3 more
semanticscholar +1 more source
The Cross-Link between Ferroptosis and Kidney Diseases
Oxidative Medicine and Cellular Longevity, 2021 Acute and chronic kidney injuries result from structural dysfunction and metabolic disorders of the kidney in various etiologies, which significantly affect human survival and social wealth.
Jingyu Wang, Yi Liu, Yaqing Wang, Li Sun
semanticscholar +1 more source
Immunological Reviews, 2022 SummaryDysregulation and accelerated activation of the alternative pathway (AP) of complement is known to cause or accentuate several pathologic conditions in which kidney injury leads to the appearance of hematuria and proteinuria and ultimately to the development of chronic renal failure.
Erica Daina +2 more
openaire +2 more sources
Pyroptosis: A New Frontier in Kidney Diseases
Oxidative Medicine and Cellular Longevity, 2021 Pyroptosis is a pattern of programmed cell death that significantly differs from apoptosis and autophagy in terms of cell morphology and function. The process of pyroptosis is characterized predominantly by the formation of gasdermin protein family ...
Ke-jia Zhang +8 more
semanticscholar +1 more source
Estrogen and estrogen receptors in kidney diseases
Renal Failure, 2021 Acute kidney injury (AKI) and chronic kidney disease (CKD) are posing great threats to global health within this century. Studies have suggested that estrogen and estrogen receptors (ERs) play important roles in many physiological processes in the kidney.
Hao-Yang Ma, Shuang Chen, Yang Du
semanticscholar +1 more source
Postbiotics and Kidney Disease
Toxins, 2022 Chronic kidney disease (CKD) is projected to become the fifth global cause of death by 2040 as a result of key shortcomings in the current methods available to diagnose and treat kidney diseases. In this regard, the novel holobiont concept, used to describe an individual host and its microbial community, may pave the way towards a better understanding ...
Chiara Favero +5 more
openaire +5 more sources
Defective Mitochondrial Fatty Acid Oxidation and Lipotoxicity in Kidney Diseases
Frontiers in Medicine, 2020 The kidney is a highly metabolic organ and uses high levels of ATP to maintain electrolyte and acid-base homeostasis and reabsorb nutrients. Energy depletion is a critical factor in development and progression of various kidney diseases including acute ...
Hee-Seong Jang +3 more
semanticscholar +1 more source