Results 81 to 90 of about 14,135,306 (260)

Ultrasound-guided renal subcapsular transplantation of mesenchymal stem cells for treatment of acute kidney injury in a minipig model: safety and efficacy evaluation

Stem Cell Research & Therapy
Background Acute kidney injury (AKI) is a major global public health concern with limited treatment options. While preclinical studies have suggested the potential of mesenchymal stem cells (MSCs) to repair and protect injured kidneys in AKI, clinical ...
Tuo Xiao, Yuhao Chen, Bo Jiang, Mengjie Huang, Yanjun Liang, Yue Xu, Xumin Zheng, Wenjuan Wang, Xiangmei Chen, Guangyan Cai   +9 more
doaj   +1 more source

Red blood cell distribution width-to-monocyte ratio for predicting 90-day mortality of COVID-19 in patients with chronic kidney disease during the Omicron period: a prospective single-center study

Renal Failure
We aimed to test whether red blood cell distribution width (RDW) to monocyte percentage ratio (RMR) was associated with the acute-phase prognosis of coronavirus disease 2019 (COVID-19) in chronic kidney disease (CKD) patients.
Chaofan Li, Yue Niu, Dinghua Chen, Zhe Feng, Fei Liu, Yong Wang, Xueying Cao, Jie Wu, Jiabao Liu, Xuefeng Sun, Li Zhang, Guangyan Cai, Ping Li, Xiangmei Chen   +13 more
doaj   +1 more source

Association between sarcopenia and frailty in elderly patients with chronic kidney disease

Journal of Cachexia, Sarcopenia and Muscle, 2023
Background Frailty and sarcopenia are prevalent in chronic kidney disease (CKD) populations and could increase the risk for adverse health outcomes.
Che Wang, Xinru Guo, Xieguanxuan Xu, Shuang Liang, Wenling Wang, Fanglei Zhu, Siyang Wang, Jie Wu, Li Zhang, Xuefeng Sun, Xiangmei Chen, Guangyan Cai, The Chinese observational prospective study of ageing population with chronic kidney disease (C‐OPTION)   +12 more
doaj   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Evaluation of factors related to depression in peritoneal dialysis patients: a multicenter cross-sectional study

Renal Replacement Therapy, 2023
Background End-stage renal disease (ESRD) is serious global public health challenge in many developing countries. Treatment of ESRD is carried out through renal replacement therapy like peritoneal dialysis (PD).
Sepehr Bazazzadeh, Mohammad Reza Sharbafchi, Maryam Kazemi Naeini, Sayed Mohsen Hosseini, Abdolamir Atapour, Mojgan Mortazavi   +5 more
doaj   +1 more source

Therapeutic Plasma Exchange in Pediatric Kidney Disease: 23-year Experience at the Severance Children's Hospital in Korea [PDF]

, 2017
Purpose: The American Society for Apheresis provides clinical guidelines for therapeutic apheresis in adults, but there are no guidelines for children. This study aimed to analyze the effect of therapeutic plasma exchange (TPE) in pediatric patients with
이금화, 신재일, 김지홍
core   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

TOTAL ULTRASOUND GUIDED PERCUTANEOUS NEPHROLITHOTOMY: A NOVEL TECHNIQUE

Gomal Journal of Medical Sciences, 2014
Introduction: Fluoroscopy is commonly used imaging technique during percutaneous nephrolithotomy but is associated with risks of radiation exposure. We evaluated the safety and efficacy of ultrasound guided Percutaneous Nephrolithotomy for treatment of ...
Anayat Ullah, Muhammad Kamran Khan, Ata Ur Rahman, Muhammad Naeem, Sarhad Khan, Riaz Ur Rehman   +5 more
doaj  

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

A new perspective on proteinuria and drug therapy for diabetic kidney disease

Frontiers in Pharmacology
Diabetic kidney disease (DKD) is one of the leading causes of end-stage renal disease worldwide and significantly increases the risk of premature death due to cardiovascular diseases.
Ruimin Zhang, Ruimin Zhang, Qian Wang, Yaqing Li, Qihu Li, Xuefeng Zhou, Xiangmei Chen, Xiangmei Chen, Zheyi Dong   +8 more
doaj   +1 more source