Results 81 to 90 of about 911,122 (332)
Background: Fasting before surgery is a necessity, but prolonged fasting can lead to serious complications such as decreased perfusion and organ dysfunction.
Kokab Basirimoghadam+5 more
doaj +1 more source
Prediction of Kidney Function from Biopsy Images Using Convolutional Neural Networks [PDF]
A Convolutional Neural Network was used to predict kidney function in patients with chronic kidney disease from high-resolution digital pathology scans of their kidney biopsies. Kidney biopsies were taken from participants of the NEPTUNE study, a longitudinal cohort study whose goal is to set up infrastructure for observing the evolution of 3 forms of ...
arxiv
Thoracic ectopic kidney in adults. A report of 2 cases [PDF]
Thoracic kidney is the rarest, usually asymptomatic type of kidney ectopia. 2 cases of thoracic kidney discovered incidentally through chest radiography are reported.
Czekajska-Chehab, Elżbieta+4 more
core +1 more source
Nuclear prothymosin α inhibits epithelial‐mesenchymal transition (EMT) in lung cancer by increasing Smad7 acetylation and competing with Smad2 for binding to SNAI1, TWIST1, and ZEB1 promoters. In early‐stage cancer, ProT suppresses TGF‐β‐induced EMT, while its loss in the nucleus in late‐stage cancer leads to enhanced EMT and poor prognosis.
Liyun Chen+12 more
wiley +1 more source
A case of sponge kidney associated with pyelon e phritis arisen in 39 years old man was reported. Discussions were made on its patho-histological findings and clinical pictures. 1.
巾, 拓磨+3 more
core
Assessment of cognitive dysfunction in kidney disease [PDF]
Background: Cognitive dysfunction, include reducedmental alertness, intellectual impairment, decreasedattention and concentration, memory deficits anddiminished perceptual-motor coordination.
El Shahawy, Yasser+3 more
core +2 more sources
Landscape of BRAF transcript variants in human cancer
We investigate the annotation of BRAF variants, focusing on protein‐coding BRAF‐220 (formerly BRAF‐reference) and BRAF‐204 (BRAF‐X1). The IsoWorm pipeline allows us to quantify these variants in human cancer, starting from RNA‐sequencing data. BRAF‐204 is more abundant than BRAF‐220 and impacts patient survival.
Maurizio S. Podda+5 more
wiley +1 more source
TRPM8 levels determine tumor vulnerability to channel agonists
TRPM8 is a Ca2+ permissive channel. Regardless of the amount of its transcript, high levels of TRPM8 protein mark different tumors, including prostate, breast, colorectal, and lung carcinomas. Targeting TRPM8 with channel agonists stimulates inward calcium currents followed by emptying of cytosolic Ca2+ stores in cancer cells.
Alessandro Alaimo+18 more
wiley +1 more source
The diagnostic importance of the new marker KIM-1 in kidney damage [PDF]
In recent years, the rapid development of scientific research led to the introduction of strategies based on new markers that allow for estimation of the latent disease period before the clinical symptoms of actual kidney failure are revealed.The ...
Joanna Płonka, Zofia Marchewka
core +1 more source
Loss of primary cilia in endothelial cells promotes EndMT and vascular abnormalities in the ovarian tumor microenvironment through EphA2 activation. Using human samples, in vitro models, and endothelial‐specific Kif3a‐knockout mice, we show that primary cilia loss drives the acquisition of cancer‐associated fibroblast‐like phenotypes, thereby ...
Jin Gu Cho+11 more
wiley +1 more source