Results 21 to 30 of about 552,750 (375)

The critical role of the Hippo signaling pathway in kidney diseases

Frontiers in Pharmacology, 2022
The Hippo signaling pathway is involved in cell growth, proliferation, and apoptosis, and it plays a key role in regulating organ size, tissue regeneration, and tumor development.
Yuting Sun, De Jin, Ziwei Zhang, Di Jin, JiaoJiao Xue, LiYun Duan, YuQing Zhang, XiaoMin Kang, FengMei Lian, FengMei Lian   +9 more
doaj   +1 more source

Rare Combination of Phenotypes of Karyomegalic Interstitial Nephritis and Autosomal Recessive Polycystic Kidney Disease in an Omani Child. [PDF]

Oman Med J
Autosomal recessive polycystic kidney disease is one of the most prevalent inherited cystic kidney diseases in infants and children, common in highly consanguineous societies such as Oman. Karyomegalic interstitial nephritis is a rare cause of hereditary
Al Alawi I, Al Shehhi M, Al Riyami MS, Al Kalbani N, Al Hosni A, Al Mimani A, Al Salmi I, Sayer JA.   +7 more
europepmc   +2 more sources

Results of targeted next-generation sequencing in children with cystic kidney diseases often change the clinical diagnosis.

PLoS ONE, 2020
Cystic kidney diseases are a very heterogeneous group of chronic kidney diseases. The diagnosis is usually based on clinical and ultrasound characteristics and the final diagnosis is often difficult to be made.
Lena Obeidova, Tomas Seeman, Filip Fencl, Kveta Blahova, Jan Hojny, Veronika Elisakova, Jana Reiterova, Jitka Stekrova   +7 more
doaj   +1 more source

Imaging of Kidney Cysts and Cystic Kidney Diseases in Children: An International Working Group Consensus Statement.

Radiology, 2019
Kidney cysts can manifest as focal disease (simple and complex kidney cysts), affect a whole kidney (eg, multicystic dysplastic kidney or cystic dysplasia), or manifest as bilateral cystic disease (eg, autosomal recessive polycystic kidney disease [ARPKD]
C. Gimpel, E. Fred Avni, L. Breysem, K. Burgmaier, A. Caroli, M. Cetiner, D. Haffner, Erum A. Hartung, D. Franke, J. König, M. Liebau, D. Mekahli, Albert C. M. Ong, L. Pape, A. Titieni, R. Torra, P. Winyard, F. Schaefer   +17 more
semanticscholar   +1 more source

Approach to Inherited Cystic Kidney Disease

Güncel Pediatri, 2015
Cystic kidney diseases are the most frequent form of inherited kidney diseases which have different etiology, pathogenesis, clinical presentation and prognosis. Although diagnosis based on, family history, clinical presentation and imaging modalities, in
Aysel Taktak, Nilgün Çakar
doaj   +1 more source

Fetal polycystic kidney disease: Pathological overview

Journal of the Scientific Society, 2013
Polycystic kidney disease is a rare developmental anomaly inherited as autosomal dominant or autosomal recessive. It is characterized by cystic dilatation of the collecting ducts frequently associated with hepatic involvement and progression to renal ...
Sunita B Patil, Madhura D Paricharak, Deepak G Paricharak, S S More   +3 more
doaj   +1 more source

Primary retroperitoneal mucinous cystic tumour of borderline malignancy mimicking kidney duplicate: cases report and literature review

BMC Urology, 2023
Background Primary retroperitoneal mucinous cystic tumours with borderline malignancy (PRMC-BM) are rare and difficult to diagnose preoperatively. We are the first to report two cases of PRMC-BM which mimic a duplex kidney and evaluate the outcomes of ...
Junlong Zhang, Qinsong Zeng, Jihui Kang, Junxing Chen, Guiyuan Luo, Yueyou Liang   +5 more
doaj   +1 more source

Embracing Sex-specific Differences in Engineered Kidney Models for Enhanced Biological Understanding [PDF]

, 2023
In vitro models play a crucial role in advancing our understanding of biological processes, disease mechanisms, and developing screening platforms for drug discovery. Kidneys play an instrumental role in transport and elimination of drugs and toxins.
arxiv   +1 more source

Wall Tension and Tubular Resistance in Kidney Cystic Conditions

Biomedicines, 2023
The progressive formation of single or multiple cysts accompanies several renal diseases. Specifically, (i) genetic forms, such as adult dominant polycystic kidney disease (ADPKD), and (ii) acquired cystic kidney disease (ACKD) are probably the most ...
Michele Della Corte, Davide Viggiano
doaj   +1 more source

Ciliopathies - from rare inherited cystic kidney diseases to basic cellular function

Molecular and Cellular Pediatrics, 2015
BackgroundPrimary cilia are membrane-bound microtubule-based protuberances of the cell membrane projecting to the extracellular environment. While little attention was paid to this subcellular structure over a long time, recent research has highlighted ...
S. Habbig, M. Liebau
semanticscholar   +1 more source