Results 51 to 60 of about 10,805,577 (430)

Long Noncoding RNAs and Their Therapeutic Promise in Diabetic Nephropathy [PDF]

, 2021
Recent advances in large-scale RNA sequencing and genome-wide profiling projects have unraveled a heterogeneous group of RNAs, collectively known as long noncoding RNAs (lncRNAs), which play central roles in many diverse biological processes. Importantly,
Coellar, Juan D, Danesh, Farhad R, Long, Jianyin   +2 more
core   +2 more sources

Progress of small ubiquitin-related modifiers in kidney diseases

Chinese Medical Journal, 2019
. Objective:. Small ubiquitin-related modifiers (SUMOs) are a group of post-translational modification proteins extensively expressed in eukaryotes. Abnormal SUMOylation can lead to the development of various diseases.
Ou Li, Qian Ma, Fei Li, Guang-Yan Cai, Xiang-Mei Chen, Quan Hong, Li-Min Chen   +6 more
doaj   +1 more source

Stem cells: a potential treatment option for kidney diseases

Stem cell research & therapeutics, 2020
The prevalence of kidney diseases is emerging as a public health problem. Stem cells (SCs), currently considered as a promising tool for therapeutic application, have aroused considerable interest and expectations.
Dongwei Liu, F. Cheng, S. Pan, Zhangsuo Liu   +3 more
semanticscholar   +1 more source

The Role of Sirtuins in Kidney Diseases

International Journal of Molecular Sciences, 2020
Sirtuins (SIRTs) are class III histone deacetylases (HDACs) that play important roles in aging and a wide range of cellular functions. Sirtuins are crucial to numerous biological processes, including proliferation, DNA repair, mitochondrial energy ...
Y. Hong, J. Kim, M. Jo, G. Ko
semanticscholar   +1 more source

An observational cohort feasibility study to identify microvesicle and miRNA biomarkers of acute kidney injury following paediatric cardiac surgery [PDF]

, 2018
The file attached to this record is the author's final peer reviewed version. The Publisher's final version can be found by following the DOI link.Objectives: Micro-RNA, small noncoding RNA fragments involved in gene regulation, and microvesicles ...
JnTala, Maria, Kumar, Tracy, Lotto, Attilio, Mariani, Silvia, Murphy, Gavin, Pais, Paolo, Smallwood, Dawn T., Sullo, Nikol, Westrope, Claire, Wozniak, Marcin   +9 more
core   +1 more source

Macrophage polarization in innate immune responses contributing to pathogenesis of chronic kidney disease

BMC Nephrology, 2020
Chronic kidney disease (CKD) is characterized by inflammation, injury and fibrosis. Dysregulated innate immune responses mediated by macrophages play critical roles in progressive renal injury. The differentiation and polarization of macrophages into pro-
Hewang Lee, Michael B. Fessler, Peng Qu, Jurgen Heymann, Jeffrey B. Kopp   +4 more
doaj   +1 more source

The Emerging Role of Innate Immunity in Chronic Kidney Diseases

International Journal of Molecular Sciences, 2020
Renal fibrosis is a common fate of chronic kidney diseases. Emerging studies suggest that unsolved inflammation will progressively transit into tissue fibrosis that finally results in an irreversible end-stage renal disease (ESRD).
P. Tang, Ying-ying Zhang, Max Kam-Kwan Chan, W. Lam, J. Chung, W. Kang, K. To, H. Lan, P. Tang   +8 more
semanticscholar   +1 more source

Better pulmonary function is associated with greater handgrip strength in a healthy Chinese Han population

BMC Pulmonary Medicine, 2020
Background Handgrip strength (HGS) has been widely studied in clinical and epidemiological settings, but the relationship between HGS and pulmonary function is still controversial.
Liangmei Chen, Xiaomin Liu, Qian Wang, Linpei Jia, Kangkang Song, Sasa Nie, Yinping Zhang, Dan Cao, Delong Zhao, Zuoxiang Li, Zheyi Dong, Ying Zheng, Shuwei Duan, Xuefeng Sun, Zhe Feng, Guangyan Cai, Weiguang Zhang, Xiangmei Chen   +17 more
doaj   +1 more source

Clinical features of acute kidney injury in patients with nephrotic syndrome and minimal change disease: a retrospective, cross-sectional study

Chinese Medical Journal, 2021
. Background:. Minimal change nephropathy (MCD) is a common pathological type of nephrotic syndrome and is often associated with acute kidney injury (AKI).
Shu-Peng Lin, Feng-Ge Zhu, Jin-Ling Meng, Xiao-Wei Sun, Jing Cui, Shuang Liang, Zhong Yin, Xue-Feng Sun, Guang-Yan Cai, Pei-Fang Wei   +9 more
doaj   +1 more source

The Complement C3a and C3a Receptor Pathway in Kidney Diseases

Frontiers in Immunology, 2020
The pathogenesis of some kidney diseases is closely associated with complement activation, where the C3a/C3a receptor (C3aR) might play a crucial role.
Shuang Gao, Z. Cui, Ming-hui Zhao
semanticscholar   +1 more source