Study the activity of Tryptase And Beta 2- Microglobulin Levels In the Sera of Patients With Chronic Renal Failure And Rheumatoid Arthritis [PDF]
This work was mainly designed to study the levels of Mast Cell Tryptase & Beta 2- Microglobulin in serum of patients with chronic renal failure (CRF), which they were in the end stage of renal disease (ESDR) depending on hemodialysis (HD) and chronic ...
Sabah H. Khorsheed+2 more
doaj +1 more source
From omics to AI—mapping the pathogenic pathways in type 2 diabetes
Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan+2 more
wiley +1 more source
Renal effects and associated outcomes during angiotensin-neprilysin inhibition in heart failure [PDF]
Objectives: The purpose of this study was to evaluate the renal effects of sacubitril/valsartan in patients with heart failure and reduced ejection fraction.
Claggett, Brian+14 more
core +4 more sources
Chronic kidney disease, heart failure and neprilysin inhibition [PDF]
AbstractPatients with chronic kidney disease are at increased risk of cardiovascular disease and this often manifests clinically like heart failure. Conversely, patients with heart failure frequently have reduced kidney function. The links between the kidneys and cardiovascular system are being elucidated, with blood pressure being a key risk factor ...
Philip A. Kalra+9 more
openaire +3 more sources
Current trends in single‐cell RNA sequencing applications in diabetes mellitus
Single‐cell RNA sequencing is a powerful approach to decipher the cellular and molecular landscape at a single‐cell resolution. The rapid development of this technology has led to a wide range of applications, including the detection of cellular and molecular mechanisms and the identification and introduction of novel potential diagnostic and ...
Seyed Sajjad Zadian+6 more
wiley +1 more source
Gambaran Penerimaan Diri Pasien Gagal Ginjal Kronis yang Menjalani Hemodialisis [PDF]
Background : Patients with chronic kidney failure undergo hemodialysis twice a week as a renal replacement therapy. Self-acceptance is crucial to support the implementation of hemodialysis therapy. Objective: To explore the overview of self-acceptance in
Rohmatuloh, Junialdo Yusuf
core
Metabolic Consequences of Rheumatoid Arthritis
Patients with rheumatoid arthritis (RA) may have metabolic disruption, which can contribute to adverse long‐term outcomes, for multiple reasons. Patients with RA appear to have a higher risk of sarcopenia, type 1 and type 2 diabetes mellitus, metabolic syndrome, and hypertension. Systemic inflammation in RA can cause a “lipid paradox,” with reduced low‐
Stevie Barry+2 more
wiley +1 more source
Acute kidney injury on chronic kidney disease: From congestive heart failure to light chain deposition disease and cast nephropathy in multiple myeloma [PDF]
Acute on chronic renal failure is a common but notably broad diagnosis. We present a 64-year-old man with a history of diastolic heart failure and chronic kidney disease, admitted for an elevated creatinine.
Cheng, Steven+3 more
core +1 more source
Commentary on the burden of chronic kidney disease
The kidneys are two bean shaped organs situated in the abdomen that is responsible for the excretion of metabolic waste, production of hormones, and metabolism and excretion of drugs and toxins amongst others. Chronic renal failure is said to occur when
Unadike B
doaj +1 more source
Objective This study aimed to identify themes contributing to resilience in childhood‐onset systemic lupus erythematosus (cSLE), distinguish between profiles of resilience, and examine how they relate to underlying themes and patient characteristics. Methods We conducted a mixed‐methods study of 21 patients with cSLE aged 11 to 19 years at a Canadian ...
Isabella Zaffino+12 more
wiley +1 more source