Systematic analysis of a novel human renal glomerulus-enriched gene expression dataset. [PDF]
, 2010 Glomerular diseases account for the majority of cases with chronic renal failure. Several genes have been identified with key relevance for glomerular function.
Anders, Hans-Joachim +8 more
core +12 more sources
Segment-specific expression of 2P domain potassium channel genes in human nephron. [PDF]
, 2004 BackgroundThe 2P domain potassium (K2P) channels are a recently discovered ion channel superfamily. Structurally, K2P channels are distinguished by the presence of two pore forming loops within one channel subunit. Functionally, they are characterized by
Bockenhauer, Detlef +3 more
core +1 more source
High-resolution imaging of kidney vascular corrosion casts with nano-CT [PDF]
, 2010 A vascular corrosion cast of an entire mouse kidney was scanned with a modular multiresolution X-ray nanotomography system. Using an isotropic voxel pitch of 0.5 mu m, capillary systems such as the vasa recta, peritubular capillaries and glomeruli were ...
Czymmek, Kirk +5 more
core +1 more source
New Descriptor for Glomerulus Detection in Kidney Microscopy Image [PDF]
, 2015 Glomerulus detection is a key step in histopathological evaluation of microscopy images of kidneys. However, the task of automatic detection of glomeruli poses challenges due to the disparity in sizes and shapes of glomeruli in renal sections.
Hayliang Ngouv +6 more
core +2 more sources
Pleiotropy as the Mechanism for Evolving Novelty: Same Signal, Different Result. [PDF]
, 2015 In contrast to the probabilistic way of thinking about pleiotropy as the random expression of a single gene that generates two or more distinct phenotypic traits, it is actually a deterministic consequence of the evolution of complex physiology from the ...
Torday, John S
core +5 more sources
Effects of Raw Ethanolic Seed Extract of Tetracarpidium conophorum on Heamatological and Histopathological Parameters in Swiss Albino Mice Infected with Plasmodium berghei [PDF]
, 2017 Study was carried out to determine the heamatological and histopathological effects of raw ethanolic seed extract of Tetracarpidium conophorum in swiss albino mice infected with Plasmodium berghei (NK65).
D. A. Oloruntola +3 more
core +1 more source
Upregulation of Transglutaminase andε(γ-Glutamyl)-Lysine in the Fisher-Lewis Rat Model of Chronic Allograft Nephropathy [PDF]
, 2014 Background. Tissue transglutaminase (TG2), a cross-linking enzyme, modulates deposition of extracellular matrix protein in renal fibrosis. This study aimed to examine TG2 and its cross-link product ε(γ-glutamyl)-lysine in the Fisher-Lewis rat renal ...
Butt, Imran +7 more
core +3 more sources
Localization of the succinate receptor in the distal nephron and its signaling in polarized MDCK cells [PDF]
, 2009 When the succinate receptor (SUCNR1) is activated in the afferent arterioles of the glomerulus it increases renin release and induces hypertension.
Deen +37 more
core +1 more source
Targeting kidney mesangium by nanoparticles of defined size [PDF]
, 2011 Nanoparticles are being investigated for numerous medical applications and are showing potential as an emerging class of carriers for drug delivery. Investigations on how the physicochemical properties (e.g., size, surface charge, shape, and density of ...
C. H. J. Choi +19 more
core +2 more sources
Inhalation of mercury vapor can cause the toxic effects on rat kidney [PDF]
, 2016 Dental amalgam has been used in dentistry as a filling material. The filler comprises mercury (Hg). It is considered one of the most important and widespread environmental pollutants, which poses a serious potential threat for the humans and animals ...
Akgul, Hayati Murat +5 more
core +1 more source