Results 111 to 120 of about 857,514 (313)
South African Medical Journal, 2015 It is known that, for many reasons, general practitioners(GPs) find renal disease difficult to diagnose, understandand treat. The terms chronic kidney disease (CKD) andglomerular filtration rate (GFR), representing the renalfunction equation, have been introduced to clarify someof these difficulties.
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Advanced Functional Materials, EarlyView.The MPTT‐nanozyme‐hydrogel system (Mn3O4@ChS‐HA) provides a multifunctional therapeutic strategy for intervertebral disc degeneration (IVDD), effectively targeting oxidative stress and enhancing AF repair by restoring extracellular matrix (ECM) and redox homeostasis.
Yangyang Chen +13 more
wiley +1 more source
THE FUNCTION OF THE KIDNEYS IN PATIENTS SUFFERING FROM CHRONIC CARDIAC DISEASE WITHOUT SIGNS OF HEART FAILURE [PDF]
, 1928 Harold J. Stewart, John F. McIntosh
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H2O2‐Generating Advanced Nanomaterials for Cancer Treatment
Advanced Functional Materials, EarlyView.H2O2‐generating nanoplatforms can exploit tumor redox imbalance for O2 and toxic reactive oxygen species generation, leading to hypoxia reversal, and apoptosis of cancer cells, respectively. This review highlights the mechanisms of these nanoplatforms, including exogenous H₂O₂ delivery, endogenous amplification, and metal peroxides, which leads to ...
Kiyan Musaie +8 more
wiley +1 more source
Diseases of the Genito-Urinary Organs and the Kidney. [PDF]
, 1913 Robert Holmes Greene, Harlow Brooks
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Advanced Functional Materials, EarlyView.Oct4‐nanoscript, a biomimetic nanoparticle‐based artificial transcription factor, precisely regulates cellular rejuvenation by activating Oct4 target genes, restoring epigenetic marks, and reducing DNA damage. In a progeria model, it effectively rescued aging‐associated pathologies and extended lifespan.
Hongwon Kim +8 more
wiley +1 more source
Cell Communication and SignalingA promising new therapy option for acute kidney injury (AKI) is mesenchymal stem cells (MSCs). However, there are several limitations to the use of MSCs, such as low rates of survival, limited homing capacity, and unclear differentiation.
Yifan Zhang +10 more
doaj +1 more source
Intraoral Drug Delivery: Bridging the Gap Between Academic Research and Industrial Innovations
Advanced Functional Materials, EarlyView.Intraoral drug delivery offers a promising route for systemic and localized therapies, yet challenges such as enzymatic degradation, limited permeability, and microbial interactions hinder efficacy. This figure highlights innovative strategies—mucoadhesive materials, enzyme inhibitors, and permeation enhancers—to overcome these barriers.
Soheil Haddadzadegan +4 more
wiley +1 more source
Oleanolic acid and its analogues: promising therapeutics for kidney disease
Chinese MedicineKidney diseases pose a significant threat to human health due to their high prevalence and mortality rates. Worryingly, the clinical use of drugs for kidney diseases is associated with more side effects, so more effective and safer treatments are ...
Dan Pan +6 more
doaj +1 more source