Results 81 to 90 of about 911,122 (332)

The Relationship between Fasting Duration before Urological Surgeries and Postoperative Renal Function

open access: yesمجله دانشکده پزشکی اصفهان, 2020
Background: Fasting before surgery is a necessity, but prolonged fasting can lead to serious complications such as decreased perfusion and organ dysfunction.
Kokab Basirimoghadam   +5 more
doaj   +1 more source

Prediction of Kidney Function from Biopsy Images Using Convolutional Neural Networks [PDF]

open access: yesarXiv, 2017
A Convolutional Neural Network was used to predict kidney function in patients with chronic kidney disease from high-resolution digital pathology scans of their kidney biopsies. Kidney biopsies were taken from participants of the NEPTUNE study, a longitudinal cohort study whose goal is to set up infrastructure for observing the evolution of 3 forms of ...
arxiv  

Thoracic ectopic kidney in adults. A report of 2 cases [PDF]

open access: yes, 2003
Thoracic kidney is the rarest, usually asymptomatic type of kidney ectopia. 2 cases of thoracic kidney discovered incidentally through chest radiography are reported.
Czekajska-Chehab, Elżbieta   +4 more
core   +1 more source

Aberrant expression of nuclear prothymosin α contributes to epithelial‐mesenchymal transition in lung cancer

open access: yesMolecular Oncology, EarlyView.
Nuclear prothymosin α inhibits epithelial‐mesenchymal transition (EMT) in lung cancer by increasing Smad7 acetylation and competing with Smad2 for binding to SNAI1, TWIST1, and ZEB1 promoters. In early‐stage cancer, ProT suppresses TGF‐β‐induced EMT, while its loss in the nucleus in late‐stage cancer leads to enhanced EMT and poor prognosis.
Liyun Chen   +12 more
wiley   +1 more source

Sponge kidney [PDF]

open access: yes, 1965
A case of sponge kidney associated with pyelon e phritis arisen in 39 years old man was reported. Discussions were made on its patho-histological findings and clinical pictures. 1.
巾, 拓磨   +3 more
core  

Assessment of cognitive dysfunction in kidney disease [PDF]

open access: yes, 2010
Background: Cognitive dysfunction, include reducedmental alertness, intellectual impairment, decreasedattention and concentration, memory deficits anddiminished perceptual-motor coordination.
El Shahawy, Yasser   +3 more
core   +2 more sources

Landscape of BRAF transcript variants in human cancer

open access: yesMolecular Oncology, EarlyView.
We investigate the annotation of BRAF variants, focusing on protein‐coding BRAF‐220 (formerly BRAF‐reference) and BRAF‐204 (BRAF‐X1). The IsoWorm pipeline allows us to quantify these variants in human cancer, starting from RNA‐sequencing data. BRAF‐204 is more abundant than BRAF‐220 and impacts patient survival.
Maurizio S. Podda   +5 more
wiley   +1 more source

TRPM8 levels determine tumor vulnerability to channel agonists

open access: yesMolecular Oncology, EarlyView.
TRPM8 is a Ca2+ permissive channel. Regardless of the amount of its transcript, high levels of TRPM8 protein mark different tumors, including prostate, breast, colorectal, and lung carcinomas. Targeting TRPM8 with channel agonists stimulates inward calcium currents followed by emptying of cytosolic Ca2+ stores in cancer cells.
Alessandro Alaimo   +18 more
wiley   +1 more source

The diagnostic importance of the new marker KIM-1 in kidney damage [PDF]

open access: yes, 2013
In recent years, the rapid development of scientific research led to the introduction of strategies based on new markers that allow for estimation of the latent disease period before the clinical symptoms of actual kidney failure are revealed.The ...
Joanna Płonka, Zofia Marchewka
core   +1 more source

Loss of primary cilia promotes EphA2‐mediated endothelial‐to‐mesenchymal transition in the ovarian tumor microenvironment

open access: yesMolecular Oncology, EarlyView.
Loss of primary cilia in endothelial cells promotes EndMT and vascular abnormalities in the ovarian tumor microenvironment through EphA2 activation. Using human samples, in vitro models, and endothelial‐specific Kif3a‐knockout mice, we show that primary cilia loss drives the acquisition of cancer‐associated fibroblast‐like phenotypes, thereby ...
Jin Gu Cho   +11 more
wiley   +1 more source

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