Results 61 to 70 of about 685,068 (311)

RETRACTED: Mitochondrial tRNA Mutations Associated With Essential Hypertension: From Molecular Genetics to Function

Frontiers in Cell and Developmental Biology, 2021
Essential hypertension (EH) is one of the most common cardiovascular diseases worldwide, entailing a high level of morbidity. EH is a multifactorial disease influenced by both genetic and environmental factors, including mitochondrial DNA (mtDNA ...
Yuqi Liu, Yuqi Liu, Yuqi Liu, Yuqi Liu, Yundai Chen   +4 more
doaj   +1 more source

World kidney day 2014: Kidney disease and elderly [PDF]

, 2014
It is believed that there is an increasing rate of chronic kidney disease to end-stage kidney failure. Nowadays, there is an international awareness on the importance of chronic kidney disease as well as declining the frequency and impact of renal ...
Amiri, Masoud., Hajivandi, Abdollah.
core  

Berberine–cinnamic acid co‐crystal effect in ameliorating hyperlipidemia might be regulated through the PI3K/AKT/mTOR/SREBP‐1 signaling pathway

FEBS Open Bio, EarlyView.
Berberine–cinnamic acid co‐crystal (BBR‐CA) inhibits the phosphorylation of the phosphatidylinositol 3‐kinase (PI3K)/AKT/mammalian target of rapamycin (mTOR) pathway, suppressing the transfer of pre‐sterol regulatory element‐binding proteins‐1 (SREBP‐1) from the endoplasmic reticulum to the nucleus. This results in a decrease in the expression level of
Wenheng Gao, Yunlong Li, Lihua Chen, Wenshuo Yang, Yong He, Ye Yang, Dengke Yin, Song Tan   +7 more
wiley   +1 more source

Posttraumatic growth in chronic kidney failure disease

Procedia - Social and Behavioral Sciences, 2010
SummaryIt was aimed to determine the posttraumatic growth level of the patients with hemodialysis and to examine the supposed effect of socio-demographic variables, variables associated with disease, perceived social support and ways of coping. Research data were collected by 491 patients in private dialysis centers.
Seda Bayraktar, Hatice Yorulmaz, Kursat Ozdilli   +2 more
openaire   +2 more sources

Activation of Rac-1 and RhoA contributes to podocyte injury in chronic kidney disease [PDF]

, 2013
Rho-family GTPases like RhoA and Rac-1 are potent regulators of cellular signaling that control gene expression, migration and inflammation. Activation of Rho-GTPases has been linked to podocyte dysfunction, a feature of chronic kidney diseases (CKD). We
Amann, Kerstin, Babelova, Andrea, Brandes, Ralf Peter Louis, Daniel, Christoph, Fork, Christian, Jansen, Felix, Jung, Oliver, Löhn, Matthias, Pavenstädt, Hermann, Plettenburg, Oliver, Ruetten, Hartmut, Sander, Kerstin, Schäfer, Liliana, Stark, Holger   +13 more
core   +4 more sources

Diabetes‐induced vascular calcification is associated with low pyrophosphate and its oral supplementation prevents calcification in diabetic mice

FEBS Open Bio, EarlyView.
Induction of diabetes in three different mouse strains uniformly resulted in an increase in TNAP activity and a reduction in pyrophosphate (PPi) in the circulation. Inhibition of TNAP restored plasma PPi. Diabetes‐induced calcification in the media layer of the aorta was detected only in the Abcc6−/− strain, which is predisposed to ectopic ...
Krisztina Fülöp, Eszter Kozák, Natália Tőkési, Lilian Kocsis, Anikó Kelemen, Zsuzsanna Geszti, Adriána Kutás, Mariann Harangi, Ágnes Diószegi, Zsolt Rapi, József Balla, Olivier Le Saux, András Váradi, Viola Pomozi   +13 more
wiley   +1 more source

Cisplatin Induced Nephrotoxicity

مجله دانشگاه علوم پزشکی بیرجند, 2014
Cisplatin is a potent chemotherapy agent which is used to treat a broad spectrum of solid cancers. However, its clinical use is limited due to its nephrotoxicity with a decline in the glomerular filtration rate that occur in 15-30% of patients.
Seyed Seifollah Beladi Mousavi, Abbas Ali Zeraati   +1 more
doaj  

Cardiorenal Nexus: A Review With Focus on Combined Chronic Heart and Kidney Failure, and Insights From Recent Clinical Trials

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2022
The cardiorenal nexus encompasses a bidirectional relationship between the heart and the kidneys. Chronic abnormalities in cardiac function can lead to progressive kidney disease, and chronic kidney disease can lead to progressively decreasing cardiac ...
Peter A. McCullough, Alpesh Amin, Kevin M. Pantalone, Claudio Ronco   +3 more
doaj   +1 more source

Moyamoya Disease and the Risk of Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives Moyamoya disease (MMD) is a rare cerebrovascular disorder characterized by the progressive narrowing of arteries at the base of the brain, forming abnormal collateral vascular networks. While vascular parkinsonism is noted in MMD, its link to Parkinson's disease (PD) has not been explored.
Dallah Yoo, Jeong‐Yong Shin, Rugyeom Lee, Jiwon Cheon, Ji Hun Kim, Doeun Kim, Jae‐Kyung Won, In‐Hwan Oh, Yunjong Lee, Tae‐Beom Ahn   +9 more
wiley   +1 more source

Effects of tolvaptan in patients with chronic kidney disease and chronic heart failure [PDF]

Clinical and Experimental Nephrology, 2017
Tolvaptan, a vasopressin V2 receptor blocker, has a diuretic effect for patients with heart failure. However, there were a few data concerning the effects of tolvaptan in patients with chronic kidney disease (CKD).We retrospectively analyzed 21 patients with chronic heart failure and CKD. Tolvaptan was co-administered with other diuretics in-use, every
Mari Katsumata, Nobuhito Hirawa, Koichiro Sumida, Minako Kagimoto, Yosuke Ehara, Yuki Okuyama, Megumi Fujita, Akira Fujiwara, Mayumi Kobayashi, Yusuke Kobayashi, Yuichiro Yamamoto, Sanae Saka, Keisuke Yatsu, Tetsuya Fujikawa, Yoshiyuki Toya, Gen Yasuda, Kouichi Tamura, Satoshi Umemura   +17 more
openaire   +3 more sources