Results 21 to 30 of about 4,640,867 (405)
Kidney failure in Bardet–Biedl syndrome
Clinical Genetics, 2022 The aim of this study was to explore kidney failure (KF) in Bardet–Biedl syndrome (BBS), focusing on high‐risk gene variants, demographics, and morbidity. We employed the Clinical Registry Investigating BBS (CRIBBS) to identify 44 (7.2%) individuals with
Jennifer R. Meyer +6 more
semanticscholar +1 more source
Detecting and Treating Lung Congestion with Kidney Failure.
American Society of Nephrology. Clinical Journal, 2022 Fluid overload is a common complication in patients with CKD, particularly patients with kidney failure, a population with a very high risk for pulmonary edema.
Carmine Zoccali, F. Mallamaci, E. Picano
semanticscholar +1 more source
Physiological Reports, 2021 Chronic kidney disease (CKD) has a high prevalence worldwide and is an intricate issue to whole medical society. Renal fibrosis is the common pathological feature for various kinds of CKD.
Jinhua Miao +7 more
doaj +1 more source
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2016 BackgroundAlthough several risk factors for acute kidney injury (AKI) have been identified, early detection of AKI in acute decompensated heart failure patients remains a challenge. The aim of this study was to develop and validate a risk score for early
Li Zhi Zhou +6 more
doaj +1 more source
A Klotho-derived peptide protects against kidney fibrosis by targeting TGF-β signaling
Nature Communications, 2022 Klotho is an anti-ageing protein whose expression is downregulated in chronic kidney disease, but the large size of the protein makes it challenging to deliver therapeutically.
Qian Yuan +11 more
doaj +1 more source
Kidney Transplant Failure [PDF]
Clinical Journal of the American Society of Nephrology, 2014 Kidney transplant failure is an important cause of dialysis initiation in the United States. In 2011, this group represented 4.7% of patients new to dialysis, a 30% increase in the number of patients initiating dialysis after transplant failure since 2000 ([1][1]).
openaire +2 more sources
International Journal of Environmental Research and Public Health, 2022 Background: Kidney failure is a global health problem with a worldwide mean prevalence rate of 13.4%. Kidney failure remains symptomless during most of the early stages until symptoms appear in the advanced stages.
M. Butt +8 more
semanticscholar +1 more source
dCubilin- or dAMN-mediated protein reabsorption in Drosophila nephrocytes modulates longevity
Disease Models & Mechanisms, 2021 Aging is a multifaceted process regulated by multiple cellular pathways, including the proteostasis network. Pharmacological or genetic enhancement of the intracellular proteostasis network extends lifespan and prevents age-related diseases. However, how
Xiaoming Feng +8 more
doaj +1 more source
Dual mTOR/PI3K inhibition limits PI3K-dependent pathways activated upon mTOR inhibition in autosomal dominant polycystic kidney disease [PDF]
, 2018 Autosomal dominant polycystic kidney disease (ADPKD) is characterized by the development of kidney cysts leading to kidney failure in adulthood. Inhibition of mammalian target of rapamycin (mTOR) slows polycystic kidney disease (PKD) progression in ...
Arcaro, Alexandre +10 more
core +2 more sources
BMC Nephrology, 2021 Background Patients with kidney failure treated with dialysis or kidney transplantation experience difficulties maintaining employment due to the condition itself and the treatment. We aimed to establish the rate of employment before and after initiation
L. Kirkeskov +3 more
semanticscholar +1 more source