Results 151 to 160 of about 2,281,812 (411)

Systematic Review: Kidney Transplantation Compared With Dialysis in Clinically Relevant Outcomes

American Journal of Transplantation, 2011
Individual studies indicate that kidney transplantation is associated with lower mortality and improved quality of life compared with chronic dialysis treatment.
M. Tonelli, N. Wiebe, G. Knoll, A. Bello, S. Browne, D. Jadhav, S. Klarenbach, J. Gill   +7 more
semanticscholar   +1 more source

Horseshoe kidney transplantation

The Surgeon, 2003
Even though the number of patients awaiting renal transplant is rapidly increasing, the donor pool remains relatively stable. In an attempt to increase this pool, marginal kidneys and kidneys with congenital anatomical variations are being used. Horseshoe kidneys, being the most common renal fusion anomaly, can provide a useful solution to the ever ...
Zipitis, C S, Augustine, T, Tavakoli, A, Surange, R, Agrawal, A, Riad, H N   +5 more
openaire   +4 more sources

Rictor Ameliorates Acute Antibody‐Mediated Rejection Following Kidney Transplantation by Suppressing Macrophage M1 Polarization Through p65‐NLRP3 Axis

Advanced Science, EarlyView.
This study elucidates the critical role of Rictor in macrophage activation in acute antibody‐mediated rejection (ABMR). Rictor increases K48‐linked ubiquitination of p65 by upregulating E3 ubiquitin ligase SOCS1, inhibiting transcriptional levels of NLRP3 and inflammasome activation.
Bin Ni, Chengcheng Yang, Junqi Zhang, Zhou Hang, Ming Zheng, Dengyuan Feng, Qinghuan Shen, Jinxu Miao, Xulin Sun, Li Sun, Baixin Shen, Min Gu, Zijie Wang   +12 more
wiley   +1 more source

A comparative study of clinical outcomes and risk factors of tuberculosis in kidney transplant recipients from deceased donors

European Journal of Medical Research
Objective To investigate the clinical characteristics, diagnosis and treatment of tuberculosis infection after deceased donor kidney transplantation and to analyze the risk factors and prognosis of tuberculosis infection through a paired case–control ...
Hedong Zhang, Mingda Zhong, Shanbiao Hu, Liang Tan, Longkai Peng, Xubiao Xie, Gongbin Lan   +6 more
doaj   +1 more source

Long-Term Efficacy of Treatment with Cyclosporine in Idiopathic Membranous Nephropathy: Remission Is Not Enough

Turkish Journal of Nephrology
Background: Membranous nephropathy (MN) is an autoimmune disease in which circulating autoantibodies bind to a podocyte antigen, causing nephrotic syndrome. Despite several treatment options, their long-term benefits are still not established. The aim of
Marios Papasotiriou, Adamantia Mpratsiakou, Paraskevi Pavlakou, Evangelos Papachristou, Pantelitsa Kalliakmani, Dimitrios S Goumenos   +5 more
doaj   +1 more source

An unusual cause of renal failure; Epstein syndrome [PDF]

Journal of Nephropharmacology, 2016
Epstein syndrome constitutes macrothrombocytopenia without neutrophil inclusion bodies along with deafness and renal failure. A diagnosis of Epstein syndrome was made in a 17 year-old-male patient with macrothrombopathic thrombocytopenia, renal failure ...
Balwani Manish R, Engineer Divyesh P, Gumber Manoj R, Kute Vivek B, Singh Rajesh, Patel Himanshu V, Vanikar Aruna V, Gera Dinesh, Shah Pankaj R, Trivedi Hargovind L   +9 more
doaj  

Exosomes From Intestinal Epithelial Cells Promote Hepatic Differentiation of Liver Progenitor Cells in Gut‐Liver‐on‐a‐Chip Models

Advanced Science, EarlyView.
The effects of intestinal epithelial cells and their exosomes on the hepatic differentiation of HPCs are explored in a gut‐liver‐on‐a‐chip. Exosomes from intestinal epithelial cells improve liver fibrosis. Moreover, the miR‐371‐373 cluster in the exosomes may mediate this effect by regulating the hepatic differentiation of HPCs.
Liang Ye, Shi Li, Guofang Bi, Binghui Li, Zhai Cai, Meixian Jin, Ying Zhang, Wanren Yang, Yang Li, Shao Li, Wei Hu, Yi Gao, Mingxin Pan, Shuqin Zhou, Chao Zhang, Huichang Bi, Qing Peng   +16 more
wiley   +1 more source

Red Blood Cell‐Induced Bacterial Margination Improves Microbial Hemoadsorption on Engineered Cell‐Depleted Thrombi, Restoring Severe Bacteremia in Rats

Advanced Science, EarlyView.
A highly efficient extracorporeal device for treating bacteremia is developed by integrating microfluidic bacterial margination and engineered cell‐depleted thrombi strategically constructed in the device. The rodent models, severely infected with antibiotic‐resistant bacteria, recover from bacteremia after two subsequent extracorporeal blood ...
Bong Hwan Jang, Su Hyun Jung, Seyong Kwon, Sung Jin Park, Joo H. Kang   +4 more
wiley   +1 more source

Irisin Attenuates Pulmonary Vascular Remodeling in Pulmonary Arterial Hypertension via Ubiquitin‐Mediated Regulation of ENO1

Advanced Science, EarlyView.
Irisin is a crucial plasma biomarker and promising therapeutic target that reflects disease severity, pulmonary vascular remodeling status and clinical outcome in patients with pulmonary arterial hypertension (PAH). As a novel protective factor, irisin is downregulated in PAH. By ubiquitination, irisin promotes Enolase 1 degradation and suppresses cell
Na Sun, Yong‐Bing Wang, Jing Huang, Run‐Wei Deng, Hui‐Yu He, Lei Gao, Xuan Gao, You‐Li Fan, Yan Cong, Yao‐Lei Guo, Yi‐Qiang Chen, Gui‐Jia Wang, Shao‐Hong Fang, Xia Gu, Bo Yu, Bing‐Xiang Wu   +15 more
wiley   +1 more source

Exploring the relationship between graft dysfunction with serum metabolites and inflammatory proteins: integrating Mendelian randomization, single-cell analysis, machine learning, and SHAP methods for comprehensive analysis

Renal Failure
Background The exact mechanism of graft dysfunction has not been fully clarified. We aimed to explore the causal effects of serum metabolites on graft dysfunction and the mediating role of inflammatory proteins.Methods We first analyzed the causal ...
Jiyuan Li, Kankan Shui, Longkai Peng, Helong Dai, Fenghua Peng   +4 more
doaj   +1 more source