Results 1 to 10 of about 871,693 (313)

miRNAs in stem cell-derived extracellular vesicles for acute kidney injury treatment: comprehensive review of preclinical studies

open access: yesStem Cell Research & Therapy, 2019
Stem cell therapy has been applied in many fields. Basic and clinical studies on stem cell therapy for acute kidney injury (AKI) have been conducted. Stem cells have been found to exert renal protection through a variety of mechanisms, such as regulating
Si-Yang Wang   +5 more
doaj   +1 more source

COMPARISON OF SUCCESSFUL OUTCOME OF FLAP VERSUS NO-FLAP IN O’CONOR & SOKOL TECHNIQUE FOR VESICOVAGINAL FISTULA REPAIR

open access: yesKhyber Medical University Journal, 2020
OBJECTIVE: To compare the successful outcome of flap versus no-flap in O’Conor & Sokol technique for simple vesicovaginal fistula (VVF) repair. METHODS: This quasi-experimental study was conducted in department of Urology, Institute of Kidney Diseases,
Liaqat Ali   +5 more
doaj   +1 more source

Insulin-Like Growth Factor Binding Proteins in Kidney Disease

open access: yesFrontiers in Pharmacology, 2021
The seven members of the insulin-like growth factor (IGF) binding protein family (IGFBPs) were initially considered to be the regulatory proteins of IGFs in the blood circulation, mainly as the subsequent reserve for bidirectional regulation of IGF ...
Shuqiang Wang   +4 more
doaj   +1 more source

Progress of small ubiquitin-related modifiers in kidney diseases

open access: yesChinese Medical Journal, 2019
. Objective:. Small ubiquitin-related modifiers (SUMOs) are a group of post-translational modification proteins extensively expressed in eukaryotes. Abnormal SUMOylation can lead to the development of various diseases.
Ou Li   +6 more
doaj   +1 more source

Macrophage polarization in innate immune responses contributing to pathogenesis of chronic kidney disease

open access: yesBMC Nephrology, 2020
Chronic kidney disease (CKD) is characterized by inflammation, injury and fibrosis. Dysregulated innate immune responses mediated by macrophages play critical roles in progressive renal injury. The differentiation and polarization of macrophages into pro-
Hewang Lee   +4 more
doaj   +1 more source

The PI3K-Akt-mTOR pathway mediates renal pericyte-myofibroblast transition by enhancing glycolysis through HKII

open access: yesJournal of Translational Medicine, 2023
Background Pericyte-myofibroblast transition (PMT) has been confirmed to contribute to renal fibrosis in several kidney diseases, and transforming growth factor-β1 (TGF-β1) is a well-known cytokine that drives PMT.
Liangmei Chen   +13 more
doaj   +1 more source

Severity of Acute Kidney Injury and its Effect on Outcome in Patients of Dengue Virus Infection

open access: yesPakistan Journal of Medical Research, 2021
Background: Dengue fever is a mosquito borne viral illness that has endangered a vast population of tropical and sub-tropical areas. Dengue has multi-system involvement including liver, hematological, respiratory and central nervous systems. Spectrum of
Muhammad Tanzeel Abbasi   +5 more
doaj   +2 more sources

Clinical features of acute kidney injury in patients with nephrotic syndrome and minimal change disease: a retrospective, cross-sectional study

open access: yesChinese Medical Journal, 2021
. Background:. Minimal change nephropathy (MCD) is a common pathological type of nephrotic syndrome and is often associated with acute kidney injury (AKI).
Shu-Peng Lin   +9 more
doaj   +1 more source

Regulation of connective tissue growth factor expression by miR-133b for the treatment of renal interstitial fibrosis in aged mice with unilateral ureteral obstruction

open access: yesStem Cell Research & Therapy, 2021
Introduction Renal interstitial fibrosis, an important pathological feature of kidney aging and chronic renal failure, is regulated by mesenchymal stem cells (MSCs).
Dan Cao   +8 more
doaj   +1 more source

Better pulmonary function is associated with greater handgrip strength in a healthy Chinese Han population

open access: yesBMC Pulmonary Medicine, 2020
Background Handgrip strength (HGS) has been widely studied in clinical and epidemiological settings, but the relationship between HGS and pulmonary function is still controversial.
Liangmei Chen   +17 more
doaj   +1 more source

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