Results 21 to 30 of about 1,022,396 (355)

dCubilin- or dAMN-mediated protein reabsorption in Drosophila nephrocytes modulates longevity

Disease Models & Mechanisms, 2021
Aging is a multifaceted process regulated by multiple cellular pathways, including the proteostasis network. Pharmacological or genetic enhancement of the intracellular proteostasis network extends lifespan and prevents age-related diseases. However, how
Xiaoming Feng, Xizhen Hong, Qiuxia Fan, Liting Chen, Jing Li, Juan Deng, Siqiao Gong, Fan Fan Hou, Fujian Zhang   +8 more
doaj   +1 more source

Kidney Failure and Dialysis

Nephrology & Renal Therapy, 2021
In earlier communications [1,2], minor lapses in the healthcare centers are pointed out. In this article, health issues per se pertaining to patients undergoing dialysis are discussed.
Fostoria Court, Uppaluri Ramakrishna Rao
openaire   +1 more source

Dual mTOR/PI3K inhibition limits PI3K-dependent pathways activated upon mTOR inhibition in autosomal dominant polycystic kidney disease [PDF]

, 2018
Autosomal dominant polycystic kidney disease (ADPKD) is characterized by the development of kidney cysts leading to kidney failure in adulthood. Inhibition of mammalian target of rapamycin (mTOR) slows polycystic kidney disease (PKD) progression in ...
Arcaro, Alexandre, Castelletti, Deborah, Fu, Xuebin, Liu, Yang, Mischak, Harald, Mullen, William, Pejchinovski, Martin, Serra, Andreas L., Siwy, Justyna, Wang, Xueqi, Watnick, Terry J.   +10 more
core   +2 more sources

Association of accelerometer-measured physical activity intensity, sedentary time, and exercise time with incident Parkinson’s disease

npj Digital Medicine, 2023
Evidence regarding the association between physical activity and Parkinson’s disease (PD) risk is generally limited due to the use of self-report questionnaires.
Mengyi Liu, Xiaoqin Gan, Ziliang Ye, Yuanyuan Zhang, Panpan He, Chun Zhou, Sisi Yang, Yanjun Zhang, Xianhui Qin   +8 more
doaj   +1 more source

A new outlook towards kidney injuries [PDF]

, 2012
Acute and chronic progression of injury to the kidney leads to the failure of the renal system and has become an increasingly important cause of morbidity and mortality.
Abhijeet Satwekar, Mahesh Satwekar
core   +2 more sources

PIRCHE-II is related to graft failure after kidney transplantation [PDF]

, 2018
Individual HLA mismatches may differentially impact graft survival after kidney transplantation. Therefore, there is a need for a reliable tool to define permissible HLA mismatches in kidney transplantation.
Allebes, W.A. (Wil), Baas, M.C. (Marije), Bemelman, F.J. (Fréderike), Berge, I.J.M. (Ineke) ten, Betjes, M.G.H. (Michiel), Bots, M.L. (Michiel L.), Bungener, L.B., Christiaans, M.H. (Maarten), Claas, F.H.J. (Frans), Drylewicz, J. (Julia), Fijter, J.W. (Johan) de, Gelens, M., Geneugelijk, K. (Kirsten), Hack, C.E. (Erik), Heidt, P.J. (Peter), Hepkema, B.G. (Bouke), Hilbrands, L.B. (Luuk), Hoitsma, A.J. (Andries), Joosten, I. (Irma), Kamburova, E.G., Lambeck, A.J.A. (Annechien J.A.), Lardy, J.N.M. (Junior N.M.), Niemann, M. (Matthias), Nurmohamed, A., Otten, H.G. (Henderikus), Roelen, D.L. (Dave), Roozendaal, C., Sanders, J.S.F., Seelen, M.A.J., Spierings, E. (E.), Swelsen, W.T., Tilanus, M.G.J. (Marcel), van der Boog, P.J.M., van der Meer, A., van der Pant, K.A., van Duijnhoven, E., van Ittersum, F., van Reekum, F., van Zuilen, A.D. (Arjan D.), Vanderlocht, J. (Joris), Verhaar, M.C. (Marianne), Voorter, C.E.M. (C. E M), Weerd, N.C. (Neelke) van der, Wieten, L.   +43 more
core   +8 more sources

Epidemiology of acute kidney injury in hospitalized pregnant women in China

BMC Nephrology, 2019
Background Epidemiologic data of acute kidney injury (AKI) during pregnancy is lacking in China. This study aims to determine the effect of pregnancy on the risk of AKI among hospitalized women of childbearing age, and to describe the incidence, risk ...
Diankun Liu, Wenjuan He, Yanqin Li, Mengqi Xiong, Long Wang, Jingxin Huang, Ling Jia, Shuling Yuan, Sheng Nie   +8 more
doaj   +1 more source

Habitual glucosamine use, APOE genotypes, and risk of incident cause-specific dementia in the older population

Alzheimer’s Research & Therapy, 2023
Background The relationship of glucosamine use with incident dementia in the older population remains uncertain. We aimed to evaluate the longitudinal association between habitual glucosamine supplement and the risk of cause-specific dementia and examine
Chun Zhou, Yanjun Zhang, Sisi Yang, Ziliang Ye, Qimeng Wu, Mengyi Liu, Panpan He, Yuanyuan Zhang, Xianhui Qin   +8 more
doaj   +1 more source

Leukemia inhibitory factor is a therapeutic target for renal interstitial fibrosisResearch in context

EBioMedicine, 2022
Summary: Background: The role of the IL6 family members in organ fibrosis, including renal interstitial fibrosis (TIF), has been widely explored. However, few studies have ever simultaneously examined them in the same cohort of patients.
Shihui Xu, Xiaobing Yang, Qingzhou Chen, Zhuoliang Liu, Ying Chen, Xiaotian Yao, An Xiao, Jianwei Tian, Liling Xie, Miaomiao Zhou, Zheng Hu, Fengxin Zhu, Xin Xu, Fanfan Hou, Jing Nie   +14 more
doaj   +1 more source

Estimating the total incidence of kidney failure in australia including individuals who are not treated by dialysis or transplantation [PDF]

, 2013
Background: To date, incidence data for kidney failure in Australia have been available for only those who start renal replacement therapy (RRT). Information about the total incidence of kidney failure, including non-RRT-treated cases, is important to ...
Cass, Alan, Chadban, Steve, Chapman, Jeremy, Green, Frances, Hoy, Wendy, Mathew, Tim, McDonald, Stephen, Moon, Lynelle, Sparke, Claire   +8 more
core   +1 more source