Results 51 to 60 of about 11,405,950 (406)

Pruritus in Kidney Disease [PDF]

Seminars in Nephrology, 2015
Pruritus is a common and distressing symptom in patients with chronic kidney disease. The most recent epidemiologic data have suggested that approximately 40% of patients with end-stage renal disease experience moderate to severe pruritus and that uremic pruritus (UP) has a major clinical impact, being associated strongly with poor quality of life ...
Sara A, Combs, J Pedro, Teixeira, Michael J, Germain   +2 more
openaire   +2 more sources

Identification of novel molecular signatures of IgA nephropathy through an integrative -omics analysis [PDF]

, 2017
IgA nephropathy (IgAN) is the most prevalent among primary glomerular diseases worldwide. Although our understanding of IgAN has advanced significantly, its underlying biology and potential drug targets are still unexplored.
Cisek, Katryna, Delles, Christian, Filip, Szymon, Gakiopoulou, Chara, Jankowski, Joachim, Krochmal, Magdalena, Markoska, Katerina, Mischak, Harald, Orange, Clare, Spasovski, Goce, Vlahou, Antonia, Zoidakis, Jerome   +11 more
core   +2 more sources

Stem cells: a potential treatment option for kidney diseases

Stem cell research & therapeutics, 2020
The prevalence of kidney diseases is emerging as a public health problem. Stem cells (SCs), currently considered as a promising tool for therapeutic application, have aroused considerable interest and expectations.
Dongwei Liu, F. Cheng, S. Pan, Zhangsuo Liu   +3 more
semanticscholar   +1 more source

Clinical features of acute kidney injury in patients with nephrotic syndrome and minimal change disease: a retrospective, cross-sectional study

Chinese Medical Journal, 2021
. Background:. Minimal change nephropathy (MCD) is a common pathological type of nephrotic syndrome and is often associated with acute kidney injury (AKI).
Shu-Peng Lin, Feng-Ge Zhu, Jin-Ling Meng, Xiao-Wei Sun, Jing Cui, Shuang Liang, Zhong Yin, Xue-Feng Sun, Guang-Yan Cai, Pei-Fang Wei   +9 more
doaj   +1 more source

The Role of Sirtuins in Kidney Diseases

International Journal of Molecular Sciences, 2020
Sirtuins (SIRTs) are class III histone deacetylases (HDACs) that play important roles in aging and a wide range of cellular functions. Sirtuins are crucial to numerous biological processes, including proliferation, DNA repair, mitochondrial energy ...
Y. Hong, J. Kim, M. Jo, G. Ko
semanticscholar   +1 more source

Polycystic kidney disease [PDF]

Nature Reviews Disease Primers, 2018
Cystic kidneys are common causes of end-stage renal disease, both in children and in adults. Autosomal dominant polycystic kidney disease (ADPKD) and autosomal recessive polycystic kidney disease (ARPKD) are cilia-related disorders and the two main forms of monogenic cystic kidney diseases.
Bergmann, C., Guay-Woodford, L.M., Harris, P.C., Horie, S., Peters, D.J.M., Torres, V.E.   +5 more
openaire   +4 more sources

d-Amino acids and kidney diseases

Clinical and Experimental Nephrology, 2020
d-Amino acids are the recently detected enantiomers of l-amino acids. Accumulating evidence points their potential in solving the long-standing critical problems associated with the management of both chronic and acute kidney diseases.
Tomonori Kimura, A. Hesaka, Y. Isaka
semanticscholar   +1 more source

Better pulmonary function is associated with greater handgrip strength in a healthy Chinese Han population

BMC Pulmonary Medicine, 2020
Background Handgrip strength (HGS) has been widely studied in clinical and epidemiological settings, but the relationship between HGS and pulmonary function is still controversial.
Liangmei Chen, Xiaomin Liu, Qian Wang, Linpei Jia, Kangkang Song, Sasa Nie, Yinping Zhang, Dan Cao, Delong Zhao, Zuoxiang Li, Zheyi Dong, Ying Zheng, Shuwei Duan, Xuefeng Sun, Zhe Feng, Guangyan Cai, Weiguang Zhang, Xiangmei Chen   +17 more
doaj   +1 more source

Regulation of connective tissue growth factor expression by miR-133b for the treatment of renal interstitial fibrosis in aged mice with unilateral ureteral obstruction

Stem Cell Research & Therapy, 2021
Introduction Renal interstitial fibrosis, an important pathological feature of kidney aging and chronic renal failure, is regulated by mesenchymal stem cells (MSCs).
Dan Cao, Yuan Wang, Yingjie Zhang, Yinping Zhang, Qi Huang, Zhong Yin, Guangyan Cai, Xiangmei Chen, Xuefeng Sun   +8 more
doaj   +1 more source

Who should be prioritized for renal transplantation?: Analysis of key stakeholder preferences using discrete choice experiments [PDF]

, 2012
Background Policies for allocating deceased donor kidneys have recently shifted from allocation based on Human Leucocyte Antigen (HLA) tissue matching in the UK and USA. Newer allocation algorithms incorporate waiting time as a primary factor, and in
A Allepuz, AJ Lloyd, Ala Szczepura, Anil Gumber, C Byrne, C Byrne, CC Geddes, CJ Browning, Dennis Leech, Department of Health, DJ Street, Domenico Moro, FP Cappuccio, G Rubin, J Huber, J Neuberger, J Ratcliffe, J Ratcliffe, JM Wooldridge, K Ladkin, KC Norris, LF Ross, M Amaya-Amaya, M Bradley, MD Clark, Michael D Clark, NHS Blood and Transplant, NHS Blood and Transplant [formally UK Transplant], Nick West, ON Louis, PL Tso, R Bennett, RA Koenne, RM Higgins, Robert Higgins, S Youngkong, SN Davison, VB Ashby, VS Raleigh   +38 more
core   +4 more sources