Kidney Lipidomics by Mass Spectrometry Imaging: A Focus on the Glomerulus [PDF]
International Journal of Molecular Sciences, 2019 Lipid disorders have been associated with glomerulopathies, a distinct type of renal pathologies, such as nephrotic syndrome. Global analyses targeting kidney lipids in this pathophysiologic context have been extensively performed, but most often ...
Imane Abbas +5 more
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Endothelin and the glomerulus in chronic kidney disease. [PDF]
Seminars in Nephrology, 2015 Endothelin-1 (ET-1) is a 21-amino acid peptide with mitogenic and powerful vasoconstricting properties. Under healthy conditions, ET-1 is expressed constitutively in all cells of the glomerulus and participates in homeostasis of glomerular structure and filtration function.
M. Barton, A. Sorokin
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Myocilin is expressed in the glomerulus of the kidney and induced in mesangioproliferative glomerulonephritis [PDF]
Kidney International, 2004 Myocilin is a 55 to 57 kD secreted glycoprotein and member of the olfactomedin protein family. It is expressed in high amounts in the outflow tissues of the aqueous humor in the eye where it is supposed to contribute to outflow resistance. Myocilin is mutated in some forms of primary open angle glaucoma and affected patients show very high intraocular ...
Andreas Goldwich +5 more
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Detection of renin lineage cell transdifferentiation to podocytes in the kidney glomerulus with dual lineage tracing. [PDF]
Kidney Int, 2018 Eng DG +7 more
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Revealing VCAN as a Potential Common Diagnostic Biomarker of Renal Tubules and Glomerulus in Diabetic Kidney Disease Based on Machine Learning, Single-Cell Transcriptome Analysis and Mendelian Randomization [PDF]
Diabetes & Metabolism JournalBackground Diabetic kidney disease (DKD) is recognized as a significant complication of diabetes mellitus and categorized into glomerular DKDs and tubular DKDs, each governed by distinct pathological mechanisms and biomarkers.
Li Jiang, Jie Jian, Xulin Sai, Xiai Wu
doaj +3 more sources
Beyond the Glomerulus—Kidney Tubule Markers and Diabetic Kidney Disease Progression [PDF]
Kidney International Reports, 2021 Alexander L. Bullen, Pranav S. Garimella
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Investigations of cytoplasmic contractile and cytoskeletal elements in the kidney glomerulus.
Kidney International, 1981 Electron microscopy and in vitro techniques were used to evaluate the morphologic responses of glomerular podocytes and glomerular endothelial cells to compounds that affect either cytoplasmic contractile elements or cytoplasmic microtubules. In response to in vitro incubation in the presence of cytochalasin D or B (compounds that inhibit contraction ...
P. Andrews
semanticscholar +3 more sources
Proteome studies, with emphasis on the kidney glomerulus
, 2012 Proteomics aims to link genes to protein expression and function. Proteomics is a very versatile and technology-dependent discipline and the development of mass spectrometry-based proteomics has advanced the understanding of the complex and dynamic nature of proteomes.
Sam Tryggvason
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11β-Hydroxysteroid Dehydrogenase Type 2 Is Expressed in the Human Kidney Glomerulus [PDF]
, 2002 Saeko Kataoka +11 more
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Analysis of the three dimensional structure of the kidney glomerulus capillary network. [PDF]
Sci Rep, 2020 Terasaki M, Brunson JC, Sardi J.
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