Results 81 to 90 of about 857,514 (313)

Urinary angiostatin: a novel biomarker of kidney disease associated with disease severity and progression

BMC Nephrology, 2019
Background This study aimed to evaluate the value of urinary angiostatin levels for assessing disease severity and progression of IgA nephropathy (IgAN).
Yuan-Yuan Xia, Ru Bu, Guang-Yan Cai, Xue-Guang Zhang, Shu-Wei Duan, Jie Wu, Di Wu, Xiang-Mei Chen   +7 more
doaj   +1 more source

Understanding Contributors of Resilience in Youth With Childhood‐Onset Systemic Lupus Erythematosus Through a Socioecological Lens: A Mixed‐Methods Study

Arthritis Care &Research, EarlyView.
Objective This study aimed to identify themes contributing to resilience in childhood‐onset systemic lupus erythematosus (cSLE), distinguish between profiles of resilience, and examine how they relate to underlying themes and patient characteristics. Methods We conducted a mixed‐methods study of 21 patients with cSLE aged 11 to 19 years at a Canadian ...
Isabella Zaffino, Louise Boulard, Joanna Law, Asha Jeyanathan, Lawrence Ng, Sandra Williams‐Reid, Kiah Reid, Angela Cortes, Eugene Cortes, Ashley Danguecan, Deborah M. Levy, Linda T. Hiraki, Andrea M. Knight   +12 more
wiley   +1 more source

The Kidney: Structure and Function in Health and Disease. [PDF]

, 1951
Harry Goldblatt
openalex   +2 more sources

Extracellular vesicles for acute kidney injury in preclinical rodent models: a meta-analysis

Stem Cell Research & Therapy, 2020
Introduction Extracellular vesicles (EVs), especially stem cell-derived EVs, have emerged as a potential novel therapy for acute kidney injury (AKI). However, their effects remain incompletely understood.
Chao Liu, Jin Wang, Jie Hu, Bo Fu, Zhi Mao, Hengda Zhang, Guangyan Cai, Xiangmei Chen, Xuefeng Sun   +8 more
doaj   +1 more source

DISEASES OF THE KIDNEY [PDF]

Annual Review of Medicine, 1954
Elliot V. Newman, Donald G. Pocock
openaire   +3 more sources

Time trends and predictors of gout remission over six years

Arthritis Care &Research, Accepted Article.
Objectives This study aims to describe the trends in remission rates over six years of follow‐up among people with gout taking urate‐lowering therapy (ULT), and to identify variables that predict remission. Methods A post hoc analysis was conducted using data from the Cardiovascular Safety of Febuxostat or Allopurinol in Patients with Gout (CARES ...
Adwoa Dansoa Tabi‐Amponsah, Sarah Stewart, Greg Gamble, Lisa K Stamp, William J Taylor, Nicola Dalbeth   +5 more
wiley   +1 more source

Research Progress on the Role of Inflammasomes in Kidney Disease

Mediators of Inflammation, 2020
Inflammasomes are multimeric complexes composed of cytoplasmic sensors, apoptosis-associated speck-like protein containing a caspase activation and recruitment domain (ASC or PYCARD), and procaspase-1 and play roles in regulating caspase-dependent ...
Kun Chi, Xiaodong Geng, Chao Liu, GuangYan Cai, Quan Hong   +4 more
doaj   +1 more source

Activation of SIRT1 Reduces Renal Tubular Epithelial Cells Fibrosis in Hypoxia Through SIRT1‐FoxO1‐FoxO3‐Autophagy Pathway

Advanced Biology, EarlyView.
Hypoxia promotes the epithelial‐mesenchymal transition (EMT) of renal tubular epithelial cells via the SIRT1‐FoxO1‐FoxO3‐autophagy pathway, thereby resulting in the fibrosis of renal tubular epithelial cells. Activation of SIRT1 or induction of autophagy inhibits this process, alleviating hypoxia‐induced fibrosis.
Guangyu Wang, Lijuan Zhang, Jiaorong Tan, Fei Li, Yishan Jin, Limei He, Xin Yang   +6 more
wiley   +1 more source

Inhibition of ACSS2-mediated histone crotonylation alleviates kidney fibrosis via IL-1β-dependent macrophage activation and tubular cell senescence

Nature Communications
Histone lysine crotonylation (Kcr), as a posttranslational modification, is widespread as acetylation (Kac); however, its roles are largely unknown in kidney fibrosis.
Lingzhi Li, Ting Xiang, Jingjing Guo, Fan Guo, Yiting Wu, Han Feng, Jing Liu, Sibei Tao, Ping Fu, Liang Ma   +9 more
doaj   +1 more source

Cellular microRNA networks regulate host dependency of hepatitis C virus infection

Nature Communications, 2017
Using genome-wide miRNA mimic and hairpin inhibitor screens, Li et al. identify 31 miRNAs that either inhibit or promote hepatitis C virus (HCV) replication at different steps of the viral life cycle.
Qisheng Li, Brianna Lowey, Catherine Sodroski, Siddharth Krishnamurthy, Hawwa Alao, Helen Cha, Stephan Chiu, Ramy El-Diwany, Marc G. Ghany, T. Jake Liang   +9 more
doaj   +1 more source