Results 31 to 40 of about 1,494,310 (357)

Deprivation and kidney disease – a predictor of poor outcomes [PDF]

, 2019
There is a growing body of evidence for the role of deprivation in a broad spectrum of diseases including renal disease. Deprivation has been demonstrated to be associated with poorer outcomes across a range of renal diseases including acute kidney ...
Bell, Samira, Guthrie, Greg D.
core   +2 more sources

Regulation of connective tissue growth factor expression by miR-133b for the treatment of renal interstitial fibrosis in aged mice with unilateral ureteral obstruction

Stem Cell Research & Therapy, 2021
Introduction Renal interstitial fibrosis, an important pathological feature of kidney aging and chronic renal failure, is regulated by mesenchymal stem cells (MSCs).
Dan Cao, Yuan Wang, Yingjie Zhang, Yinping Zhang, Qi Huang, Zhong Yin, Guangyan Cai, Xiangmei Chen, Xuefeng Sun   +8 more
doaj   +1 more source

Targeting kidney mesangium by nanoparticles of defined size [PDF]

, 2011
Nanoparticles are being investigated for numerous medical applications and are showing potential as an emerging class of carriers for drug delivery. Investigations on how the physicochemical properties (e.g., size, surface charge, shape, and density of ...
C. H. J. Choi, Chen, Choi, Davis, Davis, J. E. Zuckerman, Kanwar, Lahdenkari, Luft, M. E. Davis, Nurkiewicz, Ogawa, P. Webster, Peer, Ruckerl, Schipper, Schreiner, Soo Choi, Tan, Zimmermann   +19 more
core   +2 more sources

Better pulmonary function is associated with greater handgrip strength in a healthy Chinese Han population

BMC Pulmonary Medicine, 2020
Background Handgrip strength (HGS) has been widely studied in clinical and epidemiological settings, but the relationship between HGS and pulmonary function is still controversial.
Liangmei Chen, Xiaomin Liu, Qian Wang, Linpei Jia, Kangkang Song, Sasa Nie, Yinping Zhang, Dan Cao, Delong Zhao, Zuoxiang Li, Zheyi Dong, Ying Zheng, Shuwei Duan, Xuefeng Sun, Zhe Feng, Guangyan Cai, Weiguang Zhang, Xiangmei Chen   +17 more
doaj   +1 more source

Novel Omega-3 Fatty Acid Epoxygenase Metabolite Reduces Kidney Fibrosis. [PDF]

, 2016
Cytochrome P450 (CYP) monooxygenases epoxidize the omega-3 polyunsaturated fatty acid (PUFA) docosahexaenoic acid into novel epoxydocosapentaenoic acids (EDPs) that have multiple biological actions.
Hammock, Bruce D, Hye Khan, Md Abdul, Imig, John D, Lee, Kin Sing Stephen, Levick, Scott P, Sharma, Amit   +5 more
core   +3 more sources

Chronic kidney disease [PDF]

Nature Reviews Disease Primers, 2017
Chronic kidney disease (CKD) is defined by persistent urine abnormalities, structural abnormalities or impaired excretory renal function suggestive of a loss of functional nephrons. The majority of patients with CKD are at risk of accelerated cardiovascular disease and death.
Romagnani, Paola, Remuzzi, Giuseppe, Glassock, Richard, Levin, Adeera, Jager, Kitty J., Tonelli, Marcello, Massy, Ziad, Wanner, Christoph, Anders, Hans-Joachim   +8 more
openaire   +2 more sources

Association between sarcopenia and frailty in elderly patients with chronic kidney disease

Journal of Cachexia, Sarcopenia and Muscle, 2023
Background Frailty and sarcopenia are prevalent in chronic kidney disease (CKD) populations and could increase the risk for adverse health outcomes.
Che Wang, Xinru Guo, Xieguanxuan Xu, Shuang Liang, Wenling Wang, Fanglei Zhu, Siyang Wang, Jie Wu, Li Zhang, Xuefeng Sun, Xiangmei Chen, Guangyan Cai, The Chinese observational prospective study of ageing population with chronic kidney disease (C‐OPTION)   +12 more
doaj   +1 more source

Efficacy and Safety of Daprodustat Vs rhEPO for Anemia in Patients With Chronic Kidney Disease: A Meta-Analysis and Trial Sequential Analysis

Frontiers in Pharmacology, 2022
Introduction: Daprodustat, a novel hypoxia-inducible factor prolyl-hydroxylase inhibitor (HIF-PHI), its efficacy and safety remain unclear. Thus, we conducted this meta-analysis aiming at investigating its efficacy and safety on the treatment of patients
Zhangning Fu, Zhangning Fu, Xiaodong Geng, Xiaodong Geng, Kun Chi, Kun Chi, Chengcheng Song, Chengcheng Song, Di Wu, Chao Liu, Chao Liu, Quan Hong, Quan Hong   +12 more
doaj   +1 more source

Ferroptosis and kidney disease

Nefrología (English Edition), 2020
Cell death is a finely regulated process occurring through different pathways. Regulated cell death, either through apoptosis or regulated necrosis offers the possibility of therapeutic intervention. Necroptosis and ferroptosis are among the best studied forms of regulated necrosis in the context of kidney disease.
Alberto Ortiz, Julio M. Martinez-Moreno, Miguel Fontecha-Barriuso, Ana Belen Sanz, Diego Martin-Sanchez, Melania Guerrero-Hue, Maria Dolores Sanchez-Niño, Juan Antonio Moreno, Adrian M. Ramos   +8 more
openaire   +4 more sources

Kidney disease in Paraguay [PDF]

Kidney International, 2005
Paraguay is a landlocked country located in South America with a total population of 5,884,491. Most of the population (95%) is mestizo, a mixture of Spanish and American/Indian races. The total number of indigenous people in the country has increased from 38,703 in 1981 to 85,674 in 2002.
Francisco Vicente Santa Cruz, Susana Barreto, Maria Magdalena Mayor, Walter E. Cabrera, Diana Baez   +4 more
openaire   +3 more sources