Results 51 to 60 of about 4,209,711 (302)
Cisplatin Induced Nephrotoxicity
Cisplatin is a potent chemotherapy agent which is used to treat a broad spectrum of solid cancers. However, its clinical use is limited due to its nephrotoxicity with a decline in the glomerular filtration rate that occur in 15-30% of patients.
Seyed Seifollah Beladi Mousavi +1 more
doaj
ABSTRACT Background Japan has one of the highest dialysis prevalence rates worldwide and a shrinking, aging population. Whether dialysis burden has entered a sustained post‐peak phase or whether recent declines partly reflect pandemic‐related disruptions remains uncertain.
Hatice Şahin +2 more
wiley +1 more source
Study the activity of Tryptase And Beta 2- Microglobulin Levels In the Sera of Patients With Chronic Renal Failure And Rheumatoid Arthritis [PDF]
This work was mainly designed to study the levels of Mast Cell Tryptase & Beta 2- Microglobulin in serum of patients with chronic renal failure (CRF), which they were in the end stage of renal disease (ESDR) depending on hemodialysis (HD) and chronic ...
Sabah H. Khorsheed +2 more
doaj +1 more source
The prevalence and identification of chronic kidney disease in Switzerland [PDF]
BACKGROUND: Chronic kidney disease (CKD) is characterized by a gradual loss of kidney function. Patients in early CKD stages are often asymptomatic or show non-specific symptoms.
Tomonaga, Yuki
core +1 more source
ABSTRACT Introduction Peritoneal dialysis (PD) is an established home‐based kidney replacement therapy (KRT), but its uptake remains low in Japan. We evaluated whether individualized education in a dedicated outpatient clinic was associated with the initiation of PD.
Yasuko Ito +7 more
wiley +1 more source
BackgroundObesity or overweight is well known to be a strong risk factor for the development of hypertension. However, the association of body mass index (BMI) within the normal range and its trajectory with new-onset hypertension in adults remains ...
Hongxue Yu +42 more
doaj +1 more source
Cardiorenal relationships in patients with chronic heart failure with preserved ejection fraction
The combination of heart and kidney diseases caused by chronic heart failure and aggravated by kidney damage, called cardiorenal syndrome, is increasingly recognized as a critical pathological unit, leading to a worsening of the prognosis in patients ...
Yu. N. Panina, V. I. Vishnevsky
doaj +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Commentary on the burden of chronic kidney disease
The kidneys are two bean shaped organs situated in the abdomen that is responsible for the excretion of metabolic waste, production of hormones, and metabolism and excretion of drugs and toxins amongst others. Chronic renal failure is said to occur when
Unadike B
doaj +1 more source
Essential hypertension (EH) is one of the most common cardiovascular diseases worldwide, entailing a high level of morbidity. EH is a multifactorial disease influenced by both genetic and environmental factors, including mitochondrial DNA (mtDNA ...
Yuqi Liu +4 more
doaj +1 more source

