Results 161 to 170 of about 1,061,703 (360)
Animal Models and Experimental Medicine, EarlyView.The current study characterized temporal changes in glomerular gene expression, pathology, and biomarkers in a mouse model of hypertension‐accelerated diabetic kidney disease (DKD). Progressive albuminuria and glomerulosclerosis were paralleled by dynamic transcriptomic changes associated withmetabolic dysfunction, extracellular matrix remodeling, and ...
Adam B. Marstrand‐Jørgensen +8 more
wiley +1 more source
Comprehending the Membrane Properties for Emulation in Organs‐on‐a‐Chip
Advanced NanoBiomed Research, EarlyView.The advent of organ‐on‐chip models allows closer emulation of in vivo conditions, leading to effective, less costly, and specific drugs. Although a number of membrane‐based on‐chip models exist, better emulating functional models need to be devised for organ simulations.
Tanmayee Makarand Sathe +1 more
wiley +1 more source
The Anatomical Record, EarlyView.Abstract As habitat salinity markedly differs between the endangered, freshwater‐dwelling Saimaa ringed seal (Pusa saimensis Nordquist, 1899) and the brackish water‐inhabiting Baltic ringed seal (Pusa hispida botnica Gmelin, 1788), we investigated whether this difference has resulted in morphological changes to their kidneys.
Heini Nihtilä, Juha Laakkonen
wiley +1 more source
Ultrasmall polymeric nanocarriers for drug delivery to podocytes in kidney glomerulus
Journal of Controlled Release, 2017 R. Bruni +7 more
semanticscholar +1 more source
Animal Research and One Health, EarlyView.Mechanisms of light in regulating the chick pineal clock. Abstract The circadian clock significantly impacts animal health and productivity, with light playing a crucial role in regulating circadian rhythms. However, the mechanisms behind light‐induced circadian transmission remain unclear, particularly in light‐sensitive avian species.
Yunlei Li +10 more
wiley +1 more source
Animal Research and One Health, EarlyView.Dietary selenium (Se) deficiency is recognized as a global problem, and exogenous Se supplementation can effectively enrich its levels in animal bodies. Offal tissues are equally important as meat in Se enrichment. Varying properties among Se species require information beyond total Se concentration to fully evaluate health risk/benefits.
Xiaoqing Guo +9 more
wiley +1 more source
Renal tubulointerstitial damage and salt-sensitive hypertension in chronic kidney disease: is the tubulointerstitium relevant beyond the glomerulus? [PDF]
, 2014 Kentaro Kohagura, Yusuke Ohya
openalex +1 more source
Mucosal‐Associated Invariant T Cells in Rheumatic Diseases
Arthritis &Rheumatology, EarlyView.Mucosal‐associated invariant T (MAIT) cells are innate‐like T cells defined by their semi‐invariant T cell receptor and restriction by the major histocompatibility complex class I–related molecule (MR1). These cells are primarily activated by microbial‐derived metabolites presented by MR1 or by cytokines.
Manon Lesturgie‐Talarek +7 more
wiley +1 more source
Arthritis &Rheumatology, EarlyView.Objective Dotinurad is a selective urate reabsorption inhibitor that reduces serum urate levels. We compared the efficacy and safety of dotinurad with febuxostat in Chinese patients with gout. Methods This phase 3, multicenter, randomized, double‐blind, parallel‐group study randomly allocated (1:1) eligible patients with gout to receive oral dotinurad ...
Jia Sun +19 more
wiley +1 more source