Results 81 to 90 of about 1,257,254 (358)

Asuhan Keperawatan Pada Tn. N Dengan Gangguan Sistem Perkemihan: Gagal Ginjal Kronik Di Ruang Anggrek Bugenvil RSUD Pandan Arang Boyolali [PDF]

, 2015
Background: Globally chronic kidney disease caused the death of about 850,000 inhabitants annually, while Indonesia in 2006 reached 100,000 people with chronic kidney disease, and in Boyolali district, especially in RSUD.Pandanarang has reached 8 ...
, Agus Sudaryanto, S.Kep., Ns., M.Kes, MUSTIKA RATRI, ANGGI   +1 more
core  

The rationale, design and baseline data of FLOW, a kidney outcomes trial with once-weekly semaglutide in people with type 2 diabetes and chronic kidney disease

Nephrology, Dialysis and Transplantation, 2023
Background Chronic kidney disease (CKD) is a common complication of type 2 diabetes (T2D). Glucagon-like peptide-1 receptor agonists (GLP-1RAs) improve glycaemic control and lower body weight in people with T2D, and some reduce the risk of cardiovascular
P. Rossing, F. Baeres, G. Bakris, H. Bosch‐Traberg, M. Gislum, S. Gough, T. Idorn, J. Lawson, K. Mahaffey, JohannesF. E. Mann, H. Mersebach, V. Perkovic, K. Tuttle, R. Pratley   +13 more
semanticscholar   +1 more source

Proteasomal degradation of intracellularly expressed Amblyomin‐X limits suicide gene therapy potential in melanoma cells

FEBS Open Bio, EarlyView.
This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel, Carlos DeOcesano Pereira, Aline Ramos Maia Lobba, Melissa Regina Fessel, Ana Marisa Chudzinski‐Tavassi   +4 more
wiley   +1 more source

Prognostic robustness of serum creatinine based AKI definitions in patients with sepsis: a prospective cohort study [PDF]

, 2015
Background: It is unclear how modifications in the way to calculate serum creatinine (sCr) increase and in the cut-off value applied, influences the prognostic value of Acute Kidney Injury (AKI).
Dhondt, Annemieke, Lameire, Norbert, Van Biesen, Wim, Vanholder, Raymond, Vanmassenhove, Jill   +4 more
core   +2 more sources

Finerenone in heart failure and chronic kidney disease with type 2 diabetes: FINE-HEART pooled analysis of cardiovascular, kidney and mortality outcomes

Nature Medicine
Cardiovascular-kidney-metabolic syndrome is an emerging entity that connects cardiovascular diseases, chronic kidney disease and diabetes. The non-steroidal mineralocorticoid receptor antagonist finerenone has been studied in three prospective randomized
M. Vaduganathan, G. Filippatos, B. Claggett, A. Desai, P. Jhund, A. Henderson, Meike D. Brinker, P. Kolkhof, Patrick Schloemer, James Lay‐Flurrie, Prabhakar Viswanathan, C. Lam, M. Senni, Sanjiv J. Shah, A. Voors, F. Zannad, P. Rossing, L. Ruilope, S. Anker, B. Pitt, R. Agarwal, John J. V. McMurray, Scott D. Solomon   +22 more
semanticscholar   +1 more source

Natural Products as Geroprotective Modulators in Diabetic Nephropathy: A Mechanistic Framework Integrating Aging Hallmarks and the AMPK–SIRT1–Nrf2 Axis

Aging and Cancer, EarlyView.
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu, Latif Adams, Eunice Ampem‐Danso, Justice Kumi, Abigail Aning, Fatima Hamidu, Mustapha Abdul Mumin Mohammed, Ayuba Nii Darku Ankrah, Seth Kwabena Amponsah   +8 more
wiley   +1 more source

Prognostic Implications of Sleep Architecture for Patients Admitted to the Intensive Care Unit With Status Epilepticus

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Status epilepticus (SE) is associated with significant mortality. Sleep architecture may reflect normal brain function. Impaired sleep architecture is associated with poorer outcomes in numerous conditions. Here we investigate the association of sleep architecture in continuous EEG (cEEG) with survival in SE.
Ran R. Liu, Marcus C. Ng, Gavin P. Winston, Sabrina Schaly, Garima Shukla, Lysa Boissé Lomax   +5 more
wiley   +1 more source

Renal function in chronic heart failure : a cohort study [PDF]

, 2014
University of Technology Sydney. Faculty of Health.Renal dysfunction is strongly associated with adverse health outcomes in chronic heart failure. The term cardio-renal syndrome has been proposed to describe the theoretical models developed to explain ...
Sheerin, NJ
core  

Diffusion Spectrum Imaging Maps Early Axonal Loss and a Unique Progressive Signal in Neuronal Intranuclear Inclusion Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To delineate specific in vivo white matter pathology in neuronal intranuclear inclusion disease (NIID) using diffusion spectrum imaging (DSI) and define its clinical relevance. Methods DSI was performed on 42 NIID patients and 38 matched controls.
Kaiyan Jiang, Yixiu Pei, Xiaobao Hu, Ying Xiong, Fang Wang, Yanyan Yu, Min Zhu, Dandan Tan, Meihong Zhou, Daojun Hong, Fuqing Zhou   +10 more
wiley   +1 more source

Using Serum Interleukin-18 (IL-18) as a Biomarker of Chronic Kidney Failure and its relationship with Prolactin Level

Tikrit Journal of Pure Science, 2020
Kidney failure usually occurs as a result of lacking the normal functions of kidney as either partly or completely. In the last years, it was announced that the Interleukin-18 has received significant interest as inflame marker.
Wasan Abdul Malik Izz al-Din, , Nadia Ibrahim Salih   +1 more
doaj   +1 more source