Results 61 to 70 of about 1,448,860 (303)

Dietary patterns for adults with chronic kidney disease [PDF]

open access: yes, 2015
This is the protocol for a review and there is no abstract. The objectives are as follows: This review will evaluate the benefits and harms of dietary patterns among adults with CKD (any stage including people with end-stage kidney disease (ESKD) treated
Campbell, Katrina Louise   +8 more
core   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

In Silico Approaches and the Role of Ontologies in Aging Research [PDF]

open access: yes, 2013
The 2013 Rostock Symposium on Systems Biology and Bioinformatics in Aging Research was again dedicated to dissecting the aging process using in silico means.
Busch, Hauke   +14 more
core  

Automatic Renal Segmentation in DCE-MRI using Convolutional Neural Networks

open access: yes, 2017
Kidney function evaluation using dynamic contrast-enhanced MRI (DCE-MRI) images could help in diagnosis and treatment of kidney diseases of children. Automatic segmentation of renal parenchyma is an important step in this process.
Haghighi, Marzieh   +2 more
core   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

A new perspective on proteinuria and drug therapy for diabetic kidney disease

open access: yesFrontiers in Pharmacology
Diabetic kidney disease (DKD) is one of the leading causes of end-stage renal disease worldwide and significantly increases the risk of premature death due to cardiovascular diseases.
Ruimin Zhang   +8 more
doaj   +1 more source

Mercapturate Pathway in the Tubulocentric Perspective of Diabetic Kidney Disease [PDF]

open access: yes, 2019
BACKGROUND: The recent growing evidence that the proximal tubule underlies the early pathogenesis of diabetic kidney disease (DKD) is unveiling novel and promising perspectives.
Antunes, A   +7 more
core   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

TOTAL ULTRASOUND GUIDED PERCUTANEOUS NEPHROLITHOTOMY: A NOVEL TECHNIQUE

open access: yesGomal Journal of Medical Sciences, 2014
Introduction: Fluoroscopy is commonly used imaging technique during percutaneous nephrolithotomy but is associated with risks of radiation exposure. We evaluated the safety and efficacy of ultrasound guided Percutaneous Nephrolithotomy for treatment of ...
Anayat Ullah   +5 more
doaj  

Blood and urine biomarkers of disease progression in IgA nephropathy

open access: yesBiomarker Research
The prognosis of patients with IgA nephropathy (IgAN) is variable but overall not good. Almost all patients with IgAN are at risk of developing end-stage renal disease within their expected lifetime.
Zhi-Yu Duan   +3 more
doaj   +1 more source

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